Engineering long-circulating nanomaterial delivery systems

Size-Transformable Hyaluronan Stacked Self-Assembling Peptide Nanoparticles for Improved Transcellular Tumor Penetration and Photo–Chemo Combination Therapy

(2020) Zhaoqing Cong et al.   ACS Nano

Nanoscavenger provides long-term prophylactic protection against nerve agents in rodents

(2019) Peng Zhang et al.   Science Translational Medicine

Elimination Pathways of Nanoparticles

(2019) Wilson Poon et al.   ACS Nano

The Interplay between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses

(2019) Seyed Moein Moghimi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Erythrocyte leveraged chemotherapy (ELeCt): Nanoparticle assembly on erythrocyte surface to combat lung metastasis

(2019) Zongmin Zhao et al.   Science Advances

Biodegradable zwitterionic polymer membrane coating endowing nanoparticles with ultra-long circulation and enhanced tumor photothermal therapy

(2019) Shaojun Peng et al.   BIOMATERIALS

The Blood Clearance Kinetics and Pathway of Polymeric Micelles in Cancer Drug Delivery

(2018) Xuanrong Sun et al.   ACS Nano

Erythrocyte–Cancer Hybrid Membrane Camouflaged Hollow Copper Sulfide Nanoparticles for Prolonged Circulation Life and Homotypic-Targeting Photothermal/Chemotherapy of Melanoma

(2018) Dongdong Wang et al.   ACS Nano

Bioengineered Boronic Ester Modified Dextran Polymer Nanoparticles as Reactive Oxygen Species Responsive Nanocarrier for Ischemic Stroke Treatment

(2018) Wei Lv et al.   ACS Nano

Complement Activation by PEGylated Gold Nanoparticles

(2018) Quang Huy Quach et al.   BIOCONJUGATE CHEMISTRY

Zwitterionic stealth peptide-protected gold nanoparticles enable long circulation without the accelerated blood clearance phenomenon

(2018) Jue Zhao et al.   Biomaterials Science

Micelles with ultralow critical micelle concentration as carriers for drug delivery

(2018) Yang Lu et al.   Nature Biomedical Engineering

Dense and Dynamic Polyethylene Glycol Shells Cloak Nanoparticles from Uptake by Liver Endothelial Cells for Long Blood Circulation

(2018) Hao Zhou et al.   ACS Nano

Revealing the Immunogenic Risk of Polymers

(2018) Bowen Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing

(2018) Hongliang He et al.   NANO LETTERS

Block copolymer crystalsomes with an ultrathin shell to extend blood circulation time

(2018) Hao Qi et al.   Nature Communications

Transport and interactions of nanoparticles in the kidneys

(2018) Bujie Du et al.   Nature Reviews Materials

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

(2018) Vivian P. Vu et al.   Nature Nanotechnology

Emerging Role of the Spleen in the Pharmacokinetics of Monoclonal Antibodies, Nanoparticles and Exosomes

(2017) Mauro Cataldi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glomerular barrier behaves as an atomically precise bandpass filter in a sub-nanometre regime

(2017) Bujie Du et al.   Nature Nanotechnology

Stem-Cell-Membrane Camouflaging on Near-Infrared Photoactivated Upconversion Nanoarchitectures for in Vivo Remote-Controlled Photodynamic Therapy

(2016) Changyong Gao et al.   ACS Applied Materials & Interfaces

Short- and Long-Term Tracking of Anionic Ultrasmall Nanoparticles in Kidney

(2016) Xiaowen Liang et al.   ACS Nano

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Hyaluronidase Embedded in Nanocarrier PEG Shell for Enhanced Tumor Penetration and Highly Efficient Antitumor Efficacy

(2016) Hao Zhou et al.   NANO LETTERS

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

(2016) Lena M. Kranz et al.   NATURE

Mechanism of hard-nanomaterial clearance by the liver

(2016) Kim M. Tsoi et al.   NATURE MATERIALS

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

A Facile Approach to Functionalize Cell Membrane-Coated Nanoparticles

(2016) Hao Zhou et al.   Theranostics

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

Anticancer Platelet-Mimicking Nanovehicles

(2015) Quanyin Hu et al.   ADVANCED MATERIALS

A paradigm shift in platelet transfusion therapy

(2015) J. Cho   BLOOD

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Poly(carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production

(2014) Wei Yang et al.   Nano Today

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

A biomimetic nanosponge that absorbs pore-forming toxins

(2013) Che-Ming J. Hu et al.   Nature Nanotechnology

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Superhydrophilic Zwitterionic Polymers Stabilize Liposomes

(2012) Zhiqiang Cao et al.   LANGMUIR

Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

(2012) Alessandro Parodi et al.   Nature Nanotechnology

The Open Microcirculation in Human Spleens

(2011) Birte Steiniger et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Protection of Nonself Surfaces from Complement Attack by Factor H-Binding Peptides: Implications for Therapeutic Medicine

(2011) You-Qiang Wu et al.   JOURNAL OF IMMUNOLOGY

Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

(2011) C.-M. J. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE