An Optimized Dual Extraction Method for the Simultaneous and Accurate Analysis of Polar Metabolites and Lipids Carried out on Single Biological Samples

Global Metabolomic and Lipidomic Analysis Reveal the Synergistic Effect of Bufalin in Combination with Cinobufagin against HepG2 Cells

(2020) Jinghui Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Simultaneous Measurement of Metabolite Concentration and Isotope Incorporation by Mass Spectrometry

(2020) Maud Heuillet et al.   ANALYTICAL CHEMISTRY

The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds

(2020) Juliette Legler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Important Considerations for Sample Collection in Metabolomics Studies with a Special Focus on Applications to Liver Functions

(2020) Lorraine Smith et al.   Metabolites

Systems metabolomics: from metabolomic snapshots to design principles

(2020) Chiara Damiani et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolomic-based assessment reveals dysregulation of lipid profiles in human liver cells exposed to environmental obesogens

(2020) Marco E. Franco et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Validated comprehensive metabolomics and lipidomics analysis of colon tissue and cell lines

(2019) Caroline Rombouts et al.   ANALYTICA CHIMICA ACTA

Fenofibrate‐induced hepatotoxicity: A case with a special feature that is different from those in the LiverTox database

(2019) Shizhan Ma et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

The Power of LC-MS Based Multiomics: Exploring Adipogenic Differentiation of Human Mesenchymal Stem/Stromal Cells

(2019) Evelyn Rampler et al.   MOLECULES

Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig

(2019) Nathalie Poupin et al.   Scientific Reports

Metabolic and lipidomic characterization of malignant pleural effusion in human lung cancer

(2019) Zhiyi Yang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Methodology for the Validation of Isotopic Analyses by Mass Spectrometry in Stable-Isotope Labeling Experiments

(2018) Maud Heuillet et al.   ANALYTICAL CHEMISTRY

Improving metabolome coverage and data quality: advancing metabolomics and lipidomics for biomarker discovery

(2018) Dajana Vuckovic   CHEMICAL COMMUNICATIONS

Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD?

(2018) M. Croyal et al.   DIABETES & METABOLISM

New plasma preparation approach to enrich metabolome coverage in untargeted metabolomics: plasma protein bound hydrophobic metabolite release with proteinase K

(2018) Renata Wawrzyniak et al.   Scientific Reports

Metabolomic and lipidomic profile in men with obstructive sleep apnoea: implications for diagnosis and biomarkers of cardiovascular risk

(2018) Adriana Lebkuchen et al.   Scientific Reports

An Untargeted Metabolomics Approach to Investigate the Metabolic Modulations of HepG2 Cells Exposed to Low Doses of Bisphenol A and 17β-Estradiol

(2018) Nicolas J. Cabaton et al.   Frontiers in Endocrinology

Development, characterization and comparisons of targeted and non-targeted metabolomics methods

(2018) Anton Ribbenstedt et al.   PLoS One

Metabolism disrupting chemicals and metabolic disorders

(2017) Jerrold J. Heindel et al.   REPRODUCTIVE TOXICOLOGY

Metabolomics for Plant Improvement: Status and Prospects

(2017) Rakesh Kumar et al.   Frontiers in Plant Science

Integration of metabolomics, lipidomics and clinical data using a machine learning method

(2016) Animesh Acharjee et al.   BMC BIOINFORMATICS

Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology

(2016) Cristina Coman et al.   MOLECULAR & CELLULAR PROTEOMICS

MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

(2016) Ernesto S. Nakayasu et al.   mSystems

Metabolite profiling in plasma and tissues of ob/ob and db/db mice identifies novel markers of obesity and type 2 diabetes

(2015) Pieter Giesbertz et al.   DIABETOLOGIA

A novel approach to the simultaneous extraction and non-targeted analysis of the small molecules metabolome and lipidome using 96-well solid phase extraction plates with column-switching technology

(2015) Yubo Li et al.   JOURNAL OF CHROMATOGRAPHY A

Sampling of intracellular metabolites for stationary and non-stationary 13C metabolic flux analysis in Escherichia coli

(2014) Pierre Millard et al.   ANALYTICAL BIOCHEMISTRY

Comparison of Pharmacokinetics of Two Fenofibrate Tablet Formulations in Healthy Human Subjects

(2014) Siddharth S. Chachad et al.   CLINICAL THERAPEUTICS

Fast sampling method for mammalian cell metabolic analyses using liquid chromatography–mass spectrometry

(2014) Giuseppe Martano et al.   Nature Protocols

Peroxisome Proliferator-Activated Receptor α Activation Induces Hepatic Steatosis, Suggesting an Adverse Effect

(2014) Fang Yan et al.   PLoS One

PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells

(2014) Alexandra Rogue et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metabolomics in toxicology and preclinical research

(2014) Tzutzuy Ramirez   ALTEX-Alternatives to Animal Experimentation

Mammalian cell metabolomics: Experimental design and sample preparation

(2013) Zacarías León et al.   ELECTROPHORESIS

In-vial dual extraction liquid chromatography coupled to mass spectrometry applied to streptozotocin-treated diabetic rats. Tips and pitfalls of the method

(2013) Joanna Godzien et al.   JOURNAL OF CHROMATOGRAPHY A

Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry

(2013) Shili Chen et al.   JOURNAL OF CHROMATOGRAPHY A

In-Vial Dual Extraction for Direct LC-MS Analysis of Plasma for Comprehensive and Highly Reproducible Metabolic Fingerprinting.

(2012) Luke Whiley et al.   ANALYTICAL CHEMISTRY

Metabolomics: the apogee of the omics trilogy

(2012) Gary J. Patti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cancer detection and biopsy classification using concurrent histopathological and metabolomic analysis of core biopsies

(2012) Meredith V Brown et al.   Genome Medicine

Metabolomics: the final frontier?

(2012) Timothy D Veenstra   Genome Medicine

Multi-platform characterization of the human cerebrospinal fluid metabolome: a comprehensive and quantitative update

(2012) Rupasri Mandal et al.   Genome Medicine

The Emerging Field of Quantitative Blood Metabolomics for Biomarker Discovery in Critical Illnesses

(2011) Natalie J. Serkova et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

(2011) Athanasia D Panopoulos et al.   CELL RESEARCH

Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling

(2011) Christopher A Sellick et al.   Nature Protocols

Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice

(2011) Yingchang Lu et al.   PHYSIOLOGICAL GENOMICS

Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice

(2009) Maaike H. Oosterveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extraction of organic compounds with room temperature ionic liquids

(2009) Colin F. Poole et al.   JOURNAL OF CHROMATOGRAPHY A

Untargeted Metabolomic Profiling as an Evaluative Tool of Fenofibrate-Induced Toxicology in Fischer 344 Male Rats

(2009) Tetsuya Ohta et al.   TOXICOLOGIC PATHOLOGY

Metabolomics-based methods for early disease diagnostics

(2008) GA Nagana Gowda et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach

(2008) Bryson D Bennett et al.   Nature Protocols