Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing
Authors
Keywords
-
Journal
Science Advances
Volume 6, Issue 36, Pages eabb9011
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-09-03
DOI
10.1126/sciadv.abb9011
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis
- (2019) Chiara Indiani et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients
- (2019) Antonino Cassotta et al. NATURE MEDICINE
- Antimicrobial Treatment of Staphylococcus aureus in Patients With Cystic Fibrosis
- (2019) Susanna Esposito et al. Frontiers in Pharmacology
- SampPick: Selection of a Cohort of Subjects Matching a Population HLA Distribution
- (2019) Joseph R. McGill et al. Frontiers in Immunology
- DisruPPI: structure-based computational redesign algorithm for protein binding disruption
- (2018) Yoonjoo Choi et al. BIOINFORMATICS
- Influence of multidrug resistant organisms on the outcome of diabetic foot infection
- (2018) Nese Saltoglu et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Evaluating and Mitigating the Immunogenicity of Therapeutic Proteins
- (2018) Zuben E. Sauna et al. TRENDS IN BIOTECHNOLOGY
- Development of Phage Lysins as Novel Therapeutics: A Historical Perspective
- (2018) Vincent Fischetti Viruses-Basel
- Are Phage Lytic Proteins the Secret Weapon To Kill Staphylococcus aureus?
- (2018) Diana Gutiérrez et al. mBio
- Effects of Phage Endolysin SAL200 Combined with Antibiotics on Staphylococcus aureus Infection
- (2018) Nak-Hyun Kim et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity
- (2017) Regina S. Salvat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Post hoc assessment of the immunogenicity of bioengineered factor VIIa demonstrates the use of preclinical tools
- (2017) Kasper Lamberth et al. Science Translational Medicine
- The effect of diabetes mellitus on outcomes of patients with nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus: data from a prospective double-blind clinical trial comparing treatment with linezolid versus vancomycin
- (2016) Ozlem Equils et al. BMC INFECTIOUS DISEASES
- Design and engineering of deimmunized biotherapeutics
- (2016) Karl E Griswold et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The Global RegulonsarARegulates β-Lactam Antibiotic Resistance in Methicillin-ResistantStaphylococcus aureusIn Vitro and in Endovascular Infections
- (2016) Liang Li et al. JOURNAL OF INFECTIOUS DISEASES
- Alternatives to antibiotics—a pipeline portfolio review
- (2016) Lloyd Czaplewski et al. LANCET INFECTIOUS DISEASES
- Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics
- (2016) Marisa K. Joubert et al. PLoS One
- Depletion of T Cell Epitopes in Lysostaphin Mitigates Anti-Drug Antibody Response and Enhances Antibacterial Efficacy In Vivo
- (2015) Hongliang Zhao et al. CHEMISTRY & BIOLOGY
- Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management
- (2015) Steven Y. C. Tong et al. CLINICAL MICROBIOLOGY REVIEWS
- Structure-based design of combinatorial mutagenesis libraries
- (2015) Deeptak Verma et al. PROTEIN SCIENCE
- Gene and Protein Sequence Optimization for High-Level Production of Fully Active and Aglycosylated Lysostaphin in Pichia pastoris
- (2014) H. Zhao et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- PEG — A versatile conjugating ligand for drugs and drug delivery systems
- (2014) Atul Kolate et al. JOURNAL OF CONTROLLED RELEASE
- Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia
- (2013) Raymond Schuch et al. JOURNAL OF INFECTIOUS DISEASES
- Bacteriophage endolysins as novel antimicrobials
- (2012) Mathias Schmelcher et al. Future Microbiology
- DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP)
- (2012) Nathali Kaushansky et al. Journal of Neuroinflammation
- Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A
- (2012) R. Mazor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional classification of class II human leukocyte antigen (HLA) molecules reveals seven different supertypes and a surprising degree of repertoire sharing across supertypes
- (2011) Jason Greenbaum et al. IMMUNOGENETICS
- PEGylating a bacteriophage endolysin inhibits its bactericidal activity
- (2011) Gregory Resch et al. AMB Express
- Influence of interferon-beta therapy switching on neutralizing antibody titres: results from the Austrian Switch Study
- (2009) Claudia Gneiss et al. Multiple Sclerosis Journal
- Waves of resistance: Staphylococcus aureus in the antibiotic era
- (2009) Henry F. Chambers et al. NATURE REVIEWS MICROBIOLOGY
- Pharmacokinetics of Immunoglobulin Administered via Intravenous or Subcutaneous Routes
- (2008) Francisco A. Bonilla IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search