Aiming for the Sweet Spot: Glyco-Immune Checkpoints and γδ T Cells in Targeted Immunotherapy
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aiming for the Sweet Spot: Glyco-Immune Checkpoints and γδ T Cells in Targeted Immunotherapy
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-09-29
DOI
10.3389/fimmu.2020.564499
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
- (2020) Marc Rigau et al. SCIENCE
- A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
- (2020) Jérôme Le Nours et al. SCIENCE
- Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
- (2020) Mohindar M. Karunakaran et al. IMMUNITY
- O-acetylated Gangliosides as Targets for Cancer Immunotherapy
- (2020) Sumeyye Cavdarli et al. Cells
- Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
- (2019) Jun Wang et al. NATURE MEDICINE
- Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma
- (2019) Kim C. M. Santegoets et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Siglec-9 Regulates an Effector Memory CD8+ T-cell Subset That Congregates in the Melanoma Tumor Microenvironment
- (2019) Quentin Haas et al. Cancer Immunology Research
- Protein Glycosylation and Tumor Microenvironment Alterations Driving Cancer Hallmarks
- (2019) Andreia Peixoto et al. Frontiers in Oncology
- CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy
- (2019) Amira A. Barkal et al. NATURE
- Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
- (2019) Zsolt Sebestyen et al. NATURE REVIEWS DRUG DISCOVERY
- Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen
- (2019) Carrie R. Willcox et al. IMMUNITY
- GD2-targeted chimeric antigen receptor T cells prevent metastasis formation by elimination of breast cancer stem-like cells
- (2019) Christian M. Seitz et al. OncoImmunology
- Immune checkpoint blockade therapy for cancer: An overview of FDA-approved immune checkpoint inhibitors
- (2018) Kristian M. Hargadon et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Developed NK-92MI Cell Line with Siglec-7neg Phenotype Exhibits High and Sustainable Cytotoxicity against Leukemia Cells
- (2018) Chin-Han Huang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation
- (2018) Anna Capsomidis et al. MOLECULAR THERAPY
- Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas
- (2018) Christopher W. Mount et al. NATURE MEDICINE
- Glycointeractions in bacterial pathogenesis
- (2018) Jessica Poole et al. NATURE REVIEWS MICROBIOLOGY
- Working in “NK Mode”: Natural Killer Group 2 Member D and Natural Cytotoxicity Receptors in Stress-Surveillance by γδ T Cells
- (2018) Bruno Silva-Santos et al. Frontiers in Immunology
- Improving the Efficiency of Vγ9Vδ2 T-Cell Immunotherapy in Cancer
- (2018) Timm Hoeres et al. Frontiers in Immunology
- Chemistry-Driven Glycoscience
- (2018) Laura L. Kiessling BIOORGANIC & MEDICINAL CHEMISTRY
- Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells
- (2018) Michal A. Stanczak et al. JOURNAL OF CLINICAL INVESTIGATION
- PD-1 signaling modulates interferon-γ production by Gamma Delta (γδ) T-Cells in response to leukemia
- (2018) Timm Hoeres et al. OncoImmunology
- Clonal selection in the human Vδ1 T cell repertoire indicates γδ TCR-dependent adaptive immune surveillance
- (2017) Martin S. Davey et al. Nature Communications
- Biological roles of glycans
- (2016) Ajit Varki GLYCOBIOLOGY
- IL-17–Producing Innate and Pathogen-Specific Tissue Resident Memory γδ T Cells Expand in the Lungs ofBordetella pertussis–Infected Mice
- (2016) Alicja Misiak et al. JOURNAL OF IMMUNOLOGY
- Progenitor/Stem Cell Markers in Brain Adjacent to Glioblastoma: GD3 Ganglioside and NG2 Proteoglycan Expression
- (2016) Gina Lama et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade
- (2016) Tessa Gargett et al. MOLECULAR THERAPY
- The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9
- (2016) Richard Beatson et al. NATURE IMMUNOLOGY
- Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents, and young adults
- (2016) Konstantin Dobrenkov et al. PEDIATRIC BLOOD & CANCER
- Precision glycocalyx editing as a strategy for cancer immunotherapy
- (2016) Han Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells
- (2016) Maurizio Perdicchio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Clinicopathological and prognostic significance of sialyl Lewis X overexpression in patients with cancer: a meta-analysis
- (2016) Wei Gao et al. OncoTargets and Therapy
- Targeting Selectins and Their Ligands in Cancer
- (2016) Alessandro Natoni et al. Frontiers in Oncology
- Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment
- (2016) Sara M. Elkashef et al. Scientific Reports
- Targeted Delivery of a Sialic Acid-Blocking Glycomimetic to Cancer Cells Inhibits Metastatic Spread
- (2015) Christian Büll et al. ACS Nano
- Sialic acids in cancer biology and immunity
- (2015) Oliver M T Pearce et al. GLYCOBIOLOGY
- Enhanced expression of polysialic acid correlates with malignant phenotype in breast cancer cell lines and clinical tissue samples
- (2015) XIN WANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase
- (2015) Yuki Ohkawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma
- (2015) Alfred L. Garfall et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ligands Binding to Cell Surface Ganglioside GD2 Cause Src-Dependent Activation of N-Methyl-D-Aspartate Receptor Signaling and Changes in Cellular Morphology
- (2015) Wenyong Tong et al. PLoS One
- Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire
- (2015) Tanya Dimova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
- (2015) David L. Porter et al. Science Translational Medicine
- Anergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma
- (2015) Barbara Castella et al. OncoImmunology
- Immunoreactivity of the 14F7 Mab raised againstN-Glycolyl GM3 Ganglioside in retinoblastoma tumours
- (2014) Ana Vanesa Torbidoni et al. ACTA OPHTHALMOLOGICA
- Ganglioside GD2 in reception and transduction of cell death signal in tumor cells
- (2014) Igor I Doronin et al. BMC CANCER
- Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles
- (2014) Cristina Tringali et al. BMC CANCER
- Sialic Acids Sweeten a Tumor's Life
- (2014) C. Bull et al. CANCER RESEARCH
- Gangliosides Drive the Tumor Infiltration and Function of Myeloid-Derived Suppressor Cells
- (2014) A. Wondimu et al. CANCER RESEARCH
- Increased expression of MUC1 and sialyl Lewis antigens in different areas of clear renal cell carcinoma
- (2014) Małgorzata Borzym-Kluczyk et al. Clinical and Experimental Nephrology
- Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity
- (2014) G.-Y. Chen et al. GLYCOBIOLOGY
- The Intracellular B30.2 Domain of Butyrophilin 3A1 Binds Phosphoantigens to Mediate Activation of Human Vγ9Vδ2 T Cells
- (2014) Andrew Sandstrom et al. IMMUNITY
- Interactions between Siglec-7/9 receptors and ligands influence NK cell–dependent tumor immunosurveillance
- (2014) Camilla Jandus et al. JOURNAL OF CLINICAL INVESTIGATION
- Siglecs Induce Tolerance to Cell Surface Antigens by BIM-Dependent Deletion of the Antigen-Reactive B Cells
- (2014) Matthew S. Macauley et al. JOURNAL OF IMMUNOLOGY
- Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
- (2014) Shannon L. Maude et al. NEW ENGLAND JOURNAL OF MEDICINE
- GD3 synthase regulates epithelial–mesenchymal transition and metastasis in breast cancer
- (2014) T R Sarkar et al. ONCOGENE
- Molecular Recognition of Gangliosides and Their Potential for Cancer Immunotherapies
- (2014) Ute Krengel et al. Frontiers in Immunology
- Clinical Applications of Gamma Delta T Cells with Multivalent Immunity
- (2014) Drew C. Deniger et al. Frontiers in Immunology
- γδ T cells for cancer immunotherapy
- (2014) Jonathan PH Fisher et al. OncoImmunology
- Tumor gangliosides accelerate murine tumor angiogenesis
- (2013) Yihui Liu et al. ANGIOGENESIS
- Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells
- (2013) Adrienne M. Luoma et al. IMMUNITY
- Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis
- (2013) Matthew S. Macauley et al. JOURNAL OF CLINICAL INVESTIGATION
- Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human V 3 T Cells
- (2013) B. A. Mangan et al. JOURNAL OF IMMUNOLOGY
- Targeting Aberrant Sialylation in Cancer Cells Using a Fluorinated Sialic Acid Analog Impairs Adhesion, Migration, and In Vivo Tumor Growth
- (2013) C. Bull et al. MOLECULAR CANCER THERAPEUTICS
- Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion
- (2013) Jason E Hudak et al. Nature Chemical Biology
- CD1d-lipid antigen recognition by the γδ TCR
- (2013) Adam P Uldrich et al. NATURE IMMUNOLOGY
- Estradiol Represses the GD3 Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter
- (2013) Marie Bobowski et al. PLoS One
- Early IFN-Gamma Production after YF 17D Vaccine Virus Immunization in Mice and Its Association with Adaptive Immune Responses
- (2013) Patrícia C. C. Neves et al. PLoS One
- Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells
- (2013) Y.-J. Liang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor cell recognition by γδ T lymphocytes
- (2013) Daniel V. Correia et al. OncoImmunology
- Glycobiology of immune responses
- (2012) Gabriel A. Rabinovich et al. Annals of the New York Academy of Sciences
- Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human T-cell subset
- (2012) C. Harly et al. BLOOD
- The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting
- (2012) S Kailayangiri et al. BRITISH JOURNAL OF CANCER
- Molecular Identification of GD3 as a Suppressor of the Innate Immune Response in Ovarian Cancer
- (2012) T. J. Webb et al. CANCER RESEARCH
- Detection of N-glycolyated gangliosides in non-small-cell lung cancer using GMR8 monoclonal antibody
- (2012) Nobuyoshi Hayashi et al. CANCER SCIENCE
- Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3
- (2012) Hidenobu Shibuya et al. CANCER SCIENCE
- Diversity of γδ T-cell antigens
- (2012) Willi K Born et al. Cellular & Molecular Immunology
- What lessons can be learned from γδ T cell-based cancer immunotherapy trials?
- (2012) Jean-Jacques Fournié et al. Cellular & Molecular Immunology
- The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vδ1 TCR
- (2012) Li Bai et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The ganglioside GD2 induces the constitutive activation of c-Met in MDA-MB-231 breast cancer cells expressing the GD3 synthase
- (2012) Aurélie Cazet et al. GLYCOBIOLOGY
- The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF- secretion from monocytes/macrophages through the DAP12-Syk pathway
- (2012) R. Takamiya et al. GLYCOBIOLOGY
- Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
- (2012) Venkata Lokesh Battula et al. JOURNAL OF CLINICAL INVESTIGATION
- Accumulation of Unusual Gangliosides GQ3 and GP3 in Breast Cancer Cells Expressing the GD3 Synthase
- (2012) Agata Steenackers et al. MOLECULES
- Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours
- (2011) A J Nicol et al. BRITISH JOURNAL OF CANCER
- Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells
- (2011) Tadaaki Yamada et al. CANCER SCIENCE
- Detection of N-Glycolyl GM3 Ganglioside in Neuroectodermal Tumors by Immunohistochemistry: An Attractive Vaccine Target for Aggressive Pediatric Cancer
- (2011) Alejandra M. Scursoni et al. Clinical & Developmental Immunology
- Expression of the neural cell adhesion molecule and polysialic acid in human neuroblastoma cell lines
- (2011) Ursula Valentiner INTERNATIONAL JOURNAL OF ONCOLOGY
- NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
- (2011) Ruth Esser et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma
- (2011) Suzanne M. Birks et al. NEURO-ONCOLOGY
- Cancer vaccines and carbohydrate epitopes
- (2011) Jamie Heimburg-Molinaro et al. VACCINE
- A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics
- (2010) Haike Ghazarian et al. ACTA HISTOCHEMICA
- The MHC class Ib protein ULBP1 is a nonredundant determinant of leukemia/lymphoma susceptibility to T-cell cytotoxicity
- (2010) T. Lanca et al. BLOOD
- Anti-GD2 Antibody Therapy for GD2-Expressing Tumors
- (2010) F. Navid et al. CURRENT CANCER DRUG TARGETS
- Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation
- (2010) R. P. Muia et al. GLYCOBIOLOGY
- Shedding of GD2 ganglioside in patients with retinoblastoma
- (2010) Jacques Portoukalian et al. INTERNATIONAL JOURNAL OF CANCER
- Sialylation of 3-Methylcholanthrene-Induced Fibrosarcoma Determines Antitumor Immune Responses during Immunoediting
- (2010) M. Cohen et al. JOURNAL OF IMMUNOLOGY
- Carbohydrate vaccines: developing sweet solutions to sticky situations?
- (2010) Rena D. Astronomo et al. NATURE REVIEWS DRUG DISCOVERY
- Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma
- (2010) Alice L. Yu et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD8+ gamma-delta TCR+ and CD4+ T cells produce IFN-γ at 5–7 days after yellow fever vaccination in Indian rhesus macaques, before the induction of classical antigen-specific T cell responses
- (2010) Patrícia C.C. Neves et al. VACCINE
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- GM3 synthase overexpression results in reduced cell motility and in caveolin-1 upregulation in human ovarian carcinoma cells
- (2009) A. Prinetti et al. GLYCOBIOLOGY
- GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
- (2009) Renata Sano et al. MOLECULAR CELL
- CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets
- (2009) Julie C Ribot et al. NATURE IMMUNOLOGY
- Detection and Characterization of N-Glycolyated Gangliosides in Wilms Tumor by Immunohistochemistry
- (2009) Alejandra M. Scursoni et al. PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
- Cross-presenting human T cells induce robust CD8+ T cell responses
- (2009) M. Brandes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GM1 and Tumor Necrosis Factor- , Overexpressed in Renal Cell Carcinoma, Synergize to Induce T-Cell Apoptosis
- (2008) T. Das et al. CANCER RESEARCH
- Fine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand
- (2008) Jun-Eui Park et al. IMMUNOLOGY
- Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis
- (2008) Jessica Strid et al. NATURE IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search