A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor

Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism

(2020) Jia Wang et al.   CELL RESEARCH

Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors

(2020) Shanshan Ma et al.   MOLECULAR CELL

Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation

(2020) Yi-Lynn Liang et al.   MOLECULAR CELL

Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein

(2020) Kazuhiro Kobayashi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of Gs and Gi recognition by the human glucagon receptor

(2020) Anna Qiao et al.   SCIENCE

Structural insights into the activation of GLP-1R by a small molecule agonist

(2020) Honglei Ma et al.   CELL RESEARCH

Structural basis for activation of the growth hormone-releasing hormone receptor

(2020) Fulai Zhou et al.   Nature Communications

Pharmacological evidence for the relationship between the NMDA receptor and nitric oxide pathway and the antidepressant-like effects of glucagon-like peptide-2 in the mouse forced-swim test

(2019) Sachie Sasaki-Hamada et al.   BEHAVIOURAL BRAIN RESEARCH

Structural Insights into the Process of GPCR-G Protein Complex Formation

(2019) Xiangyu Liu et al.   CELL

Illuminating G-Protein-Coupling Selectivity of GPCRs

(2019) Asuka Inoue et al.   CELL

Effects of centrally administered glucagon-like peptide-2 on blood pressure and barosensitive neurons in spontaneously hypertensive rats

(2018) Sachie Sasaki-Hamada et al.   NEUROPEPTIDES

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Structure of the glucagon receptor in complex with a glucagon analogue

(2018) Haonan Zhang et al.   NATURE

Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor

(2018) Yi-Lynn Liang et al.   NATURE

Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex

(2018) Yi-Lynn Liang et al.   NATURE

High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist

(2018) Janosch Ehrenmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

(2017) Yi-Lynn Liang et al.   NATURE

Crystal structure of the GLP-1 receptor bound to a peptide agonist

(2017) Ali Jazayeri et al.   NATURE

Structure of the full-length glucagon class B G-protein-coupled receptor

(2017) Haonan Zhang et al.   NATURE

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

(2017) Gaojie Song et al.   NATURE

Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein

(2017) Yan Zhang et al.   NATURE

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

Antidepressant-like effects exerted by the intranasal administration of a glucagon-like peptide-2 derivative containing cell-penetrating peptides and a penetration-accelerating sequence in mice

(2017) Sachie Sasaki-Hamada et al.   PEPTIDES

Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs

(2017) J. Bernard Heymann   PROTEIN SCIENCE

The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer

(2016) Ping Liu et al.   ACTA PHARMACOLOGICA SINICA

Current and potential therapeutic targets of glucagon-like peptide-2

(2016) Kaori Austin et al.   CURRENT OPINION IN PHARMACOLOGY

Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors

(2016) Li-Hua Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLP2: an underestimated signal for improving glycaemic control and insulin sensitivity

(2016) Antonella Amato et al.   JOURNAL OF ENDOCRINOLOGY

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Influence of glucagon-like peptide 2 on energy homeostasis

(2016) Sara Baldassano et al.   PEPTIDES

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

(2015) Andrew S. Dixon et al.   ACS Chemical Biology

Immunohistochemical determination of the site of antidepressant-like effects of glucagon-like peptide-2 in ACTH-treated mice

(2015) S. Sasaki-Hamada et al.   NEUROSCIENCE

Physiology and Pharmacology of the Enteroendocrine Hormone Glucagon-Like Peptide-2

(2013) Daniel J. Drucker et al.   Annual Review of Physiology

Neuronal Fos-like immunoreactivity associated with dexamethasone-induced hypertension in rats and effects of glucagon-like peptide-2

(2013) Sachie Sasaki-Hamada et al.   LIFE SCIENCES

Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

(2013) D. Wootten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Immunohistochemical determination of the site of hypotensive effects of glucagon-like peptide-2 in the rat brain

(2012) S. Sasaki-Hamada et al.   NEUROSCIENCE

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PositiveVersusNegative Modulation of Different Endogenous Chemokines for CC-chemokine Receptor 1 by Small Molecule Agonists through AllostericVersusOrthosteric Binding

(2008) Pia C. Jensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY