Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer

Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol

(2020) Yasuharu Yazawa et al.   Journal of Natural Medicines

Free radical scavenging activity of the peptide from the Alcalase hydrolysate of the edible aquacultural seahorse ( Hippocampus abdominalis )

(2019) Hyun‐Soo Kim et al.   JOURNAL OF FOOD BIOCHEMISTRY

2′-Hydroxy-5′-methoxyacetophenone attenuates the inflammatory response in LPS-induced BV-2 and RAW264.7 cells via NF-κB signaling pathway

(2019) YuanYuan Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Epithelial Mesenchymal Transition in Tumor Metastasis

(2018) Vivek Mittal   Annual Review of Pathology-Mechanisms of Disease

Significantly Accelerated Osteoblast Cell Growth on TiO2/SrHA Composite Mediated by Phenolic Compounds (BHM) from Hippocampus kuda Bleeler

(2018) Qiong Yuan et al.   ACS Applied Materials & Interfaces

Protective effect of enzymatic hydrolysates from seahorse (Hippocampus abdominalis) against H2O2-mediated human umbilical vein endothelial cell injury

(2018) Yunok Oh et al.   BIOMEDICINE & PHARMACOTHERAPY

Elevation of androgen receptor promotes prostate cancer metastasis by induction of epithelial-mesenchymal transition and reduction of KAT5

(2018) Ching-Yu Lin et al.   CANCER SCIENCE

1-(5-Bromo-2-hydroxy-4-methoxyphenyl)ethanone [SE1] Inhibits MMP-9 Expression by Regulating NF-κB and MAPKs Signaling Pathways in HT1080 Human Fibrosarcoma Cells

(2018) Fang Gong et al.   Evidence-based Complementary and Alternative Medicine

Activation of phosphatidylinositol 3-kinase/AKT/snail signaling pathway contributes to epithelial-mesenchymal transition-induced multi-drug resistance to sorafenib in hepatocellular carcinoma cells

(2017) Jiejie Dong et al.   PLoS One

Effect of Three-spot Seahorse Petroleum Ether Extract on Lipopolysaccharide Induced Macrophage RAW264.7 Inflammatory Cytokine Nitric Oxide and Composition Analysis

(2015) LiPing Chen et al.   Journal of Oleo Science

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

(2015) Mark A. Feitelson et al.   SEMINARS IN CANCER BIOLOGY

A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition

(2015) Wenting Xu et al.   Cell Adhesion & Migration

Seahorse-derived peptide suppresses invasive migration of HT1080 fibrosarcoma cells by competing with intracellular α-enolase for plasminogen binding and inhibiting uPA-mediated activation of plasminogen

(2015) Yong-Tae Kim et al.   BMB Reports

Protective effects of seahorse extracts in a rat castration and testosterone-induced benign prostatic hyperplasia model and mouse oligospermatism model

(2014) Dong-Hui Xu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Molecular alterations and emerging targets in castration resistant prostate cancer

(2014) D. Lorente et al.   EUROPEAN JOURNAL OF CANCER

3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions

(2014) Carsten Wenzel et al.   EXPERIMENTAL CELL RESEARCH

Targeting the PI3K/Akt/mTOR pathway in castration-resistant prostate cancer

(2013) Rhonda L Bitting et al.   ENDOCRINE-RELATED CANCER

Synergistic Targeting of PI3K/AKT Pathway and Androgen Receptor Axis Significantly Delays Castration-Resistant Prostate Cancer ProgressionIn Vivo

(2013) Christian Thomas et al.   MOLECULAR CANCER THERAPEUTICS

Identification, synthesis and characterization of a novel antimicrobial peptide HKPLP derived from Hippocampus kuda Bleeker

(2012) Dandan Sun et al.   JOURNAL OF ANTIBIOTICS

Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways

(2012) S.W.A. Himaya et al.   TOXICOLOGY IN VITRO

Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth

(2011) David J. Mulholland et al.   CANCER CELL

Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer

(2011) Brett S. Carver et al.   CANCER CELL

Androgen receptor levels are upregulated by Akt in prostate cancer

(2011) S. Ha et al.   ENDOCRINE-RELATED CANCER

Alternatively spliced androgen receptor variants

(2011) Scott M Dehm et al.   ENDOCRINE-RELATED CANCER

1-(5-bromo-2-hydroxy-4-methoxyphenyl)ethanone [SE1] suppresses pro-inflammatory responses by blocking NF-κB and MAPK signaling pathways in activated microglia

(2011) S.W.A. Himaya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PC3 is a cell line characteristic of prostatic small cell carcinoma

(2011) Sheng Tai et al.   PROSTATE

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Effect of rapeseed oil-derived plant sterol and stanol esters on atherosclerosis parameters in cholesterol-challenged heterozygous Watanabe Heritable Hyperlipidaemic rabbits

(2009) Malene Schrøder et al.   BRITISH JOURNAL OF NUTRITION

Purification of a peptide from seahorse, that inhibits TPA-induced MMP, iNOS and COX-2 expression through MAPK and NF-κB activation, and induces human osteoblastic and chondrocytic differentiation

(2009) BoMi Ryu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Tocopherol, tocotrienol and plant sterol contents of vegetable oils and industrial fats

(2007) Heidi Schwartz et al.   JOURNAL OF FOOD COMPOSITION AND ANALYSIS