Article
Materials Science, Paper & Wood
Yijun Yao, Yanqin Shen, Chengmeng Hu, Hailiang Wu
Summary: A comfortable microenvironment can be achieved by using superabsorbent fabrics in personal protective equipment. A superabsorbent and high-water-retention fabric was prepared by in situ polymerization of Starch-Sodium Alginate-Polyacrylate (St-SA-PAA) hydrogel on polyester fabric. The water-absorption rate of the fabric increased from 2.8 to 10 g/min with the deposition of St-SA-PAA gel on the fabric, and the water absorption capacity reached 343 g/g. The mechanical properties of the gel improved after water absorption due to the supporting effect of the polyester fiber. The superabsorbent fabric exhibited isotropic characteristics and its water absorption capacity and softness could be adjusted by controlling the amount of deposited gel.
Article
Polymer Science
Arlina Prima Putri, Ranjita K. Bose, Mochamad Chalid, Francesco Picchioni
Summary: Alginate dialdehyde and l-lysine-functionalized alginate dialdehyde were synthesized and characterized. The NMR analysis confirmed the introduction of l-lysine functionality, and FTIR spectroscopy revealed the formation of Schiff base covalent linkage after crosslinking. The hydrogels with l-lysine-functionalized alginate dialdehyde exhibited higher modulus storage rate and showed shear-thinning and self-healing properties. The concentration and stoichiometric ratio of alginate dialdehyde, l-lysine-functionalized alginate dialdehyde, and gelatin played a fundamental role in the mechanical properties of the hydrogel.
Article
Engineering, Environmental
Chun-yan Su, Dong Li, Li-jun Wang, Yong Wang
Summary: Ionically conductive hydrogels made from natural ingredients of corn starch and sodium alginate were fabricated using a simple strategy. The hydrogel exhibited excellent mechanical properties and could regain its original shape after compression, twisting, and stretching due to the hydrogen bond and ion crosslinking. By adjusting the calcium ion concentration, the strength and toughness of the hydrogel could be modulated. The conductive hydrogel showed potential for use in wearable electronic devices.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Xiaocheng Wang, Xiaojun Hou, Peiyu Zou, Aimin Huang, Min Zhang, Lin Ma
Summary: This study investigates the controlled release efficacy of nanocomposites based on alginate and bentonite. It was found that (3-chloro-2hydroxypropyl)trimethyl ammonium grafted starch can enhance the swelling property and adsorption capability of the nanocomposites, resulting in a slower release of alachlor.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biophysics
Ting Wang, Wanwan Yi, Yu Zhang, Hang Wu, Hengwei Fan, Jiulong Zhao, Shige Wang
Summary: In recent years, the healing of chronic wounds has become a challenging problem in clinical practice. This study aimed to address the challenges in wound care by designing a dual-network hydrogel composed of sodium alginate and platelet-rich plasma. The hydrogel showed a three-dimensional network structure and exhibited the potential for cell proliferation and vascular regeneration. When applied to wound skin in rats, the hydrogel effectively promoted wound closure. Overall, this strategy offers a simple and feasible approach for overcoming the shortcomings of conventional wound dressings.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Applied
Ganzhe Mao, Shuya Tian, Yanxia Shi, Jiahui Yang, Haiying Li, Hongbo Tang, Wenzhi Yang
Summary: In this study, a novel sodium alginate-arginine-zinc ion (SA-Arg-Zn2+) hydrogel was developed for skin wound dressings. The hydrogel showed high swelling ability, antioxidative activity, and strong antibacterial properties. The wound healing efficacy of SA-Arg-Zn2+ hydrogel was superior to other dressings, with a wound closure ratio of 100% on the 14th day. Additionally, the hydrogel down-regulated inflammatory factors and promoted the production of growth factors. Overall, SA-Arg-Zn2+ hydrogel is an effective and promising wound dressing material.
CARBOHYDRATE POLYMERS
(2023)
Article
Polymer Science
Muhammad Zahid, Maria Lodhi, Ayesha Afzal, Zulfiqar Ahmad Rehan, Muzzamil Mehmood, Talha Javed, Rubab Shabbir, Dorota Siuta, Fayez Althobaiti, Eldessoky S. Dessok
Summary: This study synthesized a wound-healing hydrogel based on radish seeds and demonstrated its effectiveness in healing cutaneous lesions. The higher the concentration of radish seed extract, the better the healing effect.
Article
Biochemistry & Molecular Biology
Jinhua Chi, Ai Li, Mingyu Zou, Shuo Wang, Chenqi Liu, Rui Hu, Zhiwen Jiang, Wanshun Liu, Rongju Sun, Baoqin Han
Summary: In this study, dopamine was successfully grafted with oxidized sodium alginate to fabricate OSA-DA hydrogels with enhanced biocompatibility and suitable adhesion. The hydrogels exhibited appropriate swelling ratio and adhesion characteristics, and demonstrated satisfactory cytocompatibility in cells and biocompatibility in animals. Moreover, OSA-DA hydrogels showed remarkable promoting effects on angiogenesis and wound healing, making them a potential clinical wound dressing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Naglaa Salem El-Sayed, Naiera M. Helmy, Samir Kamel
Summary: Some wound dressings on the market can cause skin tearing and bleeding when removed, making it difficult to treat infected wounds in patients with sensitive skin. In this study, a biocompatible hydrogel loaded with antibiotic and self-healing properties was developed. The hydrogel showed good biocompatibility and strong antibacterial effects against various bacterial strains. Rheological analysis revealed that the hydrogel behaved as a non-Newtonian fluid, suggesting its potential application in wound healing.
Article
Biotechnology & Applied Microbiology
Bushra Ishfaq, Ikram Ullah Khan, Syed Haroon Khalid, Sajid Asghar
Summary: In this study, sodium alginate-based hydrogel films loaded with Betula utilis bark extract were successfully developed and evaluated for their wound healing activity. The optimized formulation exhibited good extract loading capacity, large zone of inhibition against bacteria, and significant wound contraction and reepithelization. The extract-loaded hydrogel dressing showed great potential for cutaneous wound healing.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wenpeng Zhao, Bing Huang, Lei Zhu, Xianqi Feng, Jun Xu, Hao Zhang, Shouke Yan
Summary: In this study, a hydrogel with high mechanical properties, self-healing ability, and conductivity was constructed using starch and natural rubber latex through a simple heating process. The hydrogel can be used as a wearable sensor to monitor human motions with high gauge factor and good durability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Xuecui Song, Jing Guo, Yuanfa Liu, Feng Li, Qiang Yang, Fucheng Guan, Chunqiu Di
Summary: The ionically cross-linked SA/AKP/PAM hydrogel demonstrates unique structure and properties, including excellent mechanical strength and ionic conductivity. Furthermore, it can be used as a capacitive pen and promotes the adhesion and growth of Schwann cells, showing broad prospects for application.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Nanoscience & Nanotechnology
Sunaina Kaul, Poonam Sagar, Ritika Gupta, Priyanka Garg, Nitesh Priyadarshi, Nitin Kumar Singhal
Summary: This study explores the use of nanostructure-conjugated hydrogel as a flexible dressing against multidrug resistant bacterial infections. The results show that the nanostructure-conjugated hydrogel is effective in killing Pseudomonas aeruginosa and Escherichia coli, with slightly lower efficacy against Staphylococcus aureus. In addition, animal experiments demonstrate that the use of nanostructure-conjugated hydrogel in wound treatment can significantly reduce wound size and promote wound healing and tissue regeneration.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Polymer Science
Sana Saeed, Kashif Barkat, Muhammad Umer Ashraf, Maryam Shabbir, Irfan Anjum, Syed Faisal Badshah, Muhammad Aamir, Nadia Shamshad Malik, Akash Tariq, Riaz Ullah
Summary: A hydrogel topical patch of neomycin was developed using sodium alginate (SA) and hydroxyethylcellulose (HEC) as polymers, with free radical polymerization. The pH-sensitive and sol-gel properties of the hydrogels were characterized, and the swelling behavior was evaluated. The hydrogel-based polymeric matrix showed a rough structure that enhanced fluid uptake, and the reaction resulted in a new polymeric network. The hydrogel patches exhibited thermodynamic stability and pH-dependent swelling behavior, with zero-order drug release kinetics. The patches effectively healed wounds on rabbit skin without causing irritation. Neomycin hydrogel patches have potential for controlled delivery in wound healing.
Article
Polymer Science
Haifa Alharbi, Noof A. A. Alenazi, Awatif R. Z. Almotairy, Sahar Sallam, Kholood Alkhamis, Khaled F. F. Alshammari, Nashwa M. M. El-Metwaly
Summary: Photochromic inks have many drawbacks, while self-healable inks are highly photostable and durable. Ultraviolet-stimulated photochromic hydrogels with self-healing characteristics were used to create an authentication stamp. The development of an organic-inorganic hybrid hydrogel ink using lanthanide-doped aluminate nanoparticles and cellulose nanofibers enhanced the mechanical strength and transparency of the prints.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2023)
Article
Chemistry, Applied
Song Cui, David Julian McClements, Jiangli Shi, Xingfeng Xu, Fangjie Ning, Chaoran Liu, Liyang Zhou, Qingjie Sun, Lei Dai
Summary: In this study, low-fat PKEGs were successfully fabricated using zein/phytic acid complex nanoparticles. These PKEGs, with their semi-solid textures and high stability, could serve as effective delivery systems for hydrophobic bioactive substances.
Article
Chemistry, Applied
Xiaoyu Chen, Chaofan Wang, Xiaoyang He, Yang Qin, Lei Dai, Liu Xiong, Tao Wang, Rui Shi, Na Ji, Qingjie Sun
Summary: This study examined the physicochemical properties of potato starch-sodium stearoyl lactylate (SSL) complexes formed by annealing potato starch with 0.6% SSL in different ethanol solutions. The complexes showed higher iodine binding capacity and thermal stability, as well as decreased swelling power and solubility of starch granules. The results suggest that the starch-SSL complexes have potential applications in high-temperature processed foods.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Kaili Qin, Daiyong Sun, Chaofan Wang, Na Ji, Lei Dai, Yang Qin, Liu Xiong, Tao Wang, Qingjie Sun
Summary: By encapsulating starch in chitosan-sodium phytate capsules, the digestion of starch can be delayed, leading to lower blood glucose levels. The study found that the capsules had lower swelling degree than native starch at different temperatures, and contained higher levels of slowly digestible starch and resistant starch. These findings are significant for patients with chronic diseases.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Zhenyu Yang, Jiakai Yan, Yanhua Duan, Lei Dai, Yanfei Wang, Qingjie Sun, David Julian McClements, Xingfeng Xu
Summary: This study successfully fabricated hydrolyzed rice glutelin (HRG) nanoparticles induced by different concentrations of ethanol and investigated their interfacial and stability properties. The results showed that nanoparticles induced by ethanol with the concentration of 50% and 75% exhibited more viscous interfacial film, with 50% emulsion demonstrating better storage stability. Curcumin-loaded HRG50-Pickering emulsion exhibited higher photochemical stability but lower FFAs release and bioaccessibility.
FOOD HYDROCOLLOIDS
(2023)
Article
Biochemistry & Molecular Biology
Xiaoyang He, Shuangshuang Zhao, Zhao Zhang, Lei Dai, Yang Qin, Na Ji, Liu Xiong, Rui Shi, Qingjie Sun
Summary: This study developed a new strategy for producing starch straws with desirable properties using extrusion, retrogradation, and sodium trimetaphosphate (STMP) cross-linking. The cross-linked straws showed higher stiffness and thermal stability compared to the controls. The findings suggest a potential way to produce biodegradable straws from starch while addressing plastic pollution problems.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Song Cui, Zhenyu Yang, David Julian McClements, Xingfeng Xu, Xin Qiao, Liyang Zhou, Qingjie Sun, Bo Jiao, Qiang Wang, Lei Dai
Summary: This study examined the possibility of improving the performance of Pickering emulsions by using a combination of colloidal particles and small molecular emulsifiers. The sequence of emulsifier addition significantly influenced the interfacial structure and properties of the emulsions. The Q-ZP addition sequence was found to be the most effective at forming stable Pickering emulsions with improved functional performance in food applications.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Xiaotong Bu, Minghang Guan, Lei Dai, Na Ji, Yang Qin, Xingfeng Xu, Liu Xiong, Rui Shi, Qingjie Sun
Summary: In this study, large-scale emulsion gel beads were fabricated using an inverse emulsion gelation technique, with dual loading of proanthocyanidin and curcumin achieved by simple starch retrogradation. Increasing the starch concentration resulted in higher hardness and lower swelling ratio of the gel beads under different treatment conditions. Furthermore, the starch-based emulsion gel beads showed a lower release ratio of proanthocyanidins and curcumin in simulated gastric fluid, indicating their tolerance to the gastric environment. However, when the starch gel network was disrupted in simulated intestinal fluid, a large amount of proanthocyanidins and curcumin were released from the beads. Therefore, starch-based emulsion gel beads are ideal carriers for loading hydrophilic and hydrophobic active ingredients.
FOOD HYDROCOLLOIDS
(2023)
Article
Biochemistry & Molecular Biology
Mengting Yu, Lu Yang, Limei Yan, Tao Wang, Yanfei Wang, Yang Qin, Liu Xiong, Rui Shi, Qingjie Sun
Summary: The objective of this study was to create superhydrophobic chitosan films by coating them with zinc oxide nanoparticles and hydrophobic modification with stearic acid. A superhydrophobic film with a contact angle of 156 degrees was achieved by using a 1% concentration of zinc oxide nanoparticles and a 1% concentration of stearic acid, which was due to the combination of micro/nano-level hierarchical structure and low surface energy modification. The superhydrophobic chitosan film demonstrated excellent acid, alkali, heat, and UV stability, as well as a 14.4% reduction in light transmittance at 354 nm. It also exhibited remarkable self-cleaning and oil-water separation performance. Our findings will broaden the application of chitosan films in areas such as food packaging, outdoor self-cleaning materials, and oil-water separations.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Food Science & Technology
Congli Cui, Lin Gao, Lei Dai, Na Ji, Yang Qin, Rui Shi, Yuanyuan Qiao, Liu Xiong, Qingjie Sun
Summary: Food packaging materials are essential for maintaining food quality by preventing deterioration, dehydration, and oxidation. Natural biopolymers, such as polysaccharides and proteins, are being investigated for their potential as hydrophobic films in food packaging. Effective preparation strategies, mechanical and barrier properties, pH responsiveness, self-cleaning performance, and antibacterial and antioxidant functions of hydrophobic biopolymer-based films are summarized. The most effective methods include electrospinning with hydrophobically modified biopolymers, addition of micro/nanofillers and hydrophobic compounds, and hydrophobic modification of the films, which can even produce superhydrophobic films with excellent barrier properties. The current opportunities and challenges of hydrophobic biopolymer-based films are discussed.
FOOD ENGINEERING REVIEWS
(2023)
Article
Food Science & Technology
Qing Liu, Lin Gao, Yang Qin, Na Ji, Lei Dai, Liu Xiong, Qingjie Sun
Summary: The hydrophobicity of corn starch films was improved by adding a new type of covalently formed, oxidized debranched starch/chitosan nanoparticles (SC-NPs). SC-NPs were obtained by a Schiff-base crosslinking reaction between the aldehyde group of dialdehyde debranched starch and the amino group of chitosan. The films reinforced with 3% SC-NPs showed greater water contact angles and improved barrier properties compared to pure starch films.
FOOD PACKAGING AND SHELF LIFE
(2023)
Article
Engineering, Chemical
Xin Qiao, Fudi Liu, Zhihao Kong, Zhenyu Yang, Lei Dai, Yanfei Wang, Qingjie Sun, David Julian McClements, Xingfeng Xu
Summary: This study introduces a heat-assisted pH-shifting (HP) method to prepare pea protein nanoparticles (PNPs) for stabilizing oil-in-water Pickering emulsion gel. The results show that increasing the pH-shifting temperature leads to changes in the structure and interfacial properties of PNPs, and the resulting emulsion gel exhibits improved stability and bioaccessibility.
JOURNAL OF FOOD ENGINEERING
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
