Autism Spectrum Disorder Associated With Gut Microbiota at Immune, Metabolomic, and Neuroactive Level

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome

(2020) Carra A. Simpson et al.   JOURNAL OF AFFECTIVE DISORDERS

Emerging evidence for gene mutations driving both brain and gut dysfunction in autism spectrum disorder

(2020) Beate Niesler et al.   MOLECULAR PSYCHIATRY

‘Autistic voices should be heard.’ Autistic adults join research teams to shift focus of studies

(2020) Emily Willingham   SCIENCE

GABA Concentration in the Left Ventral Premotor Cortex Associates With Sensory Hyper-Responsiveness in Autism Spectrum Disorders Without Intellectual Disability

(2020) Yumi Umesawa et al.   Frontiers in Neuroscience

Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism

(2019) Laurie-Anne Sapey-Triomphe et al.   Autism Research

Reprint of: Serotonin as a link between the gut-brain-microbiome axis in autism spectrum disorders

(2019) Narek Israelyan et al.   PHARMACOLOGICAL RESEARCH

Autism Spectrum Disorders and the Gut Microbiota

(2019) Antonella Fattorusso et al.   Nutrients

Antibiotic-Induced Disruption of Gut Microbiota Alters Local Metabolomes and Immune Responses

(2019) Lin Sun et al.   Frontiers in Cellular and Infection Microbiology

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

(2019) Gil Sharon et al.   CELL

Human placenta has no microbiome but can contain potential pathogens

(2019) Marcus C. de Goffau et al.   NATURE

Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder

(2019) Latifa S. Abdelli et al.   Scientific Reports

Maternal Immune Activation and Related Factors in the Risk of Offspring Psychiatric Disorders

(2019) Fiona Conway et al.   Frontiers in Psychiatry

Association Between Gut Microbiota and Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

(2019) Mingyu Xu et al.   Frontiers in Psychiatry

Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring

(2019) Silke Kreitz et al.   BRAIN BEHAVIOR AND IMMUNITY

The Microbiota-Gut-Brain Axis

(2019) John F. Cryan et al.   PHYSIOLOGICAL REVIEWS

Genetic Causes and Modifiers of Autism Spectrum Disorder

(2019) Lauren Rylaarsdam et al.   Frontiers in Cellular Neuroscience

Antibiotic effects on gut microbiota, metabolism, and beyond

(2019) Chunlong Mu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Aging progression of human gut microbiota

(2019) Congmin Xu et al.   BMC MICROBIOLOGY

Gut microbiota–brain axis in depression: The role of neuroinflammation

(2019) Anelise S. Carlessi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Propionic acid induced behavioural effects of relevance to autism spectrum disorder evaluated in the hole board test with rats

(2019) Melissa M. Meeking et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Current evidence linking diet to gut microbiota and brain development and function

(2018) Florencia Ceppa et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

Microbial taxonomic and metabolic alterations during faecal microbiota transplantation to treat Clostridium difficile infection

(2018) Lee Kellingray et al.   JOURNAL OF INFECTION

The impact of atypical sensory processing on social impairments in autism spectrum disorder

(2018) Melissa D. Thye et al.   Developmental Cognitive Neuroscience

The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis

(2018) Bruno Bonaz et al.   Frontiers in Neuroscience

The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism

(2018) Fang Liu et al.   Molecular Autism

Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome

(2017) Maria Ines Pinto-Sanchez et al.   GASTROENTEROLOGY

Feeding Problems and Nutrient Intake in Children with and without Autism: A Comparative Study

(2017) Prahbhjot Malhi et al.   INDIAN JOURNAL OF PEDIATRICS

Influence of diet on the gut microbiome and implications for human health

(2017) Rasnik K. Singh et al.   Journal of Translational Medicine

The Gut Microbiota and Autism Spectrum Disorders

(2017) Qinrui Li et al.   Frontiers in Cellular Neuroscience

The Fungal Frontier: A Comparative Analysis of Methods Used in the Study of the Human Gut Mycobiome

(2017) Chloe E. Huseyin et al.   Frontiers in Microbiology

New evidences on the altered gut microbiota in autism spectrum disorders

(2017) Francesco Strati et al.   Microbiome

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

(2017) Dae-Wook Kang et al.   Microbiome

The Human Microbiota in Health and Disease

(2017) Baohong Wang et al.   Engineering

Maternal metabolic risk factors for autism spectrum disorder-An analysis of electronic medical records and linked birth data

(2016) Natalia Connolly et al.   Autism Research

A preliminary investigation on the relationship between gut microbiota and gene expressions in peripheral mononuclear cells of infants with autism spectrum disorders

(2016) Ryo Inoue et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Leaky gut – concept or clinical entity?

(2016) Eamonn M.M. Quigley   CURRENT OPINION IN GASTROENTEROLOGY

Gut Microbiota and Obesity

(2016) Chiara Valsecchi et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Evaluation of Intestinal Function in Children With Autism and Gastrointestinal Symptoms

(2016) Rafail I. Kushak et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Breast Milk Protects Against Gastrointestinal Symptoms in Infants at High Risk for Autism During Early Development

(2016) Alexander H. Penn et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Microbiome: Bacterial broadband

(2016) Michael Eisenstein   NATURE

IBS and IBD — separate entities or on a spectrum?

(2016) Robin Spiller et al.   Nature Reviews Gastroenterology & Hepatology

The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

(2016) Raeesah Maqsood et al.   NEUROCHEMICAL RESEARCH

Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model

(2016) Neta Kratsman et al.   NEUROPHARMACOLOGY

Animal Models of Autism Spectrum Disorders and Behavioral Techniques of their Examination

(2016) S. V. Hrabovska et al.   NEUROPHYSIOLOGY

Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat

(2016) A.E. Hoban et al.   NEUROSCIENCE

The serotonin system in autism spectrum disorder: From biomarker to animal models

(2016) C.L. Muller et al.   NEUROSCIENCE

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

(2016) Moran Yassour et al.   Science Translational Medicine

Antibiotics, birth mode, and diet shape microbiome maturation during early life

(2016) Nicholas A. Bokulich et al.   Science Translational Medicine

The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation

(2016) Amy Langdon et al.   Genome Medicine

Metabiotics: One Step ahead of Probiotics; an Insight into Mechanisms Involved in Anticancerous Effect in Colorectal Cancer

(2016) Mridul Sharma et al.   Frontiers in Microbiology

Modulatory Effects of Gut Microbiota on the Central Nervous System: How Gut Could Play a Role in Neuropsychiatric Health and Diseases

(2016) Shadi S Yarandi et al.   Journal of Neurogastroenterology and Motility

Ketogenic diet modifies the gut microbiota in a murine model of autism spectrum disorder

(2016) Christopher Newell et al.   Molecular Autism

Blood–brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders

(2016) Maria Fiorentino et al.   Molecular Autism

Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers

(2016) A P Allen et al.   Translational Psychiatry

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

(2015) Maartje C P Cleophas et al.   ANNALS OF THE RHEUMATIC DISEASES

Omega-3 fatty acids in the management of autism spectrum disorders: findings from an open-label pilot study in Singapore

(2015) Y P Ooi et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook

(2015) Colleen R. Kelly et al.   GASTROENTEROLOGY

Evidence supporting an altered immune response in ASD

(2015) Jennifer Mead et al.   IMMUNOLOGY LETTERS

Autistic spectrum disorders: A review of clinical features, theories and diagnosis

(2015) Marc Fakhoury   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Gut/brain axis and the microbiota

(2015) Emeran A. Mayer et al.   JOURNAL OF CLINICAL INVESTIGATION

Collective unconscious: How gut microbes shape human behavior

(2015) Timothy G. Dinan et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

Microbiota and the gut–brain axis

(2015) John Bienenstock et al.   NUTRITION REVIEWS

Fecal microbiota transplantation as novel therapy in gastroenterology: A systematic review

(2015) Noortje G Rossen   WORLD JOURNAL OF GASTROENTEROLOGY

Explaining the Increase in the Prevalence of Autism Spectrum Disorders

(2015) Stefan N. Hansen et al.   JAMA Pediatrics

Comparison of Fecal Microbiota in Children with Autism Spectrum Disorders and Neurotypical Siblings in the Simons Simplex Collection

(2015) Joshua S. Son et al.   PLoS One

Beneficial modulation of the gut microbiota

(2014) Calum J. Walsh et al.   FEBS LETTERS

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

(2014) Edward S Chambers et al.   GUT

Research Review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis

(2014) Eileen A. Curran et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

The urinary metabolomics profile of an Italian autistic children population and their unaffected siblings

(2014) Antonio Noto et al.   Journal of Maternal-Fetal & Neonatal Medicine

The epidemiology and global burden of autism spectrum disorders

(2014) A. J. Baxter et al.   PSYCHOLOGICAL MEDICINE

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Microbiota and neurodevelopmental windows: implications for brain disorders

(2014) Yuliya E. Borre et al.   TRENDS IN MOLECULAR MEDICINE

The Impact of Diet and Lifestyle on Gut Microbiota and Human Health

(2014) Michael Conlon et al.   Nutrients

Costs of Autism Spectrum Disorders in the United Kingdom and the United States

(2014) Ariane V. S. Buescher et al.   JAMA Pediatrics

Autistic-like behavioural and neurochemical changes in a mouse model of food allergy

(2013) Caroline G.M. de Theije et al.   BEHAVIOURAL BRAIN RESEARCH

Gut microbiota of healthy Canadian infants: profiles by mode of delivery and infant diet at 4 months

(2013) M. B. Azad et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

A prospective double-blind, randomized clinical trial of levocarnitine to treat autism spectrum disorders

(2013) David A. Geier et al.   MEDICAL SCIENCE MONITOR

The BTBR Mouse Model of Autism Spectrum Disorders Has Learning and Attentional Impairments and Alterations in Acetylcholine and Kynurenic Acid in Prefrontal Cortex

(2013) Stephanie M. McTighe et al.   PLoS One

Bacterial Diversity in Meconium of Preterm Neonates and Evolution of Their Fecal Microbiota during the First Month of Life

(2013) Laura Moles et al.   PLoS One

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

(2013) Dae-Wook Kang et al.   PLoS One

Fecal Microbiota and Metabolome of Children with Autism and Pervasive Developmental Disorder Not Otherwise Specified

(2013) Maria De Angelis et al.   PLoS One

Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder

(2013) R E Frye et al.   Translational Psychiatry

Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immune-mediated inflammation

(2012) Kriston Ganguli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Gastrointestinal Dysfunction in Autism: Parental Report, Clinical Evaluation, and Associated Factors

(2012) Phillip Gorrindo et al.   Autism Research

Fecal microbiota transplantation

(2012) Olga C. Aroniadis et al.   CURRENT OPINION IN GASTROENTEROLOGY

γ-Aminobutyric acid production by culturable bacteria from the human intestine

(2012) E. Barrett et al.   JOURNAL OF APPLIED MICROBIOLOGY

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

(2012) Raymond H Thomas et al.   Journal of Neuroinflammation

Metabolic Perturbance in Autism Spectrum Disorders: A Metabolomics Study

(2012) Xue Ming et al.   JOURNAL OF PROTEOME RESEARCH

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Diversity, stability and resilience of the human gut microbiota

(2012) Catherine A. Lozupone et al.   NATURE

Microbes and the gut-brain axis

(2012) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Autism After Infection, Febrile Episodes, and Antibiotic Use During Pregnancy: An Exploratory Study

(2012) H. O. Atladottir et al.   PEDIATRICS

The human milk microbiota: Origin and potential roles in health and disease

(2012) Leónides Fernández et al.   PHARMACOLOGICAL RESEARCH

Lactobacillus reuteri Maintains a Functional Mucosal Barrier during DSS Treatment Despite Mucus Layer Dysfunction

(2012) Johan Dicksved et al.   PLoS One

Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats

(2012) Afifa Ait-Belgnaoui et al.   PSYCHONEUROENDOCRINOLOGY

Probiotic Bacteria Induce Maturation of Intestinal Claudin 3 Expression and Barrier Function

(2011) Ravi M. Patel et al.   AMERICAN JOURNAL OF PATHOLOGY

Systemic treatment with the enteric bacterial fermentation product, propionic acid, produces both conditioned taste avoidance and conditioned place avoidance in rats

(2011) Klaus-Peter Ossenkopp et al.   BEHAVIOURAL BRAIN RESEARCH

Gastrointestinal flora and gastrointestinal status in children with autism – comparisons to typical children and correlation with autism severity

(2011) James B Adams et al.   BMC GASTROENTEROLOGY

The role of immune dysfunction in the pathophysiology of autism

(2011) Charity Onore et al.   BRAIN BEHAVIOR AND IMMUNITY

Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

(2011) Caroline G.M. de Theije et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives

(2011) M. Joossens et al.   GUT

The Prevalence of Gastrointestinal Problems in Children Across the United States With Autism Spectrum Disorders From Families With Multiple Affected Members

(2011) Lulu W. Wang et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures

(2011) D A Rossignol et al.   MOLECULAR PSYCHIATRY

Gut feelings: the emerging biology of gut–brain communication

(2011) Emeran A. Mayer   NATURE REVIEWS NEUROSCIENCE

The level of arabinitol in autistic children after probiotic therapy

(2011) Joanna Kałużna-Czaplińska et al.   NUTRITION

Alteration of Plasma Glutamate and Glutamine Levels in Children with High-Functioning Autism

(2011) Chie Shimmura et al.   PLoS One

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal gut microbiota modulates brain development and behavior

(2011) R. D. Heijtz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

(2010) Jurgen Karczewski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder

(2010) Derrick F. MacFabe et al.   BEHAVIOURAL BRAIN RESEARCH

Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms

(2010) Sa'ad H. Al-Lahham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome

(2010) Paul Ashwood et al.   BRAIN BEHAVIOR AND IMMUNITY

Assessment of psychotropic-like properties of a probiotic formulation ( Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects

(2010) Michaël Messaoudi et al.   BRITISH JOURNAL OF NUTRITION

Bacterial infection causes stress-induced memory dysfunction in mice

(2010) M. G. Gareau et al.   GUT

Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First-degree Relatives

(2010) Laura de Magistris et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Food Selectivity in Children with Autism Spectrum Disorders and Typically Developing Children

(2010) Linda G. Bandini et al.   JOURNAL OF PEDIATRICS

Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens

(2010) Sarah Lebeer et al.   NATURE REVIEWS MICROBIOLOGY

Low-grade endotoxemia in patients with severe autism

(2010) Enzo Emanuele et al.   NEUROSCIENCE LETTERS

Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite ofClostridiaspp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia

(2010) William Shaw   NUTRITIONAL NEUROSCIENCE

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome

(2009) A Venket Rao et al.   Gut Pathogens

The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat

(2008) Lieve Desbonnet et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Cellulose modulates biofilm formation by counteracting curli-mediated colonization of solid surfaces in Escherichia coli

(2008) L. Gualdi et al.   MICROBIOLOGY-SGM

Immune-To-Brain Signaling: How Important are the Blood–Brain Barrier-independent Pathways?

(2008) Ning Quan   MOLECULAR NEUROBIOLOGY

Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: Implications for an animal model of autism

(2008) Sandy R. Shultz et al.   NEUROPHARMACOLOGY

Microbial Prevalence, Diversity and Abundance in Amniotic Fluid During Preterm Labor: A Molecular and Culture-Based Investigation

(2008) Daniel B. DiGiulio et al.   PLoS One

Is meconium from healthy newborns actually sterile?

(2008) Esther Jiménez et al.   RESEARCH IN MICROBIOLOGY