KDM5c Promotes Colon Cancer Cell Proliferation Through the FBXW7-c-Jun Regulatory Axis

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

(2019) Stephanie A. Bien et al.   HUMAN GENETICS

The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism

(2019) Soojeong Chang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

FBW7 suppresses cell proliferation and G2/M cell cycle transition via promoting γ-catenin K63-linked ubiquitylation

(2018) Yu Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine

(2018) Jenny M. Riley et al.   CANCER

Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7in a manner dependent on the kinase GSK-3

(2018) Shogo Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for DNMT3A-mediated de novo DNA methylation

(2018) Zhi-Min Zhang et al.   NATURE

H3K4me2 and WDR5 enriched chromatin interacting long non-coding RNAs maintain transcriptionally competent chromatin at divergent transcriptional units

(2018) Santhilal Subhash et al.   NUCLEIC ACIDS RESEARCH

Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCF Fbw7 Ubiquitin Ligase

(2018) Veronika Csizmok et al.   STRUCTURE

FBXW7: a critical tumor suppressor of human cancers

(2018) Chien-Hung Yeh et al.   Molecular Cancer

KDM5 histone demethylases repress immune response via suppression of STING

(2018) Lizhen Wu et al.   PLOS BIOLOGY

Beyond DNA: the Role of Epigenetics in the Premalignant Progression of Breast Cancer

(2018) Rebecca S. DeVaux et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

CDK5/FBW7-dependent ubiquitination and degradation of EZH2 inhibits pancreatic cancer cell migration and invasion

(2017) Xin Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers

(2017) Tamotsu Sugai et al.   MOLECULAR CARCINOGENESIS

Emerging roles of linker histones in regulating chromatin structure and function

(2017) Dmitry V. Fyodorov et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia

(2017) M P Hanley et al.   ONCOGENE

DNA methylation epigenotype and clinical features of NRAS -mutation(+) colorectal cancer

(2017) Kiyoko Takane et al.   Cancer Medicine

Enhancement of Proliferation and Invasion of Gastric Cancer Cell by KDM5C Via Decrease in p53 Expression

(2016) Liming Xu et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer

(2016) Jennifer M. Spangle et al.   Cell Reports

Histone demethylase JARID1C promotes breast cancer metastasis cells via down regulating BRMS1 expression

(2015) Qin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

(2013) Z. Herceg et al.   CARCINOGENESIS

Epigenetics and Colorectal Cancer Pathogenesis

(2013) Kankana Bardhan et al.   Cancers

STRAP regulates c-Jun ubiquitin-mediated proteolysis and cellular proliferation

(2011) Jennifer Reiner et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure and Mechanisms of Lysine Methylation Recognition by the Chromodomain in Gene Transcription

(2011) Kyoko L. Yap et al.   BIOCHEMISTRY

DNA methylation and histone modifications modulate the β1,3 galactosyltransferase β3Gal-T5 native promoter in cancer cells

(2011) Anna Caretti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Molecular coupling of DNA methylation and histone methylation

(2010) Hideharu Hashimoto et al.   Epigenomics

DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer

(2009) K. Nosho et al.   CLINICAL CANCER RESEARCH

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS