CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus

Stress-tolerant non-conventional microbes enable next-generation chemical biosynthesis

(2020) Sarah Thorwall et al.   Nature Chemical Biology

A genetic toolbox for metabolic engineering of Issatchenkia orientalis

(2020) Mingfeng Cao et al.   METABOLIC ENGINEERING

Metabolic Engineering of Saccharomyces cerevisiae for Rosmarinic Acid Production

(2020) Mahsa Babaei et al.   ACS Synthetic Biology

Engineering Yarrowia lipolytica as a Chassis for De Novo Synthesis of Five Aromatic-Derived Natural Products and Chemicals

(2020) Yang Gu et al.   ACS Synthetic Biology

Synthesis of polyketides from low cost substrates by the thermotolerant yeast Kluyveromyces marxianus

(2019) Tami L. McTaggart et al.   BIOTECHNOLOGY AND BIOENGINEERING

Biological Parts for Kluyveromyces marxianus Synthetic Biology

(2019) Arun S. Rajkumar et al.   Frontiers in Bioengineering and Biotechnology

Building microbial factories for the production of aromatic amino acid pathway derivatives: From commodity chemicals to plant-sourced natural products

(2019) Mingfeng Cao et al.   METABOLIC ENGINEERING

Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica

(2019) Cory Schwartz et al.   METABOLIC ENGINEERING

De novo biosynthesis of 2-phenylethanol in engineered Pichia pastoris

(2019) Sijia Kong et al.   ENZYME AND MICROBIAL TECHNOLOGY

Connecting central carbon and aromatic amino acid metabolisms to improve de novo 2-phenylethanol production in Saccharomyces cerevisiae

(2019) Else-Jasmijn Hassing et al.   METABOLIC ENGINEERING

Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii

(2019) Neil C. Dalvie et al.   ACS Synthetic Biology

Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose

(2018) Cory Schwartz et al.   Biotechnology Journal

CRISPR-mediated Genome Editing and Gene Repression in Scheffersomyces stipitis

(2018) Mingfeng Cao et al.   Biotechnology Journal

Metabolic Engineering of Escherichia coli for Production of 2-Phenylethanol and 2-Phenylethyl Acetate from Glucose

(2018) Daoyi Guo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Iterative algorithm-guided design of massive strain libraries, applied to itaconic acid production in yeast

(2018) Eric M. Young et al.   METABOLIC ENGINEERING

Multiplexed CRISPR Activation of Cryptic Sugar Metabolism Enables Yarrowia Lipolytica Growth on Cellobiose

(2018) Cory Schwartz et al.   Biotechnology Journal

CRISPR-mediated Genome Editing and Gene Repression in Scheffersomyces stipitis

(2018) Mingfeng Cao et al.   Biotechnology Journal

Highly Multiplexed CRISPRi Repression of Respiratory Functions Enhances Mitochondrial Localized Ethyl Acetate Biosynthesis in Kluyveromyces marxianus

(2018) Ann-Kathrin Löbs et al.   ACS Synthetic Biology

Ethyl acetate production by the elusive alcohol acetyltransferase from yeast

(2017) Aleksander J. Kruis et al.   METABOLIC ENGINEERING

Multilevel engineering of the upstream module of aromatic amino acid biosynthesis in Saccharomyces cerevisiae for high production of polymer and drug precursors

(2017) Miguel Suástegui et al.   METABOLIC ENGINEERING

Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strain

(2017) Yumiko Nambu-Nishida et al.   Scientific Reports

High throughput, colorimetric screening of microbial ester biosynthesis reveals high ethyl acetate production fromKluyveromyces marxianuson C5, C6, and C12 carbon sources

(2016) Ann-Kathrin Löbs et al.   Biotechnology Journal

Overexpressing enzymes of the Ehrlich pathway and deleting genes of the competing pathway in Saccharomyces cerevisiae for increasing 2-phenylethanol production from glucose

(2016) Li Shen et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica

(2016) Cory Schwartz et al.   ACS Synthetic Biology

Innovating a Nonconventional Yeast Platform for Producing Shikimate as the Building Block of High-Value Aromatics

(2016) Meirong Gao et al.   ACS Synthetic Biology

High throughput, colorimetric screening of microbial ester biosynthesis reveals high ethyl acetate production fromKluyveromyces marxianuson C5, C6, and C12 carbon sources

(2016) Ann-Kathrin Löbs et al.   Biotechnology Journal

Genetic basis of the highly efficient yeast Kluyveromyces marxianus: complete genome sequence and transcriptome analyses

(2015) Noppon Lertwattanasakul et al.   Biotechnology for Biofuels

Establishment of a yeast platform strain for production of p- coumaric acid through metabolic engineering of aromatic amino acid biosynthesis

(2015) Angelica Rodriguez et al.   METABOLIC ENGINEERING

Biosynthesis of 2-phenylethanol from glucose with genetically engineered Kluyveromyces marxianus

(2014) Tae-Yeon Kim et al.   ENZYME AND MICROBIAL TECHNOLOGY

Effect of oxygenation and temperature on glucose-xylose fermentation in Kluyveromyces marxianus CBS712 strain

(2014) Lorenzo Signori et al.   Microbial Cell Factories

Dual N- and C-Terminal Helices Are Required for Endoplasmic Reticulum and Lipid Droplet Association of Alcohol Acetyltransferases in Saccharomyces cerevisiae

(2014) Jyun-Liang Lin et al.   PLoS One

Simultaneous integration of multiple genes into the Kluyveromyces marxianus chromosome

(2013) Paul Heo et al.   JOURNAL OF BIOTECHNOLOGY

Putting bugs to the blush

(2013) Philana V van Summeren-Wesenhagen et al.   Bioengineered

Characterization of Saccharomyces cerevisiae promoters for heterologous gene expression in Kluyveromyces marxianus

(2012) Ki-Sung Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Functional characterization of rose phenylacetaldehyde reductase (PAR), an enzyme involved in the biosynthesis of the scent compound 2-phenylethanol

(2010) Xiao-Min Chen et al.   JOURNAL OF PLANT PHYSIOLOGY

Kluyveromyces marxianus: A yeast emerging from its sister's shadow

(2010) Melanie M. Lane et al.   Fungal Biology Reviews

High-temperature fermentation: how can processes for ethanol production at high temperatures become superior to the traditional process using mesophilic yeast?

(2009) Babiker M. A. Abdel-Banat et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bioproduction of the aroma compound 2-Phenylethanol in a solid-liquid two-phase partitioning bioreactor system byKluyveromyces marxianus

(2009) Fang Gao et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-Temperature Ethanol Fermentation and Transformation with Linear DNA in the Thermotolerant Yeast Kluyveromyces marxianus DMKU3-1042

(2008) S. Nonklang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Super life - how and why ‘cell selection’ leads to the fastest-growing eukaryote

(2008) Philip Groeneveld et al.   FEBS Journal

Alleviation of feedback inhibition in Saccharomyces cerevisiae aromatic amino acid biosynthesis: Quantification of metabolic impact

(2008) M.A.H. Luttik et al.   METABOLIC ENGINEERING

Metabolic engineering delivers next-generation biofuels

(2008) Jay D Keasling et al.   NATURE BIOTECHNOLOGY