Article
Metallurgy & Metallurgical Engineering
Di Mei, Cheng Wang, Sviatlana Lamaka, Mikhail L. Zheludkevich
Summary: Albumin accelerates the corrosion of CP Mg in HBSS initially but slows down degradation afterwards. It decreases the concentration of free Ca2+ in HBSS and delays the formation of protective co-precipitation products on the Mg surface. The pH buffering effect of albumin is illustrated through comparison of local and bulk pH values during the immersion period.
JOURNAL OF MAGNESIUM AND ALLOYS
(2021)
Article
Chemistry, Physical
Piotr Prochor, Zaneta Anna Mierzejewska
Summary: Scientists have identified two main paths for orthopedic implant fabrication, either searching for new materials with properties closest to natural bone or creating individually adapted geometry with Rapid Prototyping methods. PEEK GRF30 and Ti6Al4V SLM are materials of interest, but further research is needed to fully understand their bioactivity. The study found that both materials exhibited bioactivity comparable to Ti6Al4V, showing promising potential for orthopedic implants.
Article
Medicine, General & Internal
Pratima Panda, Shashirekha Govind, Sanjit Kumar Sahoo, Satabdi Pattanaik, Rachappa M. Mallikarjuna, Triveni Nalawade, Sanjay Saraf, Naseer Al Khaldi, Salma Al Jahdhami, Vinay Shivagange, Amit Jena
Summary: The study examined the effects of different pulp capping agents on human dental pulp stem cells. The results showed that platelet-rich fibrin (PRF) had the highest cell viability and the greatest potential to enhance cell proliferation and differentiation. On the other hand, Tetric N-Bond was found to be ineffective as a pulp capping agent. Overall, PRF was the most effective in maintaining the viability of human dental pulp stem cells compared to the other tested materials.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Shankargouda Patil, Ahmed Alamoudi, Bassam Zidane, Khalid J. Alzahrani, Fuad M. Alzahrani, Hamsa Jameel Banjer, Rodolfo Reda, Thodur Madapusi Balaji, Shilpa Bhandi, A. Thirumal Raj, Luca Testarelli
Summary: This study investigated the effects of melatonin on the proliferation and differentiation of dental pulp stem cells (DPSCs). The results showed that melatonin at concentrations of 1 μM and 25 μM stimulated the differentiation of DPSCs into osteocytes, but had little influence on adipogenic and chondrogenic differentiation.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Health Care Sciences & Services
Nezar Boreak, Ahmed Alkahtani, Khalid Alzahrani, Amani Hassan Kenani, Wafa Hussain Faqehi, Hadeel Hussain Faqehi, Raghad Essa Ageeli, Wafa Nasser Moafa, Hosam Ali Baeshen, Shilpa Bhandi, Zohaib Khurshid, Vikrant R. Patil, Luca Testarelli, Shankargouda Patil
Summary: The study investigated the effects of Cordycepin on dental pulp-derived mesenchymal stem cells, revealing that lower concentrations did not affect cell viability, had some impact on proliferation, influenced the cell cycle, and affected migratory ability in a concentration-dependent manner.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Health Care Sciences & Services
Shilpa Bhandi, Shankargouda Patil, Nezar Boreak, Hitesh Chohan, Abdulaziz S. AbuMelha, Mazen F. Alkahtany, Khalid H. Almadi, Thilla Sekar Vinothkumar, A. Thirumal Raj, Luca Testarelli
Summary: Different intracanal medicaments have varying effects on the viability and survival of dental pulp stem cells at different doses and exposure times. Calcium hydroxide and triamcinolone promote cell viability, while doxycycline, potassium iodide, and glutaraldehyde increase cell death.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Health Care Sciences & Services
Hytham N. Fageeh, Shilpa Bhandi, Mohammed Mashyakhy, Ahmed Al Kahtani, Zahi Badran, Deepak Mehta, Hammam Ibrahim Fageeh, Thodur Madapusi Balaji, Hosam Ali Baeshen, Saranya Varadarajan, A. Thirumal Raj, Vikrant R. Patil, Nishant Vyas, Alessio Zanza, Luca Testarelli, Shankargouda Patil
Summary: The study assessed the potential of quercetin-induced living cell constructs derived from dental pulp stem cells for soft tissue augmentation. The induced constructs showed good handling properties and exhibited characteristics of cells embedded in tissue matrix, along with increased expression of stemness-related genes.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Cell Biology
Kyu Hwan Kwack, Hyeon-Woo Lee
Summary: Dental caries is a common disease that causes damage to teeth and pulp tissue. Dental pulp stem cells have multipotency, high proliferation rate, and immunosuppressive properties, making them ideal for regenerating damaged pulp tissue.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Yingjie Bai, Yimeng Niu, Shengao Qin, Guowu Ma
Summary: This article introduces the preparation process, surface structure, and application forms of acemannan (AC), a natural polysaccharide extracted from Aloe vera. AC has excellent immunomodulatory, antiviral, antitumor, and tissue regeneration effects, and has been widely used in tissue regenerative medicine. The combination of AC and other compounds has been shown to produce composite products with excellent biological and physical properties and has broader research prospects.
Article
Biochemistry & Molecular Biology
Duaa Abuarqoub, Nouf Mahmoud, Walhan Alshaer, Marwa Mohammad, Abed Alqader Ibrahim, Mairvat Al-Mrahleh, Mohammad Alnatour, Dana A. Alqudah, Ezaldeen Esawi, Abdalla Awidi
Summary: Gold nanoparticles (AuNPs) have been widely used in biological and biomedical applications. This study evaluated the effects of two different shapes of AuNPs, rods (AuNR-PEG) and spheres (AuNS-PEG), on dental pulp stem cells. The results showed that AuNS-PEG had a stimulatory effect on cell proliferation and lower toxicity compared to AuNR-PEG. Additionally, cells treated with AuNPs and cultured with fetal bovine serum showed higher proliferation rates and lower toxicity compared to serum-free media.
Article
Polymer Science
Bowen Liu, Chenjiao Zhang, Han Zhao, Jian Gao, Jingchao Hu
Summary: This study investigates the correction of PAX9 gene mutation using gene editing technology and chitosan hydrogel. The results show that chitosan hydrogel can efficiently deliver naked DNA into dental pulp stem cells and achieve higher correction efficiency compared to gene replacement. Moreover, the corrected PAX9 gene exhibits enhanced viability, differentiation capacity, and transcriptional activation ability, which has significant implications for treating hypodontia.
Article
Cell & Tissue Engineering
Mohammed Zayed, Koichiro Iohara, Hideto Watanabe, Mami Ishikawa, Michiyo Tominaga, Misako Nakashima
Summary: The study found that hypoxia-preconditioned DPSCs (hpDPSCs) have advantages in proliferation rate and stemness, making them a potential effective source for pulp regeneration.
STEM CELL RESEARCH & THERAPY
(2021)
Article
Food Science & Technology
Maria Carolina Otalora, Andrea Wilches-Torres, Jovanny A. Gomez Castano
Summary: This study demonstrated the potential application of microencapsulated pink guava pulp as a natural colorant for dairy products, showing high content of lycopene, dietary fiber, and antioxidant activity, as well as stable color imparted to yogurt, contrasting with synthetic colorants.
Article
Cell Biology
Edward J. Calabrese, Evgenios Agathokleous, Gaurav Dhawan, Rachna Kapoor, Vittorio Calabrese
Summary: This study represents the first assessment of hormetic dose responses by human dental pulp stem cells, focusing on cell renewal and differentiation. The study found that hormetic dose responses are commonly observed in this model, involving a wide range of chemicals including pharmaceuticals, dietary supplements/extracts from medicinal plants, and endogenous agents. The study evaluated the mechanistic foundations, study design considerations, and therapeutic implications of the hormetic dose responses in hDPSCs.
AGEING RESEARCH REVIEWS
(2022)
Review
Immunology
Fenyao Li, Xinxin Wang, Jin Shi, Shuting Wu, Wenbo Xing, Yan He
Summary: Dental pulp stem cells have strong immunomodulatory capabilities and can be used to treat inflammation-related diseases and autoimmune disorders. The mechanism of action is complex and may involve the regulation of immune cells through inflammatory immune-related signaling pathways.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Polymer Science
Mohadeseh Rezaei, Nahid Hassanzadeh Nemati, Davood Mehrabani, Ali Komeili
Summary: "The incorporation of CUC in the scaffold enhanced elasticity and antibacterial properties, while also improving cell viability and attachment to the scaffold in skin tissue engineering."
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Materials Science, Textiles
Mohadeseh Rezaie, Nahid Hassanzadeh Nemati, Davood Mehrabani, Ali Komeili
Summary: This study investigated the elasticity, degradation, and mechanical strength of SCMC and CA-based scaffolds, as well as their effects on fibroblasts. The results showed that the SCMC/CA nanofiber scaffolds had favorable properties for skin tissue engineering applications, with high porosity, elasticity, and biological compatibility.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Public, Environmental & Occupational Health
Parisa Soltan-Alinejad, Hamzeh Alipour, Aboozar Soltani, Qasem Asgari, Amin Ramezani, Davood Mehrabani, Kourosh Azizi
Summary: This study characterized and cloned the PLA(2) enzyme called Maurolipin from Iranian Scorpio maurus venom. In silico analyses revealed the difference in genetic and protein structures of PLA(2) based on scorpion species and geographical conditions.
JOURNAL OF TROPICAL MEDICINE
(2022)
Article
Respiratory System
Shahin Kavousi, Hossein Akbarialiabad, Davood Mehrabani, Alireza Mohamadian, Aria Ghahramani, Ali Shirkhoda, Reza Jalli
Summary: In survivors exposed to Sulfur Mustard, patients with bronchiectasis and lung fibrosis have a significantly higher risk of developing lung cancers, necessitating close follow-up of these victims.
BMC PULMONARY MEDICINE
(2022)
Article
Medicine, General & Internal
Reza Jalli, Davood Mehrabani, Shahrokh Zare, Mahdi Saeedi Moghadam, Iman Jamhiri, Navid Manafi, Golshid Mehrabani, Janan Ghabanchi, Iman Razeghian Jahromi, Aghdass Rasouli-Nia, Feridoun Karimi-Busheri
Summary: This study assessed the tracking of iron oxide-labeled stem cells transfected by lipofectamine using magnetic resonance imaging (MRI) in vitro and in vivo. Rat dental pulp stem cells (DPSCs) were characterized, labeled with iron oxide nanoparticles, and then transfected with lipofectamine. The internalization of the nanoparticles was confirmed by Prussian blue staining and MRI tracking.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Biology
M. Omidi-Shahsavandi, P. Yaghmaei, S. Ahmadian, A. Ebrahim-Habibi
Summary: Silibinin and trans-chalcone were found to have inhibitory effects on insulin amyloid formation, with Silibinin showing a better effect. Animal experiments also showed that these two compounds can reduce amyloid plaque formation and improve cognitive function. Molecular docking experiments provided insights into the binding site of these compounds with insulin.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2023)
Article
Emergency Medicine
Davood Mehrabani, Mehra Nazempour, Rouhollah Mehdinavaz-Aghdam, Seyedeh-Sara Hashemi, Reza Jalli, Mahdi Saeedi Moghadam, Shahrokh Zare, Iman Jamhiri, Javad Moayedi, Feridoun Karimi-Busheri
Summary: This study demonstrates that SPION labeling coupled with MRI can be used to track the fate of stem cells after transplantation in a burn model.
Review
Parasitology
Zahra Nasiri, Mohsen Kalantari, Jalal Mohammadi, Salman Daliri, Davood Mehrabani, Kourosh Azizi
Summary: This study reviewed the epidemiology, reservoirs, vectors, and climatic factors of cutaneous leishmaniasis (CL) in Iran. The prevalence of CL was found to be high in western Iran and has spread to the central and southern regions in recent years. Certain regions in southern Iran are notable hotspots for CL due to the presence of potential rodent hosts. Molecular identification using genomic diagnosis revealed heterogeneity in leishmaniasis across different parts of the country.
Article
Medicine, Research & Experimental
Kamyar Iravani, Davood Mehrabani, Aida Doostkam, Negar Azarpira, Pooya Iranpour, Mohsen Bahador, Soheila Mehravar
Summary: The study evaluated the efficacy of adipose tissue-derived mesenchymal stem cells (ASCs) on cartilaginous regeneration in an experimental rabbit model. The results showed that ASCs significantly increased cartilage regeneration, reduced inflammation, and fibrosis. Magnetic resonance imaging was proven to be a useful, noninvasive method for tracking correct ASCs placement and viability in cartilage regeneration.
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
(2022)
Article
Pharmacology & Pharmacy
Leyla Anari, Davood Mehrabani, Mahboobeh Nasiri, Shahrokh Zare, Iman Jamhiri, Jason P. Acker
Summary: This study investigated the effect of methamphetamine on proliferation, differentiation, and apoptosis of human adipose tissue stem cells. The findings showed that methamphetamine decreased the proliferation and differentiation properties of the stem cells, while increasing apoptosis.
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
(2022)
Article
Medicine, General & Internal
Farshid Parsa, Seyed Ebrahim Hoseini, Davood Mehrabani, Seyedeh Sara Hashemi
Summary: The study found that cannabis use can result in memory reduction, decreased expression of Bcl-2 gene, increased expression of Bax gene, and significant increase in inflammatory cytokines.
Article
Medicine, General & Internal
Azita Azad, Alireza Ranjbaran, Zahra Zareshahrabadi, Davood Mehrabani, Maryam Zahed Zahedani, Asana Talebanpour, Kamiar Zomorodian
Summary: The study revealed that S. thermophilus has inhibitory effects on the growth and biofilm formation of C. albicans, in a dose-dependent manner. In a mouse model, S. thermophilus significantly reduced colony-forming units in mice receiving probiotic treatment, indicating its potential use in managing oral candidiasis.
IRANIAN JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Medicine, General & Internal
Hosein Rasekh, Davood Mehrabani, Mehdi Hosseini Farahi, Seyed Jalil Masoumi, Jason P. Acker
Summary: The acetonic extract of Feijoa fruit showed no cytotoxic effects on human bone marrow stem cells at certain doses, promoting cell proliferation until day 4 and inducing apoptosis afterwards. This study indicates that Feijoa may possess antioxidant, anti-inflammatory, and modulatory activities.
ELECTRONIC JOURNAL OF GENERAL MEDICINE
(2021)
Article
Surgery
Fariba Jaafari-Sheybani, Seyed-Ebrahim Hosseini, Davood Mehrabani, Amin Derakhshanfar, Feridoun Karimi-Busheri
Summary: This study demonstrated that METH use in experimental rats led to increased anxiety levels and histological inflammation, degeneration, and necrosis in adipose tissue, highlighting the dangers of recreational METH use for weight loss purposes.
WORLD JOURNAL OF PLASTIC SURGERY
(2021)
Article
Surgery
Seyedeh-Sara Hashemi, Mahdukht Mahmoodi, Hamid Reza Tohidinik, Ali Akbar Mohammadi, Davood Mehrabani
Summary: This study evaluated the epidemiology of burn and LA50 in children in Shiraz, Southern Iran from 2012 to 2016. The findings showed that male patients were more than females, but the mortality rate was higher in females. Additionally, scald and flame were the most common causes of burn.
WORLD JOURNAL OF PLASTIC SURGERY
(2021)
