Translation and Replication Dynamics of Single RNA Viruses

Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP

(2020) Byungil Kim et al.   MOLECULAR CELL

Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay

(2019) Tim A. Hoek et al.   MOLECULAR CELL

Strand-specific affinity of host factor hnRNP C1/C2 guides positive to negative-strand ratio in Coxsackievirus B3 infection

(2019) Pratik Dave et al.   RNA Biology

Biochemistry and Molecular Biology of Flaviviruses

(2018) Nicholas J. Barrows et al.   CHEMICAL REVIEWS

The life cycle of non-polio enteroviruses and how to target it

(2018) Jim Baggen et al.   NATURE REVIEWS MICROBIOLOGY

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages

(2018) Sinu P. John et al.   Cell Reports

The Strategy of Picornavirus Evading Host Antiviral Responses: Non-structural Proteins Suppress the Production of IFNs

(2018) Yining Wang et al.   Frontiers in Microbiology

Single-cell analysis of early antiviral gene expression reveals a determinant of stochastic IFNB1 expression

(2017) Sultan Doğanay et al.   Integrative Biology

In situimaging of mitochondrial translation shows weak correlation with nucleoid DNA intensity and no suppression during mitosis

(2017) Christopher Estell et al.   JOURNAL OF CELL SCIENCE

Systematic characterization of maturation time of fluorescent proteins in living cells

(2017) Enrique Balleza et al.   NATURE METHODS

HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus

(2017) Dahlene N. Fusco et al.   Frontiers in Microbiology

Real-Time Imaging of Translation on Single mRNA Transcripts in Live Cells

(2016) Chong Wang et al.   CELL

Dynamics of Translation of Single mRNA Molecules In Vivo

(2016) Xiaowei Yan et al.   CELL

Visualization of single endogenous polysomes reveals the dynamics of translation in live human cells

(2016) Xavier Pichon et al.   JOURNAL OF CELL BIOLOGY

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

(2016) Yize Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translation dynamics of single mRNAs in live cells and neurons

(2016) B. Wu et al.   SCIENCE

Real-time quantification of single RNA translation dynamics in living cells

(2016) T. Morisaki et al.   SCIENCE

Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication

(2016) Youichi Suzuki et al.   PLoS Pathogens

A Single-Cell Transcriptome Atlas of the Human Pancreas

(2016) Mauro J. Muraro et al.   Cell Systems

Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection

(2015) Sonali Patil et al.   Science Signaling

The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family

(2015) Lonneke van der Linden et al.   PLoS Pathogens

Regulation of mRNA translation during mitosis

(2015) Marvin E Tanenbaum et al.   eLife

Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus

(2015) Dylan Flather et al.   Frontiers in Microbiology

Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection

(2015) Sonali Patil et al.   Science Signaling

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

(2014) Marvin E. Tanenbaum et al.   CELL

Norovirus gene expression and replication

(2013) L. G. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Single-molecule mRNA detection and counting in mammalian tissue

(2013) Anna Lyubimova et al.   Nature Protocols

Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5'-terminal regions of cap0-, cap1- and 5'ppp- mRNAs

(2013) P. Kumar et al.   NUCLEIC ACIDS RESEARCH

Viral subversion of host functions for picornavirus translation and RNA replication

(2012) Amanda J Chase et al.   Future Virology

Tinkering with Translation: Protein Synthesis in Virus-Infected Cells

(2012) D. Walsh et al.   Cold Spring Harbor Perspectives in Biology

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA

(2011) Andreas Pichlmair et al.   NATURE IMMUNOLOGY

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

Dis3-like 1: a novel exoribonuclease associated with the human exosome

(2010) Raymond H J Staals et al.   EMBO JOURNAL

New Insights into the Role of RNase L in Innate Immunity

(2010) Arindam Chakrabarti et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members

(2010) Stephane Daffis et al.   NATURE

Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

(2009) H. S. Oh et al.   JOURNAL OF VIROLOGY

GBF1, a Guanine Nucleotide Exchange Factor for Arf, Is Crucial for Coxsackievirus B3 RNA Replication

(2009) K. H. W. Lanke et al.   JOURNAL OF VIROLOGY

Altered interactions between stem-loop IV within the 5′ noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: Effects on IRES-mediated translation and viral infectivity

(2009) Polen Sean et al.   VIROLOGY

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS