Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons

(2020) Carole Shum et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

(2019) Simon T. Schafer et al.   NATURE NEUROSCIENCE

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

An Exploratory Examination of Neonatal Cytokines and Chemokines as Predictors of Autism Risk: The Early Markers for Autism Study

(2019) Luke S. Heuer et al.   BIOLOGICAL PSYCHIATRY

Maternal and Early Postnatal Immune Activation Produce Dissociable Effects on Neurotransmission in mPFC–Amygdala Circuits

(2018) Yan Li et al.   JOURNAL OF NEUROSCIENCE

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

(2018) Andrew E. Jaffe et al.   NATURE NEUROSCIENCE

Analysis of shared heritability in common disorders of the brain

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Interferon stimulation creates chromatin marks and establishes transcriptional memory

(2018) Rui Kamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

(2018) Michael J. Gandal et al.   SCIENCE

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

DiAna, an ImageJ tool for object-based 3D co-localization and distance analysis

(2017) Jean-François Gilles et al.   METHODS

Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development

(2017) A Kathuria et al.   MOLECULAR PSYCHIATRY

Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder

(2017) M V Lombardo et al.   MOLECULAR PSYCHIATRY

Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder

(2017) Aditi Deshpande et al.   Cell Reports

The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders

(2017) Eva Loth et al.   Molecular Autism

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

(2016) Anthony J. Filiano et al.   NATURE

The interferon-induced antiviral protein PML (TRIM19) promotes the restriction and transcriptional silencing of lentiviruses in a context-specific, isoform-specific fashion

(2016) Nasser Masroori et al.   Retrovirology

Maternal immune activation: Implications for neuropsychiatric disorders

(2016) M. L. Estes et al.   SCIENCE

Perfect timing: splicing and transcription rates in living cells

(2016) Tara Alpert et al.   Wiley Interdisciplinary Reviews-RNA

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Biological insights from 108 schizophrenia-associated genetic loci

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Patches of Disorganization in the Neocortex of Children with Autism

(2014) Rich Stoner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional consequences of schizophrenia candidate miR-137 manipulation in human neural progenitor cells

(2014) Matthew J. Hill et al.   SCHIZOPHRENIA RESEARCH

Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism

(2014) Simone Gupta et al.   Nature Communications

Prenatal Poly(I:C) Exposure and Other Developmental Immune Activation Models in Rodent Systems

(2013) Urs Meyer   BIOLOGICAL PSYCHIATRY

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

MHCI Requires MEF2 Transcription Factors to Negatively Regulate Synapse Density during Development and in Disease

(2013) B. M. Elmer et al.   JOURNAL OF NEUROSCIENCE

Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity

(2013) Erica Korb et al.   NATURE NEUROSCIENCE

The utility of patient specific induced pluripotent stem cells for the modelling of Autistic Spectrum Disorders

(2013) Graham Cocks et al.   PSYCHOPHARMACOLOGY

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)

(2013) Brett S Abrahams et al.   Molecular Autism

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Maternal immune activation causes age- and region-specific changes in brain cytokines in offspring throughout development

(2012) Paula A. Garay et al.   BRAIN BEHAVIOR AND IMMUNITY

Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization

(2012) Tina Bilousova et al.   JOURNAL OF NEUROIMMUNOLOGY

The dendritic tree and brain disorders

(2012) Vaishali A. Kulkarni et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study

(2012) H. O. Atladottir et al.   PEDIATRICS

Modelling schizophrenia using human induced pluripotent stem cells

(2011) Kristen J. Brennand et al.   NATURE

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

(2011) Irina Voineagu et al.   NATURE

MHCI negatively regulates synapse density during the establishment of cortical connections

(2011) Marian W Glynn et al.   NATURE NEUROSCIENCE

Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

(2011) Paula E Goines et al.   Molecular Autism

Gamma Interferon-Dependent Transcriptional Memory via Relocalization of a Gene Locus to PML Nuclear Bodies

(2010) M. Gialitakis et al.   MOLECULAR AND CELLULAR BIOLOGY

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

MHC class I molecules are present both pre- and postsynaptically in the visual cortex during postnatal development and in adulthood

(2010) L. A. Needleman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic Trioxide Controls the Fate of the PML-RAR  Oncoprotein by Directly Binding PML

(2010) X. W. Zhang et al.   SCIENCE

NovelPTENmutations in neurodevelopmental disorders and macrocephaly

(2009) A Orrico et al.   CLINICAL GENETICS

Common variants on chromosome 6p22.1 are associated with schizophrenia

(2009) Jianxin Shi et al.   NATURE

The tumor suppressor Pml regulates cell fate in the developing neocortex

(2009) Tarik Regad et al.   NATURE NEUROSCIENCE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols