Choice of Nanovaccine Delivery Mode Has Profound Impacts on the Intralymph Node Spatiotemporal Distribution and Immunotherapy Efficacy

Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination

(2020) Xiaobo Xi et al.   Science Advances

A biodegradable thermosensitive hydrogel vaccine for cancer immunotherapy

(2020) Fan Yang et al.   Applied Materials Today

Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

(2019) Wenwen Yue et al.   Nature Communications

Thermal-Responsive Carbon Monoxide (CO) Delivery Expedites Metabolic Exhaustion of Cancer Cells toward Reversal of Chemotherapy Resistance

(2019) Yongjuan Li et al.   ACS Central Science

Material design for lymph node drug delivery

(2019) Alex Schudel et al.   Nature Reviews Materials

Macroscale biomaterials strategies for local immunomodulation

(2019) Maxence O. Dellacherie et al.   Nature Reviews Materials

Microfluidic Sonication To Assemble Exosome Membrane-Coated Nanoparticles for Immune Evasion-Mediated Targeting

(2019) Chao Liu et al.   NANO LETTERS

Microneedle-based delivery devices for cancer therapy: A review

(2019) André F. Moreira et al.   PHARMACOLOGICAL RESEARCH

Bioengineering Bacterial Vesicle-Coated Polymeric Nanomedicine for Enhanced Cancer Immunotherapy and Metastasis Prevention

(2019) Qi Chen et al.   NANO LETTERS

Cancer Cell Membrane-Coated Adjuvant Nanoparticles with Mannose Modification for Effective Anticancer Vaccination

(2018) Rong Yang et al.   ACS Nano

“Minimalist” Nanovaccine Constituted from Near Whole Antigen for Cancer Immunotherapy

(2018) Kun Wang et al.   ACS Nano

Injectable polypeptide hydrogel for dual-delivery of antigen and TLR3 agonist to modulate dendritic cells in vivo and enhance potent cytotoxic T-lymphocyte response against melanoma

(2018) Huijuan Song et al.   BIOMATERIALS

Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination

(2018) Yufei Xia et al.   NATURE MATERIALS

Mesoporous Silica as a Versatile Platform for Cancer Immunotherapy

(2018) Thanh Loc Nguyen et al.   ADVANCED MATERIALS

Reprogramming Exosomes as Nanoscale Controllers of Cellular Immunity

(2018) Qinqin Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic nanovaccines for immunotherapy

(2017) Min Luo et al.   JOURNAL OF CONTROLLED RELEASE

Encapsulation of two different TLR ligands into liposomes confer protective immunity and prevent tumor development

(2017) Banu Bayyurt et al.   JOURNAL OF CONTROLLED RELEASE

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

(2017) Alexander C. Huang et al.   NATURE

A STING-activating nanovaccine for cancer immunotherapy

(2017) Min Luo et al.   Nature Nanotechnology

Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy

(2017) Guizhi Zhu et al.   Nature Communications

Exosome-based tumor antigens–adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA

(2016) Masaki Morishita et al.   BIOMATERIALS

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Adjuvant-Loaded Subcellular Vesicles Derived From Disrupted Cancer Cells for Cancer Vaccination

(2016) Alexander S. Cheung et al.   Small

Cell Membrane Capsules for Encapsulation of Chemotherapeutic and Cancer Cell Targeting in Vivo

(2015) Li-Hua Peng et al.   ACS Applied Materials & Interfaces

Engineering Polymer Hydrogel Nanoparticles for Lymph Node-Targeted Delivery

(2015) Stefaan De Koker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Nanoparticles for Vaccines and Immunotherapy

(2015) Darrell J. Irvine et al.   CHEMICAL REVIEWS

Novel hydrogel adjuvant based on quaternized chitosan for H5N1 split vaccine

(2015) Jie Wu et al.   JOURNAL OF CONTROLLED RELEASE

Single-injection vaccines: Progress, challenges, and opportunities

(2015) Kevin J. McHugh et al.   JOURNAL OF CONTROLLED RELEASE

Immunomodulatory spherical nucleic acids

(2015) Aleksandar F. Radovic-Moreno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Injectable cryogel-based whole-cell cancer vaccines

(2015) Sidi A. Bencherif et al.   Nature Communications

Nanogel-Based Immunologically Stealth Vaccine Targets Macrophages in the Medulla of Lymph Node and Induces Potent Antitumor Immunity

(2014) Daisuke Muraoka et al.   ACS Nano

Immunomodulatory properties of the vaccine adjuvant alum

(2014) Ewa Oleszycka et al.   CURRENT OPINION IN IMMUNOLOGY

Structure-based programming of lymph-node targeting in molecular vaccines

(2014) Haipeng Liu et al.   NATURE

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

(2014) Jaeyun Kim et al.   NATURE BIOTECHNOLOGY

‘Multicopy Multivalent’ Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines

(2013) Alison L. Parry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose

(2013) A. de Titta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microneedles for drug and vaccine delivery

(2012) Yeu-Chun Kim et al.   ADVANCED DRUG DELIVERY REVIEWS

Thermal-sensitive hydrogel as adjuvant-free vaccine delivery system for H5N1 intranasal immunization

(2011) Youbin Wu et al.   BIOMATERIALS

From Vaccines to Memory and Back

(2010) Federica Sallusto et al.   IMMUNITY

Heterologous prime–boost vaccination

(2009) Shan Lu   CURRENT OPINION IN IMMUNOLOGY

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice

(2009) O. A. Ali et al.   Science Translational Medicine

Nanoparticles target distinct dendritic cell populations according to their size

(2008) Vania Manolova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY