PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking

Cooperativity of E-prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle

(2019) James V. Michael et al.   FASEB JOURNAL

Distinctive Effects of GM-CSF and M-CSF on Proliferation and Polarization of Two Major Pulmonary Macrophage Populations

(2019) Christina Draijer et al.   JOURNAL OF IMMUNOLOGY

Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation: Mechanistic Implications for Desquamative Interstitial Pneumonitis

(2019) Takuji Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Vitamin D3-vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function

(2019) Guangan Hu et al.   EBioMedicine

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self‐renewal and identity

(2019) René Rauschmeier et al.   EMBO JOURNAL

Prostaglandin E 2 suppresses human group 2 innate lymphoid cell function

(2018) Jovana Maric et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria

(2017) Zhigang Li et al.   JOURNAL OF IMMUNOLOGY

Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice

(2017) Christine K. Wong et al.   JOURNAL OF IMMUNOLOGY

SmokeHaz

(2016) Leah Jayes et al.   CHEST

Innate immune responses in the ageing lung

(2016) D. M. Boe et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages

(2016) Wenhai Deng et al.   JOURNAL OF IMMUNOLOGY

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

(2014) M. Rosas et al.   SCIENCE

Age-Associated Changes in Immune Function: Impact of Vitamin E Intervention and the Underlying Mechanisms

(2014) Dayong Wu et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Role of CC Chemokine Receptor 4 in Natural Killer Cell Activation during Acute Cigarette Smoke Exposure

(2013) Valerie R. Stolberg et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions

(2013) Katsuhide Okunishi et al.   FASEB JOURNAL

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of Recently Migrated Monocytes in Cigarette Smoke-Induced Lung Inflammation in Different Strain of Mice

(2013) Sandra Pérez-Rial et al.   PLoS One

Reduced Number and Morphofunctional Change of Alveolar Macrophages in MafB Gene-Targeted Mice

(2013) Michiko Sato-Nishiwaki et al.   PLoS One

Regulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2

(2012) Emilie Bourdonnay et al.   JOURNAL OF LEUKOCYTE BIOLOGY

E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae

(2012) David M. Aronoff et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Hazardous Compounds in Tobacco Smoke

(2011) Reinskje Talhout et al.   International Journal of Environmental Research and Public Health

Ageing is associated with diminished apoptotic cell clearance in vivo

(2010) T. Aprahamian et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cigarette smoke modulates PGE2 and host defence against Moraxella catarrhalis infection in human airway epithelial cells

(2010) WEIYUN ZHANG et al.   RESPIROLOGY

Cigarette Smoke Exposure Impairs Pulmonary Bacterial Clearance and Alveolar Macrophage Complement-Mediated Phagocytosis of Streptococcus pneumoniae

(2009) J. C. Phipps et al.   INFECTION AND IMMUNITY

Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling

(2009) Alexandra I. Medeiros et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epac and PKA: a tale of two intracellular cAMP receptors

(2008) Xiaodong Cheng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA