Novel Insights From Human Studies on the Role of High-Density Lipoprotein in Mortality and Noncardiovascular Disease

Dalcetrapib Reduces Risk of New-Onset Diabetes in Patients With Coronary Heart Disease

(2020) Gregory G. Schwartz et al.   DIABETES CARE

A Novel Role for CETP as Immunological Gatekeeper: Raising HDL to Cure Sepsis?

(2020) Lisanne L. Blauw et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effect of CETP inhibition with evacetrapib in patients with diabetes mellitus enrolled in the ACCELERATE trial

(2020) Venu Menon et al.   BMJ Open Diabetes Research & Care

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals

(2020) Kasper Mønsted Pedersen et al.   Journal of Hematology & Oncology

Molecular regulation of plasma lipid levels during systemic inflammation and sepsis

(2019) Mark Trinder et al.   CURRENT OPINION IN LIPIDOLOGY

Cholesteryl Ester Transfer Protein Inhibition for Preventing Cardiovascular Events

(2019) Jane Armitage et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

High-density Lipoprotein Cholesterol and All-cause and Cause-specific Mortality Among the Elderly

(2019) Zhi-Hao Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Low HDL Cholesterol and High Risk of Autoimmune Disease: Two Population-Based Cohort Studies Including 117341 Individuals

(2019) Christian M. Madsen et al.   CLINICAL CHEMISTRY

The P274S Mutation of Lecithin-Cholesterol Acyltransferase (LCAT) and Its Clinical Manifestations in a Large Kindred

(2019) Nikolaos Fountoulakis et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Very high high-density lipoprotein cholesterol is associated with increased all-cause mortality in South Koreans

(2019) In-Hwan Oh et al.   ATHEROSCLEROSIS

Causal Effects of Genetically Predicted Cardiovascular Risk Factors on Chronic Kidney Disease: A Two-Sample Mendelian Randomization Study

(2019) Hui-Min Liu et al.   Frontiers in Genetics

Repeated measures of extremely high levels of high-density lipoprotein cholesterol and subsequent all-cause mortality and cardiovascular events: A longitudinal study

(2019) Daiki Kobayashi et al.   ATHEROSCLEROSIS

2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

(2019) Francesco Cosentino et al.   EUROPEAN HEART JOURNAL

2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk

(2019) François Mach et al.   EUROPEAN HEART JOURNAL

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease

(2019) Mark Trinder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL Cholesterol, LDL Cholesterol, and Triglycerides as Risk Factors for CKD: A Mendelian Randomization Study

(2018) Matthew B. Lanktree et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Is It Time for New Thinking About High-Density Lipoprotein?

(2018) Christian M. Madsen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High-Density Lipoprotein Cholesterol and MortalityHighlights

(2018) Mark Hamer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The year in cardiology 2017: prevention

(2018) Børge G Nordestgaard et al.   EUROPEAN HEART JOURNAL

Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease

(2018) Anna Helgadottir et al.   EUROPEAN HEART JOURNAL

Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH–JAPAN study

(2018) Aya Hirata et al.   Journal of Clinical Lipidology

High density lipoprotein cholesterol and cancer: Marker or causative?

(2018) Matteo Pirro et al.   PROGRESS IN LIPID RESEARCH

A Mendelian randomization study of the effects of blood lipids on breast cancer risk

(2018) Christoph Nowak et al.   Nature Communications

Effect of Infusion of High-Density Lipoprotein Mimetic Containing Recombinant Apolipoprotein A-I Milano on Coronary Disease in Patients With an Acute Coronary Syndrome in the MILANO-PILOT Trial

(2018) Stephen J. Nicholls et al.   JAMA Cardiology

Cholesteryl Ester Transfer Protein Influences High-Density Lipoprotein Levels and Survival in Sepsis

(2018) Mark Trinder et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

High-density lipoprotein cholesterol levels, cardiovascular disease risk, and cancer: a relation which does not apply to all?

(2018) Alberico Luigi Catapano et al.   CARDIOVASCULAR RESEARCH

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis

(2018) Kelly Roveran Genga et al.   Scientific Reports

Associations between risk of overall mortality, cause-specific mortality and level of inflammatory factors with extremely low and high high-density lipoprotein cholesterol levels among American adults

(2018) Mohsen Mazidi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

HDL cholesterol concentration or HDL function: which matters?

(2017) Philip J. Barter et al.   EUROPEAN HEART JOURNAL

U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies

(2017) Christian M Madsen et al.   EUROPEAN HEART JOURNAL

Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies

(2017) Christian M. Madsen et al.   EUROPEAN HEART JOURNAL

Semiparametric methods for estimation of a nonlinear exposure-outcome relationship using instrumental variables with application to Mendelian randomization

(2017) James R. Staley et al.   GENETIC EPIDEMIOLOGY

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

(2017) Henry Rodriguez-Broadbent et al.   INTERNATIONAL JOURNAL OF CANCER

Decreased high-density lipoprotein cholesterol level is an early prognostic marker for organ dysfunction and death in patients with suspected sepsis

(2017) Mihai Cirstea et al.   JOURNAL OF CRITICAL CARE

Polygenic determinants in extremes of high-density lipoprotein cholesterol

(2017) Jacqueline S. Dron et al.   JOURNAL OF LIPID RESEARCH

High density lipoproteins and type 2 inflammatory biomarkers are negatively correlated in atopic asthmatics

(2017) Amisha V. Barochia et al.   JOURNAL OF LIPID RESEARCH

Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease

(2017) A. Michael Lincoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

A VOYAGER Meta-Analysis of the Impact of Statin Therapy on Low-Density Lipoprotein Cholesterol and Triglyceride Levels in Patients With Hypertriglyceridemia

(2016) Björn W. Karlson et al.   AMERICAN JOURNAL OF CARDIOLOGY

Lipid biomarkers and long-term risk of cancer in the Women’s Health Study

(2016) Paulette D Chandler et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update

(2016) R Agca et al.   ANNALS OF THE RHEUMATIC DISEASES

Rare Genetic Variants and High-Density Lipoprotein

(2016) Bernardo L. Trigatti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Is High-Density Lipoprotein Cholesterol Causally Related to Kidney Function?Highlights

(2016) Stefan Coassin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

High Density Lipoprotein Cholesterol and the Risk of All-Cause Mortality among U.S. Veterans

(2016) Benjamin Bowe et al.   Clinical Journal of the American Society of Nephrology

2016 European Guidelines on cardiovascular disease prevention in clinical practice

(2016) Massimo F. Piepoli et al.   EUROPEAN HEART JOURNAL

Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization

(2016) Rebecca K. Vinding et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Relationship between Very High Levels of Serum High-Density Lipoprotein Cholesterol and Cause-Specific Mortality in a 20-Year Follow-Up Study of Japanese General Population

(2016) Aya Hirata et al.   Journal of Atherosclerosis and Thrombosis

High-Density Lipoprotein Cholesterol and Cause-Specific Mortality in Individuals Without Previous Cardiovascular Conditions

(2016) Dennis T. Ko et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Low levels of high-density lipoprotein cholesterol increase the risk of incident kidney disease and its progression

(2016) Benjamin Bowe et al.   KIDNEY INTERNATIONAL

Ozanimod Induction and Maintenance Treatment for Ulcerative Colitis

(2016) William J. Sandborn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

(2016) Paolo Zanoni et al.   SCIENCE

Blood lipids and prostate cancer: a Mendelian randomization analysis

(2016) Caroline J. Bull et al.   Cancer Medicine

High-density Lipoproteins and Apolipoprotein A-I: Potential New Players in the Prevention and Treatment of Lung Disease

(2016) Elizabeth M. Gordon et al.   Frontiers in Pharmacology

Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes

(2016) Jon White et al.   JAMA Cardiology

Serum Apolipoprotein A-I and Large High-Density Lipoprotein Particles Are Positively Correlated with FEV1in Atopic Asthma

(2015) Amisha V. Barochia et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Apolipoprotein M in lipid metabolism and cardiometabolic diseases

(2015) Anna Borup et al.   CURRENT OPINION IN LIPIDOLOGY

Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes

(2015) Tove Fall et al.   DIABETES

HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study

(2015) Christiane L. Haase et al.   DIABETES

Effect of extended-release niacin on cardiovascular events and kidney function in chronic kidney disease: a post hoc analysis of the AIM-HIGH trial

(2015) Roberto S. Kalil et al.   KIDNEY INTERNATIONAL

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

(2015) G Kees Hovingh et al.   LANCET

Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials

(2015)   LANCET

HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation

(2015) Victoria A. Blaho et al.   NATURE

Causal relevance of circulating high-density lipoprotein cholesterol with cancer: a Mendelian randomization meta-analysis

(2015) Chunhua Yang et al.   Scientific Reports

Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis

(2015) Amy E. Taylor et al.   Scientific Reports

HDL in innate and adaptive immunity

(2014) A. L. Catapano et al.   CARDIOVASCULAR RESEARCH

Instrumental Variable Analysis with a Nonlinear Exposure–Outcome Relationship

(2014) Stephen Burgess et al.   EPIDEMIOLOGY

Serum lipid profile, cytokine production, and clinical outcome in patients with severe sepsis

(2014) Alexandra Lekkou et al.   JOURNAL OF CRITICAL CARE

Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117 411 patients

(2014) D. Keene et al.   BMJ-British Medical Journal

Coronary Heart Disease Risks Associated with High Levels of HDL Cholesterol

(2014) John T. Wilkins et al.   Journal of the American Heart Association

Analysis and modelling of cholesterol and high-density lipoprotein cholesterol changes across the range of C-reactive protein levels in clinical practice as an aid to better understanding of inflammation–lipid interactions

(2013) Hanna Johnsson et al.   ANNALS OF THE RHEUMATIC DISEASES

Effects of Fibrates in Kidney Disease

(2012) Min Jun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic Inhibition of CETP, Ischemic Vascular Disease and Mortality, and Possible Adverse Effects

(2012) Trine Holm Johannsen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Torcetrapib on Glucose, Insulin, and Hemoglobin A 1c in Subjects in the Investigation of Lipid Level Management to Understand its Impact in Atherosclerotic Events (ILLUMINATE) Trial

(2011) Philip J. Barter et al.   CIRCULATION

Low serum high-density lipoprotein cholesterol in childhood is associated with adolescent asthma

(2011) P. K. Yiallouros et al.   CLINICAL AND EXPERIMENTAL ALLERGY

HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

(2011) Mohamad Navab et al.   Nature Reviews Cardiology

A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis

(2010) Ludwig Kappos et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphism in the CETP Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction

(2009) Paul M. Ridker et al.   Circulation-Cardiovascular Genetics

Novel relationship of serum cholesterol with asthma and wheeze in the United States

(2009) Michael B. Fessler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Association of Loss-of-Function Mutations in the ABCA1 Gene With High-Density Lipoprotein Cholesterol Levels and Risk of Ischemic Heart Disease

(2008) Ruth Frikke-Schmidt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Variation in ABCA1 Predicts Ischemic Heart Disease in the General Population

(2007) Ruth Frikke-Schmidt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE