Small-Molecule Chemical Knockdown of MuRF1 in Melanoma Bearing Mice Attenuates Tumor Cachexia Associated Myopathy

Publisher Correction: Partial proteasomal degradation of Lola triggers the male-to-female switch of a dimorphic courtship circuit

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MT‐102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia

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Astrocyte-derived exosomes transfer miR-190b to inhibit oxygen and glucose deprivation-induced autophagy and neuronal apoptosis

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Melatonin decreases M1 polarization via attenuating mitochondrial oxidative damage depending on UCP2 pathway in prorenin-treated microglia

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Doxorubicin Exposure Causes Subacute Cardiac Atrophy Dependent on the Striated Muscle–Specific Ubiquitin Ligase MuRF1

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SMDT1-driven change in mitochondrial dynamics mediate cell apoptosis in PDAC

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Small‐molecule‐mediated chemical knock‐down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure

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ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis

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The combined effect of creatine and resistance training on doxorubicin-induced muscle dysfunction

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MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

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Beneficial Effects of Leucine Supplementation on Criteria for Sarcopenia: A Systematic Review

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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells

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Cancer cachexia: Diagnosis, assessment, and treatment

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Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma

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Cancer-associated cachexia

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Recent advances in research on aspartate β-hydroxylase (ASPH) in pancreatic cancer: A brief update

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Bortezomib-Induced Muscle Toxicity in Multiple Myeloma

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Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions

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Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

(2017) Thomas Scott Bowen et al.   Journal of Cachexia Sarcopenia and Muscle

Syngeneic B16F10 Melanoma Causes Cachexia and Impaired Skeletal Muscle Strength and Locomotor Activity in Mice

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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery

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Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis

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Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas

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ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains

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HBx co-localizes with COXIII in HL-7702 cells to upregulate mitochondrial function and ROS generation

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QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

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Mitochondrial reactive oxygen species production and respiratory complex activity in rats with pressure overload-induced heart failure

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Antibodies to active zone protein ERC1 in Lambert–Eaton myasthenic syndrome

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Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17

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Tubulin Tyrosine Ligase Like 12, a TTLL Family Member with SET- and TTL-Like Domains and Roles in Histone and Tubulin Modifications and Mitosis

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Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

(2011) Cécile Polge et al.   FASEB JOURNAL

Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases

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During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

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Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

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MuRF1-dependent Regulation of Systemic Carbohydrate Metabolism as Revealed from Transgenic Mouse Studies

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MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Muscle RING-Finger Protein-1 (MuRF1) as a Connector of Muscle Energy Metabolism and Protein Synthesis

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