Berberine Improves Inflammatory Responses of Diabetes Mellitus in Zucker Diabetic Fatty Rats and Insulin-Resistant HepG2 Cells through the PPM1B Pathway

Oxymatrine ameliorates insulin resistance in rats with type 2 diabetes by regulating the expression of KSRP, PETN, and AKT in the liver

(2019) Mei‐Ling Zuo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Berberine Protects against NEFA-Induced Impairment of Mitochondrial Respiratory Chain Function and Insulin Signaling in Bovine Hepatocytes

(2018) Zhen Shi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine attenuates pulmonary arterial hypertension via protein phosphatase 2A signaling pathway both in vivo and in vitro

(2018) Jie Luo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity

(2018) Emad H.M. Hassanein et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA Single Nucleotide Polymorphisms and Diabetes Mellitus: A Comprehensive Review

(2018) Yanfen Zhang et al.   CLINICAL GENETICS

Exosomes and diabetes

(2018) Carlos Castaño et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The Effect of Berberine on Polycystic Ovary Syndrome Patients with Insulin Resistance (PCOS-IR): A Meta-Analysis and Systematic Review

(2018) Meng-Fei Li et al.   Evidence-based Complementary and Alternative Medicine

Berberine alleviates oxidized low-density lipoprotein-induced macrophage activation by downregulating galectin-3 via the NF-κB and AMPK signaling pathways

(2018) ChongZhe Pei et al.   PHYTOTHERAPY RESEARCH

Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease

(2017) Li Zhao et al.   BMC Endocrine Disorders

Berberine relieves insulin resistance via the cholinergic anti-inflammatory pathway in HepG2 cells

(2016) Fen Li et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Identification and Verification of Potential Therapeutic Target Genes in Berberine-Treated Zucker Diabetic Fatty Rats through Bioinformatics Analysis

(2016) Yang Sheng Wu et al.   PLoS One

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

(2016) M. Johanns et al.   Nature Communications

PPARγ agonists regulate bidirectional transport of amyloid-β across the blood-brain barrier and hippocampus plasticity indb/dbmice

(2015) Hao Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuronal LRP1 Regulates Glucose Metabolism and Insulin Signaling in the Brain

(2015) C.-C. Liu et al.   JOURNAL OF NEUROSCIENCE

miR-186 downregulates protein phosphatase PPM1B in bladder cancer and mediates G1-S phase transition

(2015) Jianan Yang et al.   TUMOR BIOLOGY

Berberine moderates glucose metabolism through the GnRH-GLP-1 and MAPK pathways in the intestine

(2014) Qian Zhang et al.   BMC Complementary and Alternative Medicine

PKA negatively regulates PP2Cβ to activate NF-κB-mediated inflammatory signaling

(2013) Hyo-Kyung Choi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity

(2013) Ismayil Tasdelen et al.   BIOCHEMICAL JOURNAL

PPM1B and P-IKKβ expression levels correlated inversely with rat gastrocnemius atrophy after denervation

(2012) Jian Wei et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis

(2011) Ana P. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

PPM-1, a PP2Cα/β phosphatase, Regulates Axon Termination and Synapse Formation inCaenorhabditis elegans

(2011) Erik D. Tulgren et al.   GENETICS

Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis

(2011) Xuan Xia et al.   PLoS One

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Amelioration of Insulin Resistance by Scopoletin in High-Glucose-Induced, Insulin-Resistant HepG2 Cells

(2010) W. Y. Zhang et al.   HORMONE AND METABOLIC RESEARCH

Proteomic Analysis of GLUT4 Storage Vesicles Reveals LRP1 to Be an Important Vesicle Component and Target of Insulin Signaling

(2009) Mark P. Jedrychowski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

(2009) E. Maury et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PPM1A and PPM1B act as IKKβ phosphatases to terminate TNFα-induced IKKβ-NF-κB activation

(2008) W SUN et al.   CELLULAR SIGNALLING