HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation

Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo

(2014) Mari Kono et al.   JOURNAL OF CLINICAL INVESTIGATION

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

(2013) Christopher S Garris et al.   NATURE IMMUNOLOGY

Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs

(2012) Jason G. Cyster et al.   Annual Review of Immunology

Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways

(2012) Marit Westerterp et al.   Cell Stem Cell

Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development

(2012) Bongnam Jung et al.   DEVELOPMENTAL CELL

Deficiency of Scavenger Receptor BI Leads to Impaired Lymphocyte Homeostasis and Autoimmune Disorders in Mice

(2011) Hong Feng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Engagement of S1P1-degradative mechanisms leads to vascular leak in mice

(2011) Myat Lin Oo et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis

(2011) Bianca Weinstock-Guttman et al.   Journal of Neuroinflammation

Inter-dependence of vitamin D levels with serum lipid profiles in multiple sclerosis

(2011) Bianca Weinstock-Guttman et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

(2011) C. Christoffersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics

(2010) Shobha Thangada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blood sphingolipidomics in healthy humans: impact of sample collection methodology

(2010) Samar M. Hammad et al.   JOURNAL OF LIPID RESEARCH

The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells

(2010) Guangwei Liu et al.   NATURE IMMUNOLOGY

Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice

(2010) Mara E Pitulescu et al.   Nature Protocols

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

(2010) J. Chun et al.   PHARMACOLOGICAL REVIEWS

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

(2010) J. W. Choi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

ATP-Binding Cassette Transporter G1 Negatively Regulates Thymocyte and Peripheral Lymphocyte Proliferation

(2009) Allison J. Armstrong et al.   JOURNAL OF IMMUNOLOGY

S1P1 Receptor Signaling Overrides Retention Mediated by Gαi-Coupled Receptors to Promote T Cell Egress

(2008) Trung H.M. Pham et al.   IMMUNITY

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Flow-Cytometric Phosphoprotein Analysis Reveals Agonist and Temporal Differences in Responses of Murine Hematopoietic Stem/Progenitor Cells

(2008) Demetrios Kalaitzidis et al.   PLoS One