Glycoconjugates for glucose transporter-mediated cancer-specific targeting and treatment

Oligosaccharide-camptothecin conjugates as potential antineoplastic drugs: Design, synthesis and biological evaluation

(2020) Maolin Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Glucose-conjugated platinum(IV) complexes as tumor-targeting agents: design, synthesis and biological evaluation

(2019) Haifeng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbohydrate‐based nanomaterials for biomedical applications

(2019) Soeun Gim et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Monosaccharide Analogues of Anticancer Peptide R-Lycosin-I: Role of Monosaccharide Conjugation in Complexation and the Potential of Lung Cancer Targeting and Therapy

(2019) Peng Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

(2018) Pierre-Benoit Ancey et al.   FEBS Journal

Applications of Cancer Cell-Specific Aptamers in Targeted Delivery of Anticancer Therapeutic Agents

(2018) Minhee Kim et al.   MOLECULES

Protected and De-protected Platinum(IV) Glycoconjugates With GLUT1 and OCT2-Mediated Selective Cancer Targeting: Demonstrated Enhanced Transporter-Mediated Cytotoxic Properties in vitro and in vivo

(2018) Jing Ma et al.   Frontiers in Chemistry

Mechanistic and biological characteristics of different sugar conjugated 2-methyl malonatoplatinum(II) complexes as new tumor targeting agents

(2017) Xiangqian Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding Properties for Drug Delivery

(2017) Jing Ma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Uptake of glucose-conjugated MGMT inhibitors in cancer cells: role of flippases and type IV P-type ATPases

(2017) Karl-Heinz Tomaszowski et al.   Scientific Reports

Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation

(2016) Qing-Li He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells

(2016) Malay Patra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting Iron in Colon Cancer via Glycoconjugation of Thiosemicarbazone Prochelators

(2016) Eman A. Akam et al.   BIOCONJUGATE CHEMISTRY

Design, Synthesis of Novel Platinum(II) Glycoconjugates, and Evaluation of Their Antitumor Effects

(2016) Jianbin Han et al.   Chemical Biology & Drug Design

d- Versusl-Glucose Conjugation: Mitochondrial Targeting of a Light-Activated Dual-Mode-of-Action Ruthenium-Based Anticancer Prodrug

(2016) Lucien N. Lameijer et al.   CHEMISTRY-A EUROPEAN JOURNAL

Methyl 6-Amino-6-deoxy-d-pyranoside-Conjugated Platinum(II) Complexes for Glucose Transporter (GLUT)-Mediated Tumor Targeting: Synthesis, Cytotoxicity, and Cellular Uptake Mechanism

(2016) Taoli Li et al.   ChemMedChem

Synthesis and Biological Evaluation of Iodoglucoazomycin (I-GAZ), an Azomycin-Glucose Adduct with Putative Applications in Diagnostic Imaging and Radiotherapy of Hypoxic Tumors

(2016) Piyush Kumar et al.   ChemMedChem

Galactose conjugated platinum(II) complex targeting the Warburg effect for treatment of non-small cell lung cancer and colon cancer

(2016) Meng Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical Approach to Positional Isomers of Glucose–Platinum Conjugates Reveals Specific Cancer Targeting through Glucose-Transporter-Mediated Uptake in Vitro and in Vivo

(2016) Malay Patra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

(2016) Carly C. Barron et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters

(2016) Dong Deng et al.   PROTEIN SCIENCE

Glucose conjugated platinum(II) complex: Antitumor superiority to oxaliplatin, combination effect and mechanism of action

(2015) Hong Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

2-Deoxyglucose conjugated platinum (II) complexes for targeted therapy: design, synthesis, and antitumor activity

(2015) Qian Mi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeted Cancer Therapy with a 2-Deoxyglucose-Based Adriamycin Complex

(2013) J. Cao et al.   CANCER RESEARCH

Highly water-soluble platinum(ii) complexes as GLUT substrates for targeted therapy: improved anticancer efficacy and transporter-mediated cytotoxic properties

(2013) Pengxing Liu et al.   CHEMICAL COMMUNICATIONS

Glucose conjugation for the specific targeting and treatment of cancer

(2013) Emilia C. Calvaresi et al.   Chemical Science

Glufosfamide: can we improve the process of anticancer agent development?

(2012) Denis Lacombe   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Design, Synthesis, and Preliminary Biological Evaluation of 6-O-Glucose–Azomycin Adducts for Diagnosis and Therapy of Hypoxic Tumors

(2012) Piyush Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbohydrate Dependent Targeting of Cancer Cells by Bleomycin−Microbubble Conjugates

(2009) Jean-Charles Chapuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Targeting the Delivery of Glycan-Based Paclitaxel Prodrugs to Cancer Cells via Glucose Transporters

(2008) Yih-Shyan Lin et al.   JOURNAL OF MEDICINAL CHEMISTRY