Modulation of Inflammasome and Pyroptosis by Olaparib, a PARP-1 Inhibitor, in the R6/2 Mouse Model of Huntington’s Disease

Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage

(2020) Bin Yuan et al.   Cell Death & Disease

Pyroptotic cell death in the R6/2 mouse model of Huntington’s disease: new insight on the inflammasome

(2020) Emanuela Paldino et al.   Cell Death Discovery

Inflammasomes in neuroinflammatory and neurodegenerative diseases

(2019) Sofie Voet et al.   EMBO Molecular Medicine

PARP inhibition by olaparib alleviates chronic asthma‐associated remodeling features via modulating inflammasome signaling in mice

(2019) Gurupreet S. Sethi et al.   IUBMB LIFE

NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

(2017) Jun Yin et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective Effects of Poly(ADP-ribose)polymerase Inhibitor Olaparib in Transient Cerebral Ischemia

(2016) Fei Teng et al.   NEUROCHEMICAL RESEARCH

Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity

(2016) Jin-Chong Xu et al.   Science Translational Medicine

Poly(ADP-Ribose)Polymerase 1 (PARP-1) Activation and Ca2+ Permeable α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Channels in Post-Ischemic Brain Damage: New Therapeutic Opportunities?

(2015) Elisabetta Gerace et al.   CNS & Neurological Disorders-Drug Targets

PARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington’s Disease

(2015) Antonella Cardinale et al.   PLoS One

Inhibition of poly(ADP-ribosyl)ation in cancer: Old and new paradigms revisited

(2014) Barbara Lupo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Beyond DNA repair, the immunological role of PARP-1 and its siblings

(2013) Maria Manuela Rosado et al.   IMMUNOLOGY

Therapeutic approaches to preventing cell death in Huntington disease

(2012) Anna Kaplan et al.   PROGRESS IN NEUROBIOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Poly(ADP-Ribose) Metabolism in Brain and Its Role in Ischemia Pathology

(2010) Robert Piotr Strosznajder et al.   MOLECULAR NEUROBIOLOGY

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

(2009) Yingfei Wang et al.   EXPERIMENTAL NEUROLOGY

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE