Platinum(iv) N-heterocyclic carbene complexes: their synthesis, characterisation and cytotoxic activity

The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

(2016) Timothy C. Johnstone et al.   CHEMICAL REVIEWS

Platinum(iv) anticancer prodrugs – hypotheses and facts

(2016) Dan Gibson   DALTON TRANSACTIONS

Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group

(2015) Julienne K. Muenzner et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pyridyl- and diphenylphosphinoethyl-functionalised N-heterocyclic carbene platinum methyl complexes

(2015) Nikolaos Tsoureas et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Synthesis, structural characterization and in vitro anti-cancer activity of functionalized N-heterocyclic carbene platinum and palladium complexes

(2015) Georges Dahm et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Characterization of the mechanism of reduction of trans-diamminetetrachloroplatinum(IV) by l-cysteine and dl-homocysteine

(2015) Taotao Lu et al.   TRANSITION METAL CHEMISTRY

Say No to DMSO: Dimethylsulfoxide Inactivates Cisplatin, Carboplatin, and Other Platinum Complexes

(2014) M. D. Hall et al.   CANCER RESEARCH

Chemistry of Iron N-Heterocyclic Carbene Complexes: Syntheses, Structures, Reactivities, and Catalytic Applications

(2014) Korbinian Riener et al.   CHEMICAL REVIEWS

Group 1 and 2 and Early Transition Metal Complexes Bearing N-Heterocyclic Carbene Ligands: Coordination Chemistry, Reactivity, and Applications

(2014) Stéphane Bellemin-Laponnaz et al.   CHEMICAL REVIEWS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Group 10 Metal Complexes with Chelating Macrocyclic Dicarbene Ligands Bearing a 2,6-Lutidinyl Bridge: Synthesis, Reactivity, and Catalytic Activity

(2014) Andrea Biffis et al.   ORGANOMETALLICS

Metal/N-Heterocyclic Carbene Complexes: Opportunities for the Development of Anticancer Metallodrugs

(2013) Federico Cisnetti et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Luminescent organoplatinum(ii) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity

(2013) Taotao Zou et al.   CHEMICAL COMMUNICATIONS

Oxidation of anticancer Pt(ii) complexes with monodentate phosphane ligands: towards stable but active Pt(iv) prodrugs

(2013) María Ángeles Medrano et al.   CHEMICAL COMMUNICATIONS

Exploring Nitrogen Ligand Diversity intrans-N-Heterocyclic Carbene-Amine Platinum Complexes : Synthesis, Characterization, and Application to Fluorescence

(2013) Edith Chardon et al.   Chemistry-An Asian Journal

Antitumor trans-N-Heterocyclic Carbene–Amine–Pt(II) Complexes: Synthesis of Dinuclear Species and Exploratory Investigations of DNA Binding and Cytotoxicity Mechanisms

(2013) Mélanie Chtchigrovsky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs

(2012) Wukun Liu et al.   CHEMICAL SOCIETY REVIEWS

The potential of organometallic complexes in medicinal chemistry

(2012) Gilles Gasser et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Platinum(ii) and platinum(iv) complexes stabilized by abnormal/mesoionic C4-bound dicarbenes

(2012) Vsevolod Khlebnikov et al.   DALTON TRANSACTIONS

Derivatization of Preformed Platinum N-Heterocyclic Carbene Complexes with Amino Acid and Peptide Ligands and Cytotoxic Activities toward Human Cancer Cells

(2012) Edith Chardon et al.   ORGANOMETALLICS

Easy Derivatisation of Group 10 N-Heterocyclic Carbene Complexes and In Vitro Evaluation of an Anticancer Oestradiol Conjugate

(2012) Edith Chardon et al.   ChemPlusChem

Direct functionalisation of group 10 N-heterocyclic carbene complexes for diversity enhancement

(2011) Edith Chardon et al.   CHEMICAL COMMUNICATIONS

Synthetic Routes to N-Heterocyclic Carbene Precursors

(2011) Laure Benhamou et al.   CHEMICAL REVIEWS

Anticancer Platinum (IV) Prodrugs with Novel Modes of Activity

(2011) Chee Fei Chin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Reactive oxygen species participate in the p38-mediated apoptosis induced by potassium deprivation and staurosporine in cerebellar granule neurons

(2011) Yazmín Ramiro-Cortés et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Advances in metal–carbene complexes as potent anti-cancer agents

(2011) Arnaud Gautier et al.   Metallomics

One-step synthesis of composite vesicles: Direct polymerization and in situ over-oxidation of thiophene

(2011) Hang Sun et al.   Chemical Science

Beyond catalysis: N-heterocyclic carbene complexes as components for medicinal, luminescent, and functional materials applications

(2010) Laszlo Mercs et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs

(2010) Myriem Skander et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Platinum(IV) Complexes with Chelating N-Heterocyclic Carbene Ligands

(2010) Dirk Meyer et al.   ORGANOMETALLICS

The Medicinal Applications of Imidazolium Carbene−Metal Complexes

(2009) Khadijah M. Hindi et al.   CHEMICAL REVIEWS

N-Heterocyclic Carbenes in Late Transition Metal Catalysis

(2009) Silvia Díez-González et al.   CHEMICAL REVIEWS

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mitochondria-Targeted Chemotherapeutics: The Rational Design of Gold(I)N-Heterocyclic Carbene Complexes That Are Selectively Toxic to Cancer Cells and Target Protein Selenols in Preference to Thiols

(2008) James L. Hickey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY