Sex and SP-A2 Dependent NAD(H) Redox Alterations in Mouse Alveolar Macrophages in Response to Ozone Exposure: Potential Implications for COVID-19

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

(2020) Livan Delgado-Roche et al.   ARCHIVES OF MEDICAL RESEARCH

Potential Cytoprotective Activity of Ozone Therapy in SARS-CoV-2/COVID-19

(2020) Gregorio Martínez-Sánchez et al.   Antioxidants

Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

(2020) Jian-Min Jin et al.   Frontiers in Public Health

Sex-Specific Regulation of Gene Expression Networks by Surfactant Protein A (SP-A) Variants in Alveolar Macrophages in Response to Klebsiella pneumoniae

(2020) Nithyananda Thorenoor et al.   Frontiers in Immunology

The Importance of Redox Status in the Frame of Lifestyle Approaches and the Genetics of the Lung Innate Immune Molecules, SP-A1 and SP-A2, on Differential Outcomes of COVID-19 Infection

(2020) Fotios Tekos et al.   Antioxidants

Optical Redox Imaging Detects the Effects of DEK Oncogene Knockdown on the Redox State of MDA-MB-231 Breast Cancer Cells

(2019) Yu Wen et al.   MOLECULAR IMAGING AND BIOLOGY

The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

(2019) Rosaria Di Mauro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome

(2019) George T. Noutsios et al.   Frontiers in Immunology

The Metabolic Signature of Macrophage Responses

(2019) Antonella Viola et al.   Frontiers in Immunology

Differential Impact of Co-expressed SP-A1/SP-A2 Protein on AM miRNome; Sex Differences

(2019) Nithyananda Thorenoor et al.   Frontiers in Immunology

Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma

(2019) Ye Yuan et al.   Stem Cell Research & Therapy

Monocyte-derived Alveolar Macrophages: The Dark Side of Lung Repair?

(2018) Alexandra C. McQuattie-Pimentel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Deletion of c-FLIP from CD11bhi Macrophages Prevents Development of Bleomycin-induced Lung Fibrosis

(2018) Alexandra L. McCubbrey et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD

(2018) Olivia I. Kolenc et al.   ANTIOXIDANTS & REDOX SIGNALING

Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism

(2018) Russell P. Goodman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro-inflammatory, pro-repair, angiogenic activation pattern, likely associated with macrophage iron accumulation

(2018) Jungnam Lee et al.   PLoS One

Changes in Metabolites Present in Lung-Lining Fluid Following Exposure of Humans to Ozone

(2018) WanYun Cheng et al.   TOXICOLOGICAL SCIENCES

Optical Redox Imaging of Lonidamine Treatment Response of Melanoma Cells and Xenografts

(2018) He N. Xu et al.   MOLECULAR IMAGING AND BIOLOGY

Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice

(2018) Ignacio Celestino et al.   Frontiers in Immunology

Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Klebsiella pneumoniae Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival

(2018) Nithyananda Thorenoor et al.   Frontiers in Immunology

Gender-dependent differences of mitochondrial function and oxidative stress in rat skeletal muscle at rest and after exercise training

(2017) Firas Farhat et al.   REDOX REPORT

Fluorescence quenching of free and bound NADH in HeLa cells determined by hyperspectral imaging and unmixing of cell autofluorescence

(2017) Aziz Ul Rehman et al.   Biomedical Optics Express

SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved

(2017) George T. Noutsios et al.   Biology of Sex Differences

Metabolism Supports Macrophage Activation

(2017) P. Kent Langston et al.   Frontiers in Immunology

Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy

(2016) Alba Alfonso-García et al.   JOURNAL OF BIOMEDICAL OPTICS

Correlating two-photon excited fluorescence imaging of breast cancer cellular redox state with seahorse flux analysis of normalized cellular oxygen consumption

(2016) Jue Hou et al.   JOURNAL OF BIOMEDICAL OPTICS

Regulation of ozone-induced lung inflammation and injury by the β-galactoside-binding lectin galectin-3

(2015) Vasanthi R. Sunil et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues

(2014) A. Varone et al.   CANCER RESEARCH

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome

(2014) David S. Phelps et al.   Journal of Proteomics

Effect of ozone exposure and infection on bronchoalveolar lavage: Sex differences in response patterns

(2014) Anatoly N. Mikerov et al.   TOXICOLOGY LETTERS

Optical Metabolic Imaging Identifies Glycolytic Levels, Subtypes, and Early-Treatment Response in Breast Cancer

(2013) A. J. Walsh et al.   CANCER RESEARCH

M1 and M2 Macrophages: Oracles of Health and Disease

(2013) Charles Mills   CRITICAL REVIEWS IN IMMUNOLOGY

Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation

(2013) Kyle P. Quinn et al.   Scientific Reports

REDOX IMAGING OF THE p53-DEPENDENT MITOCHONDRIAL REDOX STATE IN COLON CANCER EX VIVO

(2013) HE N. XU et al.   Journal of Innovative Optical Health Sciences

Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity

(2013) He N. Xu et al.   Journal of Innovative Optical Health Sciences

Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lungKlebsiella Pneumoniaeinfection

(2012) Faryal Durrani et al.   EXPERIMENTAL LUNG RESEARCH

Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (−/−) mice

(2012) Anatoly N. Mikerov et al.   MICROBIAL PATHOGENESIS

Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A

(2012) David S Phelps et al.   Proteome Science

Classical and alternative macrophage activation in the lung following ozone-induced oxidative stress

(2012) Vasanthi R. Sunil et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alternatively Activated Macrophages and Airway Disease

(2011) Derek E. Byers et al.   CHEST

Bronchoalveolar lavage cell pattern from healthy human lung

(2011) M. Heron et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement

(2011) David S Phelps et al.   Proteome Science

Redox-optimized ROS balance: A unifying hypothesis

(2010) M.A. Aon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies

(2010) Ahmed A Heikal   Biomarkers in Medicine

Optical Redox Ratio Differentiates Breast Cancer Cell Lines Based on Estrogen Receptor Status

(2010) Julie Hanson Ostrander et al.   CANCER RESEARCH

HumanizedSFTPA1andSFTPA2Transgenic Mice Reveal Functional Divergence of SP-A1 and SP-A2

(2010) Guirong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exacerbated Innate Host Response to SARS-CoV in Aged Non-Human Primates

(2010) Saskia L. Smits et al.   PLoS Pathogens

Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis

(2009) Gin C. Chuang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

(2009) Rizwanul Haque et al.   Proteome Science

Macrophages in the embryo and beyond: Much more than just giant phagocytes

(2008) Dmitry A. Ovchinnikov   GENESIS

Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants

(2007) Anatoly N. Mikerov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING