Nanotechnology-Assisted Isolation and Analysis of Circulating Tumor Cells on Microfluidic Devices

Hierarchical Spiky Microstraws‐Integrated Microfluidic Device for Efficient Capture and In Situ Manipulation of Cancer Cells

(2019) Gen He et al.   ADVANCED FUNCTIONAL MATERIALS

Deep learning for cellular image analysis

(2019) Erick Moen et al.   NATURE METHODS

Cancer treatment and survivorship statistics, 2019

(2019) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells

(2019) Yu-Heng Cheng et al.   Nature Communications

Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells

(2019) Jiantong Dong et al.   Science Advances

Acoustofluidic separation of cells and particles

(2019) Mengxi Wu et al.   Microsystems & Nanoengineering

Nanostructured Substrates for Detection and Characterization of Circulating Rare Cells: From Materials Research to Clinical Applications

(2019) Jiantong Dong et al.   ADVANCED MATERIALS

Multifunctional Branched Nanostraw-Electroporation Platform for Intracellular Regulation and Monitoring of Circulating Tumor Cells

(2019) Gen He et al.   NANO LETTERS

Efficient Capture and High Activity Release of Circulating Tumor Cells by Using TiO2 Nanorod Arrays Coated with Soluble MnO2 Nanoparticles

(2018) R. Li et al.   ACS Applied Materials & Interfaces

Folic Acid-Functionalized Hybrid Photonic Barcodes for Capture and Release of Circulating Tumor Cells

(2018) Chengxin Luan et al.   ACS Applied Materials & Interfaces

Size-based separation methods of circulating tumor cells

(2018) Si-Jie Hao et al.   ADVANCED DRUG DELIVERY REVIEWS

Microfluidic technologies for circulating tumor cell isolation

(2018) Hyungseok Cho et al.   ANALYST

Utility of cell-free nucleic acid and circulating tumor cell analyses in prostate cancer

(2018) Guru Sonpavde et al.   ASIAN JOURNAL OF ANDROLOGY

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images

(2018) Eric M. Christiansen et al.   CELL

Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma

(2018) Wenting Jiang et al.   International Journal of Nanomedicine

Combining Multiplex SERS Nanovectors and Multivariate Analysis for In Situ Profiling of Circulating Tumor Cell Phenotype Using a Microfluidic Chip

(2018) Yizhi Zhang et al.   Small

Recent advances in single cell manipulation and biochemical analysis on microfluidics

(2018) Dan Gao et al.   ANALYST

Chip-Assisted Single-Cell Biomarker Profiling of Heterogeneous Circulating Tumor Cells Using Multifunctional Nanospheres

(2018) Ling-Ling Wu et al.   ANALYTICAL CHEMISTRY

Standing Surface Acoustic Wave (SSAW)-Based Fluorescence-Activated Cell Sorter

(2018) Liqiang Ren et al.   Small

Synthesizing Living Tissues with Microfluidics

(2018) Wenfu Zheng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells

(2018) Yanling Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Capture and biological release of circulating tumor cells in pancreatic cancer based on peptide-functionalized silicon nanowire substrate

(2018) Qinglin Shen et al.   International Journal of Nanomedicine

Detection of CTC Clusters and a Dedifferentiated RNA-Expression Survival Signature in Prostate Cancer

(2018) Molly Kozminsky et al.   Advanced Science

Enhanced Isolation and Release of Circulating Tumor Cells Using Nanoparticle Binding and Ligand Exchange in a Microfluidic Chip

(2017) Myoung-Hwan Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Magnetic particles assisted capture and release of rare circulating tumor cells using wavy-herringbone structured microfluidic devices

(2017) Wentao Shi et al.   LAB ON A CHIP

Open channel deterministic lateral displacement for particle and cell sorting

(2017) Trung S. H. Tran et al.   LAB ON A CHIP

An integrated microfluidic chip for one-step isolation of circulating tumor cells

(2017) Tae Yoon Lee et al.   SENSORS AND ACTUATORS B-CHEMICAL

Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection

(2017) Mo-Yuan Shen et al.   Advanced Healthcare Materials

Hyaluronic acid-functionalized electrospun PLGA nanofibers embedded in a microfluidic chip for cancer cell capture and culture

(2017) Gangwei Xu et al.   Biomaterials Science

Degradable Zinc-Phosphate-Based Hierarchical Nanosubstrates for Capture and Release of Circulating Tumor Cells

(2016) Shan Guo et al.   ACS Applied Materials & Interfaces

Near-Infrared Light-Responsive Hydrogel for Specific Recognition and Photothermal Site-Release of Circulating Tumor Cells

(2016) Song-Wei Lv et al.   ACS Nano

FAST: Size-Selective, Clog-Free Isolation of Rare Cancer Cells from Whole Blood at a Liquid–Liquid Interface

(2016) Tae-Hyeong Kim et al.   ANALYTICAL CHEMISTRY

Profiling Functional and Biochemical Phenotypes of Circulating Tumor Cells Using a Two-Dimensional Sorting Device

(2016) Mahla Poudineh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-throughput and clogging-free microfluidic filtration platform for on-chip cell separation from undiluted whole blood

(2016) Yinuo Cheng et al.   Biomicrofluidics

Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer

(2016) Colin M. Court et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

(2016) Mahla Poudineh et al.   Nature Nanotechnology

Molecular profiling of single circulating tumor cells from lung cancer patients

(2016) Seung-min Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Purification and Release of Circulating Tumor Cells by Synergistic Effect of Biomarker and SiO2@Gel-Microbead-Based Size Difference Amplification

(2016) Qinqin Huang et al.   Advanced Healthcare Materials

Capture and Release of Cancer Cells by Combining On-Chip Purification and Off-Chip Enzymatic Treatment

(2015) Xiaolei Yu et al.   ACS Applied Materials & Interfaces

Single-Cell Codetection of Metabolic Activity, Intracellular Functional Proteins, and Genetic Mutations from Rare Circulating Tumor Cells

(2015) Yu Zhang et al.   ANALYTICAL CHEMISTRY

Capture and release of cancer cells using electrospun etchable MnO2 nanofibers integrated in microchannels

(2015) Hui-qin Liu et al.   APPLIED PHYSICS LETTERS

Two-stage microfluidic chip for selective isolation of circulating tumor cells (CTCs)

(2015) Kyung-A Hyun et al.   BIOSENSORS & BIOELECTRONICS

Subclassification of prostate cancer circulating tumor cells by nuclear size reveals very small nuclear circulating tumor cells in patients with visceral metastases

(2015) Jie-Fu Chen et al.   CANCER

Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

(2015) C. Wyatt Shields IV et al.   LAB ON A CHIP

Velocity valleys enable efficient capture and spatial sorting of nanoparticle-bound cancer cells

(2015) Justin D. Besant et al.   Nanoscale

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

(2015) A Fatih Sarioglu et al.   NATURE METHODS

Photoresponsive immunomagnetic nanocarrier for capture and release of rare circulating tumor cells

(2015) Song-Wei Lv et al.   Chemical Science

A comparison of isolated circulating tumor cells and tissue biopsies using whole-genome sequencing in prostate cancer

(2015) Runze Jiang et al.   Oncotarget

Integrated 3D conducting polymer-based bioelectronics for capture and release of circulating tumor cells

(2015) Yu-Sheng Hsiao et al.   Journal of Materials Chemistry B

Nanostructure Embedded Microchips for Detection, Isolation, and Characterization of Circulating Tumor Cells

(2014) Millicent Lin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Programming Thermoresponsiveness of NanoVelcro Substrates Enables Effective Purification of Circulating Tumor Cells in Lung Cancer Patients

(2014) Zunfu Ke et al.   ACS Nano

Emerging Role of Nanomaterials in Circulating Tumor Cell Isolation and Analysis

(2014) Hyeun Joong Yoon et al.   ACS Nano

Engineered Decomposable Multifunctional Nanobioprobes for Capture and Release of Rare Cancer Cells

(2014) Min Xie et al.   ANALYTICAL CHEMISTRY

Nanoparticle-Mediated Binning and Profiling of Heterogeneous Circulating Tumor Cell Subpopulations

(2014) Reza M. Mohamadi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Electroactive Biotin-Doped Polypyrrole Substrate That Immobilizes and Releases EpCAM-Positive Cancer Cells

(2014) SeungHyun Jeon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor cell characterization and classification based on cellular specific membrane capacitance and cytoplasm conductivity

(2014) Y. Zhao et al.   BIOSENSORS & BIOELECTRONICS

Three-dimensional nano-biointerface as a new platform for guiding cell fate

(2014) Xueli Liu et al.   CHEMICAL SOCIETY REVIEWS

Functional analysis of single cells identifies a rare subset of circulating tumor cells with malignant traits

(2014) Xiaosai Yao et al.   Integrative Biology

High-throughput rare cell separation from blood samples using steric hindrance and inertial microfluidics

(2014) Shaofei Shen et al.   LAB ON A CHIP

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Detection of Live Circulating Tumor Cells by a Class of Near-Infrared Heptamethine Carbocyanine Dyes in Patients with Localized and Metastatic Prostate Cancer

(2014) Chen Shao et al.   PLoS One

Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

(2014) M. Yu et al.   SCIENCE

Versatile Immunomagnetic Nanocarrier Platform for Capturing Cancer Cells

(2013) Chun-Hsien Wu et al.   ACS Nano

Specific Capture and Release of Circulating Tumor Cells Using Aptamer-Modified Nanosubstrates

(2013) Qinglin Shen et al.   ADVANCED MATERIALS

Polymer Nanofiber-Embedded Microchips for Detection, Isolation, and Molecular Analysis of Single Circulating Melanoma Cells

(2013) Shuang Hou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Isolation and Accurate In Situ Analysis of Circulating Tumor Cells Using Detachable Beads and a High-Pore-Density Filter

(2013) Hun Joo Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell detachment: Post-isolation challenges

(2013) Qin Zheng et al.   BIOTECHNOLOGY ADVANCES

Towards a personalized breast cancer treatment approach guided by circulating tumor cell (CTC) characteristics

(2013) W. Onstenk et al.   CANCER TREATMENT REVIEWS

Advances of lab-on-a-chip in isolation, detection and post-processing of circulating tumour cells

(2013) Ling Yu et al.   LAB ON A CHIP

Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells

(2013) Majid Ebrahimi Warkiani et al.   LAB ON A CHIP

Gelatin–mesoporous silica nanoparticles as matrix metalloproteinases-degradable drug delivery systems in vivo

(2013) Jun-Hua Xu et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Nanostructured substrates for isolation of circulating tumor cells

(2013) Lixue Wang et al.   Nano Today

Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets

(2013) Hyeun Joong Yoon et al.   Nature Nanotechnology

Circulating Tumor Cells Count and Morphological Features in Breast, Colorectal and Prostate Cancer

(2013) Sjoerd T. Ligthart et al.   PLoS One

Filter Characteristics Influencing Circulating Tumor Cell Enrichment from Whole Blood

(2013) Frank A. W. Coumans et al.   PLoS One

Advances in three-dimensional nanofibrous macrostructures via electrospinning

(2013) B. Sun et al.   PROGRESS IN POLYMER SCIENCE

Circulating Tumor Cells

(2013) V. Plaks et al.   SCIENCE

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

Isolation and retrieval of circulating tumor cells using centrifugal forces

(2013) Han Wei Hou et al.   Scientific Reports

Thin film hydrophilic electroactive polymer coatings for bioelectrodes

(2013) Sungchul Baek et al.   Journal of Materials Chemistry B

Hydrophobic Interaction-Mediated Capture and Release of Cancer Cells on Thermoresponsive Nanostructured Surfaces

(2012) Hongliang Liu et al.   ADVANCED MATERIALS

Biopolymer System for Cell Recovery from Microfluidic Cell Capture Devices

(2012) Ajay M. Shah et al.   ANALYTICAL CHEMISTRY

Immunomagnetic nanoscreening of circulating tumor cells with a motion controlled microfluidic system

(2012) Yu-yen Huang et al.   BIOMEDICAL MICRODEVICES

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm

(2012) Jianbin Wang et al.   CELL

Changes in Electric Properties of Human Breast Cancer Cells

(2012) Izabela Dobrzyńska et al.   JOURNAL OF MEMBRANE BIOLOGY

Specific capture and temperature-mediated release of cells in an aptamer-based microfluidic device

(2012) Jing Zhu et al.   LAB ON A CHIP

Microfluidic approaches for cancer cell detection, characterization, and separation

(2012) Jian Chen et al.   LAB ON A CHIP

Cell adhesion and migration on nanopatterned substrates and their effects on cell-capture yield

(2012) Dong-Joo Kim et al.   NANOTECHNOLOGY

Cell Stiffness Is a Biomarker of the Metastatic Potential of Ovarian Cancer Cells

(2012) Wenwei Xu et al.   PLoS One

Statistical analysis of immuno-functionalized tumor-cell behaviors on nanopatterned substrates

(2012) Dong-Joo Kim et al.   Nanoscale Research Letters

Sensitivity Improved Surface Plasmon Resonance Biosensor for Cancer Biomarker Detection Based on Plasmonic Enhancement

(2011) Wing-Cheung Law et al.   ACS Nano

High-Throughput Selection, Enumeration, Electrokinetic Manipulation, and Molecular Profiling of Low-Abundance Circulating Tumor Cells Using a Microfluidic System

(2011) Udara Dharmasiri et al.   ANALYTICAL CHEMISTRY

Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

(2011) Shutao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches

(2011) Matthew G. Krebs et al.   Journal of Thoracic Oncology

Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)

(2011) Hui-Sung Moon et al.   LAB ON A CHIP

Microchip-based immunomagnetic detection of circulating tumor cells

(2011) Kazunori Hoshino et al.   LAB ON A CHIP

Circulating Tumor Cells from Patients with Advanced Prostate and Breast Cancer Display Both Epithelial and Mesenchymal Markers

(2011) A. J. Armstrong et al.   MOLECULAR CANCER RESEARCH

Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines

(2010) Stacy R. Millon et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

Detachment of captured cancer cells under flow acceleration in a bio-functionalized microchannel

(2009) Luthur Siu Lun Cheung et al.   LAB ON A CHIP

Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells

(2009) Farhan Chowdhury et al.   NATURE MATERIALS

Circulating Tumor Cells: Evolving Evidence and Future Challenges

(2009) E. Dotan et al.   ONCOLOGIST

Cell Adhesion and Spreading Behavior on Vertically Aligned Silicon Nanowire Arrays

(2008) Suijian Qi et al.   ACS Applied Materials & Interfaces

Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells

(2008) Anieta M. Sieuwerts et al.   JNCI-Journal of the National Cancer Institute