Integrated analysis of the transcriptome-wide m6A methylome in preeclampsia and healthy control placentas

Epigenome-wide association data implicate fetal/maternal adaptations contributing to clinical outcomes in preeclampsia

(2019) Teng Wang et al.   Epigenomics

Pre-eclampsia: pathophysiology and clinical implications

(2019) Graham J Burton et al.   BMJ-British Medical Journal

Single-base mapping of m6A by an antibody-independent method

(2019) Zhang Zhang et al.   Science Advances

Epitranscriptomic profiling in human placenta: N6‐methyladenosine modification at the 5′‐untranslated region is related to fetal growth and preeclampsia

(2019) Kosuke Taniguchi et al.   FASEB JOURNAL

Targeting signalling pathways and the immune microenvironment of cancer stem cells — a clinical update

(2019) Joseph A. Clara et al.   Nature Reviews Clinical Oncology

Pathophysiology of placental-derived fetal growth restriction

(2018) Graham J. Burton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors

(2018) Nithya Krishnamurthy et al.   CANCER TREATMENT REVIEWS

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation

(2018) Huilin Huang et al.   NATURE CELL BIOLOGY

Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in zebrafish

(2018) Janina Müller-Deile et al.   Scientific Reports

Mining DNA methylation alterations towards a classification of placental pathologies

(2017) Samantha L Wilson et al.   HUMAN MOLECULAR GENETICS

Wnt/β-catenin signaling pathway in trophoblasts and abnormal activation in preeclampsia

(2017) Zhan Zhang et al.   Molecular Medicine Reports

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

(2017) Raghu R Edupuganti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

(2017) Nian Liu et al.   NUCLEIC ACIDS RESEARCH

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Down-regulated long non-coding RNA-ATB in preeclampsia and its effect on suppressing migration, proliferation, and tube formation of trophoblast cells

(2017) Xijing Liu et al.   PLACENTA

Early- and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn

(2017) Emilie M. Herzog et al.   PLACENTA

Sphingolipids as a new factor in the pathomechanism of preeclampsia – Mass spectrometry analysis

(2017) Karol Charkiewicz et al.   PLoS One

N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis

(2017) Raghu R Edupuganti et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The roles of microRNAs in regulation of mammalian spermatogenesis

(2017) Xiaoxu Chen et al.   Journal of Animal Science and Biotechnology

RNA Regulations and Functions Decoded by Transcriptome-wide RNA Structure Probing

(2017) Meiling Piao et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

DNA methylation profiles in preeclampsia and healthy control placentas

(2016) Kristen R. Yeung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing

(2016) Jin-zhao Ma et al.   HEPATOLOGY

PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases

(2016) Emanuela Veras et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Pre-eclampsia

(2016) Ben W J Mol et al.   LANCET

Gene expression profiling reveals different molecular patterns in G-protein coupled receptor signaling pathways between early- and late-onset preeclampsia

(2016) Mengmeng Liang et al.   PLACENTA

Primate-specific miR-515 family members inhibit key genes in human trophoblast differentiation and are upregulated in preeclampsia

(2016) Ming Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Gestational Diabetes Mellitus Is Associated With Changes in the Concentration and Bioactivity of Placenta-Derived Exosomes in Maternal Circulation Across Gestation

(2015) Carlos Salomon et al.   DIABETES

RNAN6-methyladenosine methylation in post-transcriptional gene expression regulation

(2015) Yanan Yue et al.   GENES & DEVELOPMENT

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Higher expression of HSP70 and LOX-1 in the placental tissues of pre-eclampsia pregnancies

(2014) Abdolkarim Sheikhi et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

The dynamic epitranscriptome: N6-methyladenosine and gene expression control

(2014) Kate D. Meyer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

IFPA Senior Award Lecture: Making sense of pre-eclampsia – Two placental causes of preeclampsia?

(2014) C.W. Redman et al.   PLACENTA

Mutation in Folate Metabolism Causes Epigenetic Instability and Transgenerational Effects on Development

(2013) Nisha Padmanabhan et al.   CELL

Parental history of type 2 diabetes, TCF7L2 variant and lower insulin secretion are associated with incident hypertension. Data from the DESIR and RISC cohorts

(2013) Fabrice Bonnet et al.   DIABETOLOGIA

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

The ever growing complexity of placental epigenetics – Role in adverse pregnancy outcomes and fetal programming

(2012) B. Novakovic et al.   PLACENTA

Serum heat shock protein 70 levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in women with preeclampsia

(2011) Attila Molvarec et al.   CLINICA CHIMICA ACTA

Gene expression profiling of placentae from women with early- and late-onset pre-eclampsia: down-regulation of the angiogenesis-related genes ACVRL1 and EGFL7 in early-onset disease

(2011) K. Junus et al.   MOLECULAR HUMAN REPRODUCTION

Differential Placental Gene Expression in Severe Preeclampsia

(2009) V. Sitras et al.   PLACENTA