Melatonin prevents LPS-induced epithelial-mesenchymal transition in human alveolar epithelial cells via the GSK-3β/Nrf2 pathway
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Title
Melatonin prevents LPS-induced epithelial-mesenchymal transition in human alveolar epithelial cells via the GSK-3β/Nrf2 pathway
Authors
Keywords
Melatonin, Lipopolysaccharide, Epithelial-mesenchymal transition, Oxidative stress, Lung fibrosis, Nrf2
Journal
BIOMEDICINE & PHARMACOTHERAPY
Volume 132, Issue -, Pages 110827
Publisher
Elsevier BV
Online
2020-10-13
DOI
10.1016/j.biopha.2020.110827
References
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- (2018) Guo-Yu Zhang et al. Oxidative Medicine and Cellular Longevity
- Intranasal Delivery of Copper Oxide Nanoparticles Induces Pulmonary Toxicity and Fibrosis in C57BL/6 mice
- (2018) Xiaofeng Lai et al. Scientific Reports
- Oxidative stress-driven pulmonary inflammation and fibrosis in a mouse model of human ataxia-telangiectasia
- (2018) Ruth Duecker et al. Redox Biology
- Polydatin attenuates reactive oxygen species-induced airway remodeling by promoting Nrf2-mediated antioxidant signaling in asthma mouse model
- (2018) Haizhu Zeng et al. LIFE SCIENCES
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- (2018) Vinícius Rosa Oliveira et al. JOURNAL OF BIOMECHANICS
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- (2017) Lawei Yang et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo
- (2017) Lvyi Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melatonin successfully rescues hippocampal bioenergetics and improves cognitive function following drug intoxication by promoting Nrf2-ARE signaling activity
- (2017) Li-You Chen et al. JOURNAL OF PINEAL RESEARCH
- Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis
- (2017) Hongming Lv et al. Redox Biology
- Melatonin attenuates TGFβ1-induced epithelial-mesenchymal transition in lung alveolar epithelial cells
- (2016) Na Yu et al. Molecular Medicine Reports
- Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis
- (2016) Wencheng Zhou et al. Scientific Reports
- Dual regulation of transcription factor Nrf2 by Keap1 and by the combined actions of β-TrCP and GSK-3
- (2015) John D. Hayes et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Resveratrol ameliorates lipopolysaccharide-induced epithelial mesenchymal transition and pulmonary fibrosis through suppression of oxidative stress and transforming growth factor-β1 signaling
- (2015) Yun-Qian Zhang et al. CLINICAL NUTRITION
- Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis
- (2015) Leandro da Silva Borges et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as a preventive and curative therapy against pulmonary hypertension
- (2015) Gerald Maarman et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable
- (2015) Lucien C. Manchester et al. JOURNAL OF PINEAL RESEARCH
- Mouse Models of Acute Respiratory Distress Syndrome
- (2015) Famke Aeffner et al. TOXICOLOGIC PATHOLOGY
- Involvement of Nrf2-GSH signaling in TGFβ1-stimulated epithelial-to-mesenchymal transition changes in rat renal tubular cells
- (2014) In-geun Ryoo et al. ARCHIVES OF PHARMACAL RESEARCH
- Selenium Suppresses Lipopolysaccharide-Induced Fibrosis in Peritoneal Mesothelial Cells Through Inhibition of Epithelial-to-Mesenchymal Transition
- (2014) Jinyan Liu et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Protective effects of melatonin and quercetin on experimental lung injury induced by carbon tetrachloride in rats
- (2014) Elif Taslidere et al. EXPERIMENTAL LUNG RESEARCH
- Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism
- (2014) Ke Ding et al. FREE RADICAL BIOLOGY AND MEDICINE
- Induction of ROS-Dependent Mitochondria-Mediated Intrinsic Apoptosis in MDA-MB-231 Cells by Glycoprotein from Codium decorticatum
- (2014) Ramar Thangam et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Melatonin feedback on clock genes: a theory involving the proteasome
- (2014) Jerry Vriend et al. JOURNAL OF PINEAL RESEARCH
- Systemic combined melatonin-mitochondria treatment improves acute respiratory distress syndrome in the rat
- (2014) Cheuk Kwan Sun et al. JOURNAL OF PINEAL RESEARCH
- Melatonin attenuates hypoxic pulmonary hypertension by inhibiting the inflammation and the proliferation of pulmonary arterial smooth muscle cells
- (2014) Haifeng Jin et al. JOURNAL OF PINEAL RESEARCH
- Cardioprotective effects of melatonin against myocardial injuries induced by chronic intermittent hypoxia in rats
- (2014) Hang-Mee Yeung et al. JOURNAL OF PINEAL RESEARCH
- Melatonin: a well-documented antioxidant with conditional pro-oxidant actions
- (2014) Hong-Mei Zhang et al. JOURNAL OF PINEAL RESEARCH
- Melatonin Antagonizes Mn-Induced Oxidative Injury Through the Activation of Keap1–Nrf2–ARE Signaling Pathway in the Striatum of Mice
- (2014) Yu Deng et al. NEUROTOXICITY RESEARCH
- Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice
- (2014) Hui Zhao et al. PLoS One
- The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
- (2014) John D. Hayes et al. TRENDS IN BIOCHEMICAL SCIENCES
- The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance
- (2013) E. L. Burnham et al. EUROPEAN RESPIRATORY JOURNAL
- Inhibition of airway epithelial-to-mesenchymal transition and fibrosis by kaempferol in endotoxin-induced epithelial cells and ovalbumin-sensitized mice
- (2013) Ju-Hyun Gong et al. LABORATORY INVESTIGATION
- Toll-like receptor 4 signaling promotes epithelial-mesenchymal transition in human hepatocellular carcinoma induced by lipopolysaccharide
- (2012) Ying-Ying Jing et al. BMC Medicine
- Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism
- (2012) Marta R. Gorowiec et al. FREE RADICAL BIOLOGY AND MEDICINE
- Resveratrol inhibits LPS-induced epithelial-mesenchymal transition in mouse melanoma model
- (2012) Man-Chin Chen et al. Innate Immunity
- Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis
- (2011) Harold A. Chapman Annual Review of Physiology
- LPS-Induced Epithelial-Mesenchymal Transition of Intrahepatic Biliary Epithelial Cells
- (2010) Lijin Zhao et al. JOURNAL OF SURGICAL RESEARCH
- Response to vasoconstrictor agents by detrusor smooth muscles from cisplatin-treated rats and antioxidant treatment
- (2010) K.E. Atalik et al. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
- Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis
- (2009) Harikrishna Tanjore et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
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