Hematogenous Dissemination of Breast Cancer Cells From Lymph Nodes Is Mediated by Tumor MicroEnvironment of Metastasis Doorways

Establishment and Maintenance of the Macrophage Niche

(2020) Martin Guilliams et al.   IMMUNITY

The emerging roles of macrophages in cancer metastasis and response to chemotherapy

(2019) Luis Rivera Sanchez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche

(2019) Isabelle Mondor et al.   IMMUNITY

Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis

(2019) George S. Karagiannis et al.   Jove-Journal of Visualized Experiments

Chemotherapy-Induced Metastasis: Molecular Mechanisms, Clinical Manifestations, Therapeutic Interventions

(2019) George S. Karagiannis et al.   CANCER RESEARCH

Tumor Microenvironment of Metastasis (TMEM) Doorways Are Restricted to the Blood Vessel Endothelium in Both Primary Breast Cancers and Their Lymph Node Metastases

(2019) Ginter et al.   Cancers

Breast cancer metastasis through the lympho-vascular system

(2018) S. David Nathanson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes

(2018) Ikram Ullah et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

(2018) Ethel R. Pereira et al.   SCIENCE

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

(2018) M. Brown et al.   SCIENCE

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Revisiting Seed and Soil: Examining the Primary Tumor and Cancer Cell Foraging in Metastasis

(2017) Amber E. de Groot et al.   MOLECULAR CANCER RESEARCH

The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2 Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors

(2017) Allison S. Harney et al.   MOLECULAR CANCER THERAPEUTICS

A permanent window for the murine lung enables high-resolution imaging of cancer metastasis

(2017) David Entenberg et al.   NATURE METHODS

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

(2017) George S. Karagiannis et al.   Science Translational Medicine

Intratumoral Cancer Cell Intravasation Can Occur Independent of Invasion into the Adjacent Stroma

(2017) Elena I. Deryugina et al.   Cell Reports

Signatures of breast cancer metastasis at a glance

(2016) George S. Karagiannis et al.   JOURNAL OF CELL SCIENCE

Extended Time-lapse Intravital Imaging of Real-time Multicellular Dynamics in the Tumor Microenvironment

(2016) Allison S. Harney et al.   Jove-Journal of Visualized Experiments

TMEM: a novel breast cancer dissemination marker for the assessment of metastatic risk

(2015) Maja H Oktay et al.   Biomarkers in Medicine

Cancer Metastasis: Perivascular Macrophages Under Watch

(2015) E. Kadioglu et al.   Cancer Discovery

Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA

(2015) A. S. Harney et al.   Cancer Discovery

A Flexible Reporter System for Direct Observation and Isolation of Cancer Stem Cells

(2015) Binwu Tang et al.   Stem Cell Reports

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Tumor Microenvironment of Metastasis and Risk of Distant Metastasis of Breast Cancer

(2014) Thomas E. Rohan et al.   JNCI-Journal of the National Cancer Institute

Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGFβ in claudin-low breast tumor cells

(2014) A Patsialou et al.   ONCOGENE

Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration

(2014) J. Pignatelli et al.   Science Signaling

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype

(2014) Bojana Gligorijevic et al.   PLOS BIOLOGY

Tumor-associated macrophages: functional diversity, clinical significance, and open questions

(2013) Subhra K. Biswas et al.   Seminars in Immunopathology

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions

(2011) Damya Laoui et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Tumor Microenvironment of Metastasis in Human Breast Carcinoma: A Potential Prognostic Marker Linked to Hematogenous Dissemination

(2009) B. D. Robinson et al.   CLINICAL CANCER RESEARCH

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

(2009) Alberto Mantovani et al.   HUMAN IMMUNOLOGY

Macrophages define the invasive microenvironment in breast cancer

(2008) Jeffrey W. Pollard   JOURNAL OF LEUKOCYTE BIOLOGY

The “seed and soil” hypothesis revisited

(2008) Isaiah J Fidler et al.   LANCET ONCOLOGY

Intravital imaging of metastatic behavior through a mammary imaging window

(2008) Dmitriy Kedrin et al.   NATURE METHODS