Validating a Numerical Simulation of the ConsiGma(R) Coater

A Thermodynamic Balance Model for Liquid Film Drying Kinetics of a Tablet Film Coating and Drying Process

(2019) Bumjoon Cha et al.   AAPS PHARMSCITECH

Industrial scale simulations of tablet coating using GPU based DEM: A validation study

(2019) Hermann Kureck et al.   CHEMICAL ENGINEERING SCIENCE

Shedding light on coatings: Real-time monitoring of coating quality at industrial scale

(2019) Stephan Sacher et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Extended validation and verification of XPS/AVL-Fire™, a computational CFD-DEM software platform

(2019) T. Forgber et al.   POWDER TECHNOLOGY

A quantitative comparison of in-line coating thickness distributions obtained from a pharmaceutical tablet mixing process using discrete element method and terahertz pulsed imaging

(2018) Chunlei Pei et al.   CHEMICAL ENGINEERING SCIENCE

Modeling, experimental trials, and design space determination for the GEA ConsiGma™ coater

(2018) Ian C. Kemp et al.   DRYING TECHNOLOGY

Control of three different continuous pharmaceutical manufacturing processes: Use of soft sensors

(2018) Jakob Rehrl et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Detailed Modeling and Process Design of an Advanced Continuous Powder Mixer

(2018) Peter Toson et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In-depth Evaluation of Data Collected During a Continuous Pharmaceutical Manufacturing Process: A Multivariate Statistical Process Monitoring Approach

(2018) Ana F. Silva et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Computational Fluid Dynamics-Discrete Element Method Modeling of an Industrial-Scale Wurster Coater

(2018) Peter Böhling et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Impulse-based dynamics for studying quasi-static granular flows: Application to hopper emptying of non-spherical particles

(2017) Peter Toson et al.   POWDER TECHNOLOGY

Simulating wet gas–solid fluidized beds using coarse-grid CFD-DEM

(2016) M. Girardi et al.   CHEMICAL ENGINEERING SCIENCE

Simulation of a tablet coating process at different scales using DEM

(2016) P. Boehling et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Analysis of large-scale tablet coating: Modeling, simulation and experiments

(2016) P. Boehling et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Evaluation of the tablets’ surface flow velocities in pan coaters

(2016) Rok Dreu et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Numerical study on a heat transfer model in a Lagrangian fluid dynamics simulation

(2016) Kazuya Takabatake et al.   INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER

Setting the process parameters for the coating process in order to assure tablet appearance based on multivariate analysis of prior data

(2016) Shuichi Tanabe et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

DEM–compartment–population balance model for particle coating in a horizontal rotating drum

(2015) Rahul Kumar et al.   CHEMICAL ENGINEERING SCIENCE

Comparisons of intra-tablet coating variability using DEM simulations, asymptotic limit models, and experiments

(2015) Ben Freireich et al.   CHEMICAL ENGINEERING SCIENCE

Modeling of an Active Tablet Coating Process

(2015) Gregor Toschkoff et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Residence time distributions of different size particles in the spray zone of a Wurster fluid bed studied using DEM-CFD

(2015) Liang Li et al.   POWDER TECHNOLOGY

Measurement of drag coefficients of non-spherical particles with a camera-based method

(2015) B. Krueger et al.   POWDER TECHNOLOGY

Optical coherence tomography as a novel tool for in-line monitoring of a pharmaceutical film-coating process

(2014) Daniel Markl et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Angular Circulation Speed of Tablets in a Vibratory Tablet Coating Pan

(2013) Rahul Kumar et al.   AAPS PHARMSCITECH

Large-scale CFD–DEM simulations of fluidized granular systems

(2013) Dalibor Jajcevic et al.   CHEMICAL ENGINEERING SCIENCE

Distribution nucleation: Quantifying liquid distribution on the particle surface using the dimensionless particle coating number

(2013) Waithira I.J. Kariuki et al.   CHEMICAL ENGINEERING SCIENCE

Spray models for discrete element simulations of particle coating processes

(2013) Gregor Toschkoff et al.   CHEMICAL ENGINEERING SCIENCE

Lattice-Boltzmann simulation of fluid flow through packed beds of uniform spheres: Effect of porosity

(2013) L.W. Rong et al.   CHEMICAL ENGINEERING SCIENCE

Optimization of the inter-tablet coating uniformity for an active coating process at lab and pilot scale

(2013) Sarah Just et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Modeling and Coupling Particle Scale Heat Transfer with DEM through Heat Transfer Mechanisms

(2013) Chang-sheng Bu et al.   NUMERICAL HEAT TRANSFER PART A-APPLICATIONS

DEM simulation of continuous tablet coating: Effects of tablet shape and fill level on inter-tablet coating variability

(2011) Daniele Suzzi et al.   CHEMICAL ENGINEERING SCIENCE

Numerical analysis of the dynamics of two- and three-dimensional fluidized bed reactors using an Euler–Lagrange approach

(2011) Perrine Pepiot et al.   POWDER TECHNOLOGY

Optimization of Process Parameters for a Quasi-Continuous Tablet Coating System Using Design of Experiments

(2010) Christine Cahyadi et al.   AAPS PHARMSCITECH

A semi-empirical model for the drag force and fluid–particle interaction in polydisperse suspensions

(2010) Fernando Cello et al.   CHEMICAL ENGINEERING SCIENCE

Large-scale powder mixer simulations using massively parallel GPUarchitectures

(2010) Charles A. Radeke et al.   CHEMICAL ENGINEERING SCIENCE

Inter-tablet coating variability: Tablet residence time variability

(2009) Arjun Kalbag et al.   CHEMICAL ENGINEERING SCIENCE

Imaging pharmaceutical tablets with optical coherence tomography

(2009) Jakob M.A. Mauritz et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

New simple correlation formula for the drag coefficient of non-spherical particles

(2007) Andreas Hölzer et al.   POWDER TECHNOLOGY