Synergy Screening Identifies a Compound That Selectively Enhances the Antibacterial Activity of Nitric Oxide

Recent Advances in Anti-virulence Therapeutic Strategies With a Focus on Dismantling Bacterial Membrane Microdomains, Toxin Neutralization, Quorum-Sensing Interference and Biofilm Inhibition

(2019) Osmel Fleitas Martínez et al.   Frontiers in Cellular and Infection Microbiology

Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies

(2018) David Izuchukwu Ugwu et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

FDA Approval Summary: Dabrafenib and Trametinib for the Treatment of Metastatic Non‐Small Cell Lung Cancers HarboringBRAF V600EMutations

(2018) Lauretta Odogwu et al.   ONCOLOGIST

The Antimicrobial Activity of a Carbon Monoxide Releasing Molecule (EBOR-CORM-1) Is Shaped by Intraspecific Variation within Pseudomonas aeruginosa Populations

(2018) Lindsey Flanagan et al.   Frontiers in Microbiology

Riluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer’s disease

(2018) Masahir Okamoto et al.   Translational Psychiatry

Loss of DksA leads to multi-faceted impairment of nitric oxide detoxification by Escherichia coli

(2018) Wen Kang Chou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistance

(2017) Seth W. Dickey et al.   NATURE REVIEWS DRUG DISCOVERY

Antibiotic resistance

(2017) Marianne Frieri et al.   Journal of Infection and Public Health

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

(2016) Michaël Cerezo et al.   CANCER CELL

Discovery and dissection of metabolic oscillations in the microaerobic nitric oxide response network ofEscherichia coli

(2016) Jonathan L. Robinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

A biochemical engineering view of the quest for immune-potentiating anti-infectives

(2016) Wen Kang Chou et al.   Current Opinion in Chemical Engineering

CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli

(2015) Jayne Louise Wilson et al.   ANTIOXIDANTS & REDOX SIGNALING

Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box

(2015) Pedro Martins et al.   MOLECULES

Selective small-molecule inhibition of an RNA structural element

(2015) John A. Howe et al.   NATURE

A Kinetic Platform to Determine the Fate of Hydrogen Peroxide in Escherichia coli

(2015) Kristin J. Adolfsen et al.   PLoS Computational Biology

Finding alternatives to antibiotics

(2014) Heather K. Allen et al.   Annals of the New York Academy of Sciences

Deciphering nitric oxide stress in bacteria with quantitative modeling

(2014) Jonathan L Robinson et al.   CURRENT OPINION IN MICROBIOLOGY

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

(2014) Lesley A. Mathews Griner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dabrafenib: First Global Approval

(2013) Anita D. Ballantyne et al.   DRUGS

Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens

(2013) Daniel E. Kadouri et al.   PLoS One

A Kinetic Platform to Determine the Fate of Nitric Oxide in Escherichia coli

(2013) Jonathan L. Robinson et al.   PLoS Computational Biology

Protection from nitrosative stress: A central role for microbial flavohemoglobin

(2012) Michael T. Forrester et al.   FREE RADICAL BIOLOGY AND MEDICINE

The nitric oxide reductase of enterohaemorrhagic Escherichia coli plays an important role for the survival within macrophages

(2012) Takeshi Shimizu et al.   MOLECULAR MICROBIOLOGY

Nitrous oxide production and consumption: regulation of gene expression by gas-sensitive transcription factors

(2012) S. Spiro   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The potential of nitric oxide releasing therapies as antimicrobial agents

(2012) David O. Schairer et al.   Virulence

Synergistic Drug Combinations for Tuberculosis Therapy Identified by a Novel High-Throughput Screen

(2011) Santiago Ramón-García et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Update on the use of pramipexole in the treatment of Parkinson’s disease

(2011) Radu Constantinescu   Neuropsychiatric Disease and Treatment

Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study

(2010) Karthikeyan K Kumarasamy et al.   LANCET INFECTIOUS DISEASES

Role of flavohemoglobin in combating nitrosative stress in uropathogenic Escherichia coli – Implications for urinary tract infection

(2010) Lovisa Svensson et al.   MICROBIAL PATHOGENESIS

Bacteriophages as potential new therapeutics to replace or supplement antibiotics

(2010) Mzia Kutateladze et al.   TRENDS IN BIOTECHNOLOGY

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

The chemical biology of nitric oxide: Implications in cellular signaling

(2008) Douglas D. Thomas et al.   FREE RADICAL BIOLOGY AND MEDICINE

Synergistic effects of Miconazole and Polymyxin B on microbial pathogens

(2008) Silvia Pietschmann et al.   VETERINARY RESEARCH COMMUNICATIONS

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY