Cefiderocol Retains Antibiofilm Activity in Multidrug-Resistant Gram-Negative Pathogens

In vivo pharmacodynamic study of cefiderocol, a novel parenteral siderophore cephalosporin, in murine thigh and lung infection models

(2019) Rio Nakamura et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MBEC Versus MBIC: the Lack of Differentiation between Biofilm Reducing and Inhibitory Effects as a Current Problem in Biofilm Methodology

(2019) Lara Thieme et al.   BIOLOGICAL PROCEDURES ONLINE

Siderophore–Antibiotic Conjugate Design: New Drugs for Bad Bugs?

(2019) Negash et al.   MOLECULES

Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria

(2019) Patrice Nordmann et al.   CLINICAL INFECTIOUS DISEASES

In Vitro Activity of Cefiderocol Against a Broad Range of Clinically Important Gram-negative Bacteria

(2019) Yoshinori Yamano   CLINICAL INFECTIOUS DISEASES

Pharmacokinetic and Pharmacodynamic Profiles of Cefiderocol, a Novel Siderophore Cephalosporin

(2019) Takayuki Katsube et al.   CLINICAL INFECTIOUS DISEASES

An overview of recent progress in siderophore-antibiotic conjugates

(2019) Huimin Kong et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

TonB-Dependent Receptor Repertoire of Pseudomonas aeruginosa for Uptake of Siderophore-Drug Conjugates

(2018) Alexandre Luscher et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship

(2018) Toshiaki Aoki et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Pharmacodynamics of cefiderocol, a novel siderophore cephalosporin, in a Pseudomonas aeruginosa neutropenic murine thigh model

(2018) Islam M. Ghazi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa

(2018) Donghoon Kang et al.   JOURNAL OF MICROBIOLOGY

The Growing Genetic and Functional Diversity of Extended Spectrum Beta-Lactamases

(2018) Sadeeq ur Rahman et al.   Biomed Research International

Enhanced Biofilm Formation by Ferrous and Ferric Iron Through Oxidative Stress in Campylobacter jejuni

(2018) Euna Oh et al.   Frontiers in Microbiology

Activity of the novel siderophore cephalosporin cefiderocol against multidrug-resistant Gram-negative pathogens

(2017) J. Dobias et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Resistance to polymyxins in Gram-negative organisms

(2017) Katy Jeannot et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Iron Acquisition Mechanisms and Their Role in the Virulence of Burkholderia Species

(2017) Aaron T. Butt et al.   Frontiers in Cellular and Infection Microbiology

Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1

(2017) Philip Hinchliffe et al.   Scientific Reports

Siderophore Cephalosporin Cefiderocol Utilizes Ferric Iron Transporter Systems for Antibacterial Activity againstPseudomonas aeruginosa

(2016) Akinobu Ito et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

(2016) Briana R. Wilson et al.   TRENDS IN MOLECULAR MEDICINE

An iron detection system determines bacterial swarming initiation and biofilm formation

(2016) Chuan-Sheng Lin et al.   Scientific Reports

Biofilms in periprosthetic orthopedic infections

(2014) Stephen J McConoughey et al.   Future Microbiology

Molecular mechanisms of antibiotic resistance

(2014) Jessica M. A. Blair et al.   NATURE REVIEWS MICROBIOLOGY

Reversibility of antibiotic resistance

(2014) Martin Sundqvist   UPSALA JOURNAL OF MEDICAL SCIENCES

Rise and dissemination of aminoglycoside resistance: the aac(6′)-Ib paradigm

(2013) María S. Ramirez et al.   Frontiers in Microbiology

Fosfomycin Enhances the Active Transport of Tobramycin in Pseudomonas aeruginosa

(2012) David L. MacLeod et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance

(2012) L. Fernandez et al.   CLINICAL MICROBIOLOGY REVIEWS

Siderophore production and biofilm formation as linked social traits

(2009) Freya Harrison et al.   ISME Journal

IscR Controls Iron-Dependent Biofilm Formation in Escherichia coli by Regulating Type I Fimbria Expression

(2008) Y. Wu et al.   JOURNAL OF BACTERIOLOGY