Article
Materials Science, Ceramics
Young Sunwoo, Gopalu Karunakaran, Eun-Bum Cho
Summary: Hollow mesoporous silica nanospheres were synthesized using pentablock copolymer templates under acidic aqueous conditions, with tetraethyl orthosilicate as the silica precursor. The structure could be tuned by using different length pentablock copolymer templates, resulting in variations in pore structure and morphology. The samples demonstrated hydrothermal stability and the formation of hollow mesopore structures under room temperature conditions.
CERAMICS INTERNATIONAL
(2021)
Article
Polymer Science
Tae-Yang Jeong, Young Dong Lee, Yoojung Ban, Juho Lee, Hayeong Lee, Yong Ku Kwon
Summary: By incorporating surface-treated hollow mesoporous silica nanoparticles, the volume shrinkage of wet gels during drying process is avoided, resulting in the formation of a robust network structure of PI hybrid xerogels. The application of PI hybrid xerogel separators in lithium ion batteries shows significantly improved electrolyte uptake and interfacial compatibility compared to traditional PI separators.
Article
Chemistry, Inorganic & Nuclear
Duo Wang, Shixing Han, Xiaohan Dai
Summary: Fluorescent nanoprobe FHMSN, synthesized by functionalizing hollow silica nanospheres with tetraphenylethylene derivatives, selectively detects antibacterial furazolidone in water system. The probe shows quick and sensitive response towards furazolidone and has no significant detection effect towards other water pollutions.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Cell Biology
Jie Shen, Ruihuan Wang, Qing Wang, Minjuan Zhang, Chunyan Liu, Zhenxia Tao, Guohong Su
Summary: Bortezomib-loaded HMSNs (BTZ@HMSNs) system sustains the release of BTZ, inhibits lymphoma cell proliferation and migration, and promotes apoptosis. BTZ@HMSNs downregulate oncogenic genes in lymphoma development, activate p53 signaling, and reduce tumor volume in lymphoma mice model, demonstrating improved tumor-suppressing effect compared to free BTZ. HMSNs show promise as a strategy for delivering therapeutic agents for cancer treatment.
Article
Chemistry, Applied
Zizhu Wang, Mingxi Liu, Kaijie Li, Shenghu Zhou
Summary: In this work, Pt-NixOy@HMSNs heteroaggregate nanoparticles were synthesized, featuring Pt-NixOy hybrid nanoparticles inside hollow cavities of mesoporous silica nanospheres. Different Pt/Ni ratios Pt-NixOy@HMSNs were obtained by adjusting the ratios of Pt2+/Ni2+ in micelles. The obtained Pt4-(NixOy)1/x@HMSNs showed enhanced catalytic performance in the hydrolysis of ammonia borane, attributed to the synergistic effect of Pt-NixOy and void confinement.
MICROPOROUS AND MESOPOROUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Guangyue Shi, Zhongtao Li, Zhichen Zhang, Qiangqiang Yin, Na Li, Shengchao Wang, Guiqiang Qi, Liguo Hao
Summary: In order to improve the efficacy of breast cancer treatment, Paclitaxel was encapsulated in hyaluronic acid modified hollow mesoporous silica. The resulting formulation exhibited enzyme-responsive drug release and showed enhanced accumulation within cancer cells. It also demonstrated significantly greater cytotoxicity and holds promise as a potent candidate for breast cancer therapy.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Ruilin Yuan, Chun Wang, Long Chen, Han Cheng, Wentuan Bi, Wensheng Yan, Yi Xie, Changzheng Wu
Summary: Hollow nanostructures with enclosed or semi-enclosed spaces inside are crucial for intrinsic physicochemical properties. A new configuration of hollow nanostructures with more than three layers of shells and integrated mesopores on every shell has been developed, exhibiting periodic interfaces and abundant mesopores. The thermal conductivity is low due to the suppression of gas molecule convection by boundary scattering. This design provides an ideal platform for studying the influence of nanostructure design on intrinsic physicochemical properties and promotes the development of hollow nanostructures.
Article
Chemistry, Multidisciplinary
Ruyi Wang, Yuhui Zhang, Shichun Gu, Jing Shen, Xue Wang, Yapeng He
Summary: Monodisperse hollow mesoporous silica nanospheres with large cavity (62 nm) in the inner core, small mesopores in the outer shell, and high specific surface area of 373 m(2)/g are successfully synthesized via dual-template synthetic approach. The volume proportion of alcohols in the solution can effectively regulate the architectures of the nanospheres. The prepared hollow mesoporous silica nanospheres demonstrate high loading capacity and favorable selectivity towards anionic dye molecules.
Article
Biochemistry & Molecular Biology
Misun Kang, Jong-tak Lee, Jae Young Bae
Summary: Formaldehyde emitted from household products is harmful to human health. This study compares the formaldehyde adsorption characteristics of mesoporous and mesoporous hollow silicas synthesized with or without a calcination process. The mesoporous hollow silica synthesized without a calcination process has the best adsorption performance, followed by the mesoporous hollow silica synthesized with a calcination process and mesoporous silica. This research demonstrates the potential of mesoporous hollow silica as an effective support for harmful gas adsorption.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Xuwen Guo, Zhichao Chen, Yanping Huang, Hao Lv, Yaru Wang, Lizhi Sun, Kai Song, Ben Liu
Summary: Ternary noble metal-metalloid-nonmetal PdBS alloy mesoporous nanospheres with three-dimensional central-radial pore channels were prepared via precise control in reduction and nucleation growth, showing remarkably improved electrocatalytic performance. This finding extends knowledge on the rational design and targeted synthesis of novel noble metal-metalloid-nonmetal alloys for catalysis and other applications.
INORGANIC CHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Kunpeng Lin, Ying Gan, Peide Zhu, Shanshan Li, Chen Lin, Shuling Yu, Shuang Zhao, Jiahua Shi, Runming Li, Jinfang Yuan
Summary: Various polydopamine nanospheres were synthesized using triblock copolymer Pluronic F127 and 1,3,5-trimethylbenzene as soft templates, allowing for precise morphology control. The H-MPDANSs exhibited excellent drug release properties and photothermal performance.
Article
Chemistry, Multidisciplinary
Chao Peng, Yu Liang, Ning Su, Siwen Chen, Zhen Yuan, Yanqun Chen, Dong Wu, Bin Wu, Yang Zhang, ZiTing Xu, Si Zheng, Yingjia Li, Bingxia Zhao
Summary: Chemo-radiotherapy has significant advantages in treatment and prognosis. This study constructed biodegradable nanoagents that can deliver chemotherapeutics and alleviate hypoxia to enhance chemo-radiotherapy. The nanoagents demonstrated self-activation and on-demand release of the chemotherapeutic drug through stimulation by glutathione (GSH). Moreover, the nanoagents triggered cascade catalytic reactions to alleviate hypoxia and enhanced the chemo-radiotherapy effect. The results suggest that these nanoagents have promising potential for boosting chemo-radiotherapy.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Chemistry, Multidisciplinary
Justine Ben Ghozi-Bouvrande, Stephane Pellet-Rostaing, Sandrine Dourdain
Summary: This study investigates the synthesis of silica-based type I porous liquids by modifying the main synthesis parameters to tune the size of the nanospheres and internal cavities, as well as the silica shell microporosity to control the accessibility of the internal cavities. The key parameters of hollow silica nanospheres for optimized structural and porous properties in the synthesis of type I porous liquids are highlighted in this research.
Article
Chemistry, Multidisciplinary
Li Xu, Min Guo, Chin-Te Hung, Xiao-Lei Shi, Yiwen Yuan, Xingmiao Zhang, Ren-Hua Jin, Wei Li, Qiang Dong, Dongyuan Zhao
Summary: We report a strategy for the synthesis of chiral mesoporous silica nanospheres with molecular-scale-like chirality. The functionalization of micelles with chiral amide gels leads to the growth of molecularly chiral silica sols, which self-assemble into dendritic large mesoporous silica nanospheres with molecular chirality. The resulting chiral mesoporous silica shows abundant large mesopores, high pore volumes, high surface areas, and exhibits notable optical activity. It also displays good chiral stability and exhibits significant inhibition of β-amyloid protein aggregation formation and cytotoxicity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Agriculture, Multidisciplinary
Jing Hu, Peiting Du, Ruoyi Xu, Weijun Deng
Summary: This study fabricated supersmall dendritic mesoporous silica nanospheres (DMSNs) with tunable diameters, serving as nanocarriers for antioxidants and flavoring oils to generate stable emulsions. Gas chromatography-mass spectrometry-olfactometry (GC-MS-O) analysis demonstrated that DMSNs have outstanding protective functionalities for the encapsulated flavoring oil. The research indicates that DMSNs are an ideal platform for stable Pickering emulsions for aromatic compounds, offering a new approach for delivering flavor and sensitive bioactives with excellent stability in various applications such as food, medicine, and cosmetics.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
