Creating rat hepatocyte organoid as an in vitro model for drug testing

Organoids — Preclinical Models of Human Disease

(2019) Mo Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

The mesenchymal stem cell secretome as an acellular regenerative therapy for liver disease

(2019) Julia Driscoll et al.   JOURNAL OF GASTROENTEROLOGY

The immunoregulation of mesenchymal stem cells plays a critical role in improving the prognosis of liver transplantation

(2019) Chenxia Hu et al.   Journal of Translational Medicine

Extracellular matrix hydrogel therapies: In vivo applications and development

(2018) Martin T. Spang et al.   Acta Biomaterialia

A decade of progress in liver regenerative medicine

(2018) Jingwei Zhang et al.   BIOMATERIALS

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells

(2018) Beatrice Ho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids

(2018) Ran-Ran Zhang et al.   Stem Cell Reports

Metabolic Oscillations in Co-Cultures of Hepatocytes and Mesenchymal Stem Cells: Effects of Seeding Arrangement and Culture Mixing

(2017) Dalia Abdelrahim Alzebdeh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells

(2017) Takanori Takebe et al.   Cell Reports

Organoids as an in vitro model of human development and disease

(2016) Aliya Fatehullah et al.   NATURE CELL BIOLOGY

Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure

(2016) Ewart W. Kuijk et al.   Scientific Reports

A microfluidically perfused three dimensional human liver model

(2015) Knut Rennert et al.   BIOMATERIALS

Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation

(2015) Takanori Takebe et al.   Cell Stem Cell

Optimizing Perfusion-Decellularization Methods of Porcine Livers for Clinical-Scale Whole-Organ Bioengineering

(2015) Qiong Wu et al.   Biomed Research International

Hepatic organoids for microfluidic drug screening

(2014) Sam H. Au et al.   LAB ON A CHIP

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

(2013) Meritxell Huch et al.   NATURE

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Serum-Free Medium and Mesenchymal Stromal Cells Enhance Functionality and Stabilize Integrity of Rat Hepatocyte Spheroids

(2012) Ji Bao et al.   CELL TRANSPLANTATION

Mechanical Signals Trigger Myosin II Redistribution and Mesoderm Invagination in Drosophila Embryos

(2009) P.-A. Pouille et al.   Science Signaling

Maintenance of Human Hepatocyte Function In Vitro by Liver-Derived Extracellular Matrix Gels

(2009) Tiffany L. Sellaro et al.   TISSUE ENGINEERING PART A