Oxymatrine Inhibits Colorectal Cancer Metastasis via Attenuating PKM2-Mediated Aerobic Glycolysis

Oxymatrine Inhibits Proliferation and Migration of Vulvar Squamous Cell Carcinoma Cells via Attenuation of the RAS/RAF/MEK/ERK Pathway

(2020) Yanshi Wang et al.   Cancer Management and Research

Oxymatrine Attenuates Tumor Growth and Deactivates STAT5 Signaling in a Lung Cancer Xenograft Model

(2019) Young Jung et al.   Cancers

Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis

(2019) Chong Chen et al.   ONCOGENE

Treatment of metastatic colorectal cancer: innovations in surgical techniques

(2019) James P. Andrade et al.   JOURNAL OF SURGICAL ONCOLOGY

Biomarker-guided therapy for colorectal cancer: strength in complexity

(2019) Anita Sveen et al.   Nature Reviews Clinical Oncology

Targeted therapy for colorectal cancer metastases: A review of current methods of molecularly targeted therapy and the use of tumor biomarkers in the treatment of metastatic colorectal cancer

(2019) Sorbarikor Piawah et al.   CANCER

Oxymatrine reverses 5‑fluorouracil resistance by inhibition of colon cancer cell epithelial‑mesenchymal transition and NF‑κB signaling in�vitro

(2019) Li Liang et al.   Oncology Letters

Oxymatrine Inhibits the Proliferation and Invasion of Breast Cancer Cells via the PI3K Pathway

(2019) Lin Guo et al.   Cancer Management and Research

Mutations of key driver genes in colorectal cancer progression and metastasis

(2018) Dongdong Huang et al.   CANCER AND METASTASIS REVIEWS

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

(2018) Pierre-Benoit Ancey et al.   FEBS Journal

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Oxymatrine and Cisplatin Synergistically Enhance Anti-tumor Immunity of CD8+ T Cells in Non-small Cell Lung Cancer

(2018) Jin Ye et al.   Frontiers in Oncology

Oxymatrine induces nasopharyngeal cancer cell death through inhibition of PI3K/AKT and NF-κB pathways

(2017) Zhili Ni et al.   Molecular Medicine Reports

Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis

(2017) Oliver G McDonald et al.   NATURE GENETICS

Oxymatrine inhibits proliferation of human bladder cancer T24 cells by inducing apoptosis and cell cycle arrest

(2017) Shun Li et al.   Oncology Letters

Oxymatrine inhibits non-small cell lung cancer via suppression of EGFR signaling pathway

(2017) Wei Li et al.   Cancer Medicine

Glycolysis Inhibitors for Anticancer Therapy: A Review of Recent Patents

(2016) Huaming Sheng et al.   Recent Patents on Anti-Cancer Drug Discovery

Anti-tumor activities of active ingredients in Compound Kushen Injection

(2015) Wei Wang et al.   ACTA PHARMACOLOGICA SINICA

Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases

(2015) Lydia G. M. van der Geest et al.   CLINICAL & EXPERIMENTAL METASTASIS

Anticancer Advances of Matrine and Its Derivatives

(2015) Jianping Yong et al.   CURRENT PHARMACEUTICAL DESIGN

Oxymatrine inhibits the proliferation of prostate cancer cells in vitro and in vivo

(2015) CUNZAO WU et al.   Molecular Medicine Reports

Patterns of metachronous metastases after curative treatment of colorectal cancer

(2014) Yvette R.B.M. van Gestel et al.   Cancer Epidemiology

Pyruvate kinase M2 and cancer: an updated assessment

(2014) Mohd Askandar Iqbal et al.   FEBS LETTERS

Oxymatrine induces apoptosis in human cervical cancer cells through guanine nucleotide depletion

(2013) Mu Li et al.   ANTI-CANCER DRUGS

PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells

(2013) Yuhui Jiang et al.   MOLECULAR CELL

Fibronectin-induced VEGF receptor and calcium channel transactivation stimulate GLUT-1 synthesis and trafficking through PPARγ and TC10 in mouse embryonic stem cells

(2013) Han Na Suh et al.   Stem Cell Research

Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression

(2012) Michael S. Goldberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Oxymatrine induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome c

(2011) Qi Ling et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Identification of small molecule inhibitors of pyruvate kinase M2

(2009) Matthew G. Vander Heiden et al.   BIOCHEMICAL PHARMACOLOGY

Improved Survival in Metastatic Colorectal Cancer Is Associated With Adoption of Hepatic Resection and Improved Chemotherapy

(2009) Scott Kopetz et al.   JOURNAL OF CLINICAL ONCOLOGY

Evaluation of SubstitutedN,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase

(2009) Matthew B. Boxer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells

(2009) J. Yun et al.   SCIENCE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL