Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties

Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection

(2018) Shang Ma et al.   CELL

PIEZO1 Channel Is a Potential Regulator of Synovial Sarcoma Cell-Viability

(2018) Takahisa Suzuki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Continuous hypergravity alters the cytoplasmic elasticity of MC3T3-E1 osteoblasts via actin filaments

(2018) Shuai Zhou et al.   JOURNAL OF BIOMECHANICS

PIEZO1 functions as a potential oncogene by promoting cell proliferation and migration in gastric carcinogenesis

(2018) Jinglin Zhang et al.   MOLECULAR CARCINOGENESIS

Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

(2018) Li He et al.   NATURE

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

(2018) Carlos Pardo-Pastor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

(2018) Xin Chen et al.   NEURON

Invadosomes are coming: new insights into function and disease relevance

(2017) Elyse K. Paterson et al.   FEBS Journal

Mechanical stretch triggers rapid epithelial cell division through Piezo1

(2017) S. A. Gudipaty et al.   NATURE

Mechanoreciprocity in cell migration

(2017) Sjoerd van Helvert et al.   NATURE CELL BIOLOGY

Matrix Metalloproteinases: A challenging paradigm of cancer management

(2017) Ali Alaseem et al.   SEMINARS IN CANCER BIOLOGY

How cells channel their stress: Interplay between Piezo1 and the cytoskeleton

(2017) Jamison L. Nourse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Touch, Tension, and Transduction – The Function and Regulation of Piezo Ion Channels

(2017) Jason Wu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

(2016) ShengPeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways

(2016) Wei-Chien Hung et al.   Cell Reports

Migration in Confined 3D Environments Is Determined by a Combination of Adhesiveness, Nuclear Volume, Contractility, and Cell Stiffness

(2015) Lena A. Lautscham et al.   BIOPHYSICAL JOURNAL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

(2015) Chouyang Li et al.   Scientific Reports

Cellular traction stresses mediate extracellular matrix degradation by invadopodia

(2014) Rachel J. Jerrell et al.   Acta Biomaterialia

STIM1- and Orai1-mediated Ca2+oscillation orchestrates invadopodium formation and melanoma invasion

(2014) Jianwei Sun et al.   JOURNAL OF CELL BIOLOGY

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Physical Biology in Cancer. 4. Physical cues guide tumor cell adhesion and migration

(2013) Kimberly M. Stroka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration

(2012) Brian J. McHugh et al.   PLoS One

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential

(2010) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

(2009) B. J. McHugh et al.   JOURNAL OF CELL SCIENCE

Physical forces during collective cell migration

(2009) Xavier Trepat et al.   Nature Physics

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High Resolution Traction Force Microscopy Based on Experimental and Computational Advances

(2007) Benedikt Sabass et al.   BIOPHYSICAL JOURNAL