Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

(2020) Li Wang et al.   NATURE CELL BIOLOGY

Using human genetics to understand the disease impacts of testosterone in men and women

(2020) Katherine S Ruth et al.   NATURE MEDICINE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Independence of HIF1a and androgen signaling pathways in prostate cancer

(2020) Maxine G. B. Tran et al.   BMC CANCER

COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options

(2020) Tomasz J Guzik et al.   CARDIOVASCULAR RESEARCH

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

(2020) Pierre Bost et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin

(2020) Anwarul Hasan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Clinical Characteristics of Covid-19 in New York City

(2020) Parag Goyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer

(2020) Dingxiao Zhang et al.   Nature Communications

Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Tao Guo et al.   JAMA Cardiology

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?

(2020) Bingwen Liu et al.   JOURNAL OF AUTOIMMUNITY

Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic in Paris, France: prospective observational study

(2020) Julie Toubiana et al.   BMJ-British Medical Journal

Clinical and Immune Features of Hospitalized Pediatric Patients With Coronavirus Disease 2019 (COVID-19) in Wuhan, China

(2020) Huan Wu et al.   JAMA Network Open

Generation of lung organoids from human pluripotent stem cells in vitro

(2019) Alyssa J. Miller et al.   Nature Protocols

A human embryonic stem cell reporter line for monitoring chemical-induced cardiotoxicity

(2019) Su-Yi Tsai et al.   CARDIOVASCULAR RESEARCH

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

(2019) Christopher S. Smillie et al.   CELL

Efficient RNP-Directed Human Gene Targeting Reveals SPDEF is Required for IL-13-Induced Mucostasis

(2019) Kyung Duk Koh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A Metastable Atrial State Underlies The Primary Genetic Substrate for MYL4 Mutation-Associated Atrial Fibrillation

(2019) Zaniar Ghazizadeh et al.   CIRCULATION

Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighbors

(2018) Laleh Haghverdi et al.   NATURE BIOTECHNOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

Prospective Isolation of ISL1 + Cardiac Progenitors from Human ESCs for Myocardial Infarction Therapy

(2018) Zaniar Ghazizadeh et al.   Stem Cell Reports

Glycogen synthase kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture

(2018) Ana Luisa Rodrigues Toste de Carvalho et al.   DEVELOPMENT

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

ZINC 15 – Ligand Discovery for Everyone

(2015) Teague Sterling et al.   Journal of Chemical Information and Modeling

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

TMPRSS2 and ADAM17 Cleave ACE2 Differentially and Only Proteolysis by TMPRSS2 Augments Entry Driven by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein

(2013) A. Heurich et al.   JOURNAL OF VIROLOGY

The Androgen Receptor in Health and Disease

(2012) Takahiro Matsumoto et al.   Annual Review of Physiology

Optimally weighted Z-test is a powerful method for combining probabilities in meta-analysis

(2011) D. V. ZAYKIN   JOURNAL OF EVOLUTIONARY BIOLOGY

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

(2010) Michael A. Whitt   JOURNAL OF VIROLOGICAL METHODS

Revealing Global Regulatory Perturbations across Human Cancers

(2009) Hani Goodarzi et al.   MOLECULAR CELL