Alpha lipoic acid antagonizes cytotoxicity of cobalt nanoparticles by inhibiting ferroptosis-like cell death

Cobalt nanoparticles trigger ferroptosis‐like cell death (oxytosis) in neuronal cells: Potential implications for neurodegenerative disease

(2020) Govind Gupta et al.   FASEB JOURNAL

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

α-Lipoic Acid Reduces Iron-induced Toxicity and Oxidative Stress in a Model of Iron Overload

(2019) Giuseppina Camiolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Therapeutic applications of selenium nanoparticles

(2019) Amit Khurana et al.   BIOMEDICINE & PHARMACOTHERAPY

The role of Ca 2+ in cell death caused by oxidative glutamate toxicity and ferroptosis

(2018) Pamela Maher et al.   CELL CALCIUM

α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice

(2018) Yan-Hui Zhang et al.   Redox Biology

Biochemical and clinical relevance of alpha lipoic acid: antioxidant and anti-inflammatory activity, molecular pathways and therapeutic potential

(2017) Daniele Tibullo et al.   INFLAMMATION RESEARCH

Melatonin counteracts cobalt nanoparticle-induced cytotoxicity and genotoxicity by deactivating reactive oxygen species-dependent mechanisms in the NRK cell line

(2017) Yake Liu et al.   Molecular Medicine Reports

Can zinc protect cells from the cytotoxic effects of cobalt ions and nanoparticles derived from metal-on-metal joint arthroplasties?

(2017) Y. Liu et al.   Bone & Joint Research

The Roles of NRF2 in Modulating Cellular Iron Homeostasis

(2017) Michael John Kerins et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy mediated TiAl 6 V 4 particle-induced peri-implant osteolysis by promoting expression of TNF-α

(2016) Naicheng Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

l-Ascorbic Acid Protected Against Extrinsic and Intrinsic Apoptosis Induced by Cobalt Nanoparticles Through ROS Attenuation

(2016) Yake Liu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Cobalt iron oxide nanoparticles induce cytotoxicity and regulate the apoptotic genes through ROS in human liver cells (HepG2)

(2016) Maqusood Ahamed et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Co–Cr dental alloys induces cytotoxicity and inflammatory responses via activation of Nrf2/antioxidant signaling pathways in human gingival fibroblasts and osteoblasts

(2016) Eun-Cheol Kim et al.   DENTAL MATERIALS

Interplay between the chalcone cardamonin and selenium in the biosynthesis of Nrf2-regulated antioxidant enzymes in intestinal Caco-2 cells

(2016) Silke De Spirt et al.   FREE RADICAL BIOLOGY AND MEDICINE

Does therapeutic plasma exchange have a role in the treatment of prosthetic hip-associated cobalt toxicity? A case report and literature review

(2016) Michelle L. Grant et al.   TRANSFUSION

Systemic cobalt toxicity from total hip arthroplasties

(2016) M. G. Zywiel et al.   Bone & Joint Journal

Cytotoxicity and genotoxicity in liver cells induced by cobalt nanoparticles and ions

(2016) Y. K. Liu et al.   Bone & Joint Research

Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis

(2015) Guoyin Liu et al.   CELL AND TISSUE RESEARCH

Importance of the HIF pathway in cobalt nanoparticle-induced cytotoxicity and inflammation in human macrophages

(2015) Agata Nyga et al.   Nanotoxicology

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice

(2015) Yogesh Saini et al.   PLoS One

A Systematic Review of Systemic Cobaltism After Wear or Corrosion of Chrome-Cobalt Hip Implants

(2015) Bradford D. Gessner et al.   Journal of Patient Safety

Molecular analysis of chromium and cobalt-related toxicity

(2014) Brian Scharf et al.   Scientific Reports

Systemic Disease After Hip Replacement: Aeromedical Implications of Arthroprosthetic Cobaltism

(2013) John G. Sotos et al.   AVIATION SPACE AND ENVIRONMENTAL MEDICINE

Particle-induced osteolysis mediated by endoplasmic reticulum stress in prosthesis loosening

(2013) Rui Wang et al.   BIOMATERIALS

Consequences of exposure to peri-articular injections of micro- and nano-particulate cobalt–chromium alloy

(2013) Christopher Brown et al.   BIOMATERIALS

Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity

(2013) Vijay Krishna Raghunathan et al.   BIOMATERIALS

A review of the health hazards posed by cobalt

(2013) Dennis J. Paustenbach et al.   CRITICAL REVIEWS IN TOXICOLOGY

Apoptosis induced by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS generation through both extrinsic and intrinsic apoptosis pathways

(2013) JINSHUN ZHAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cytotoxicity and morphological transforming potential of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts: anin vitromodel

(2013) Enrico Sabbioni et al.   Nanotoxicology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Severe cobalt intoxication following hip replacement revision: Clinical features and outcome

(2012) Daniela Pelclova et al.   CLINICAL TOXICOLOGY

Cobalt metabolism and toxicology—A brief update

(2012) Lars Ole Simonsen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cobalt, chromium and molybdenum ions kinetics in the human body: data gained from a total hip replacement with massive third body wear of the head and neuropathy by cobalt intoxication

(2011) U. E. Pazzaglia et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Cementless Metal-on-Metal Versus Ceramic-on-Polyethylene Hip Arthroplasty in Patients Less Than Fifty Years of Age

(2011) Henri Migaud et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Arthroprosthetic Cobaltism: Neurological and Cardiac Manifestations in Two Patients with Metal-on-Metal Arthroplasty

(2010) Stephen S Tower   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

Polyneuropathy caused by cobalt-chromium metallosis after total hip replacement

(2010) Tokuhei Ikeda et al.   MUSCLE & NERVE

Dose-dependent cytotoxicity of clinically relevant cobalt nanoparticles and ions on macrophagesin vitro

(2009) Young-Min Kwon et al.   Biomedical Materials

Rapid DNA Double-Strand Breaks Resulting from Processing of Cr-DNA Cross-Links by Both MutS Dimers

(2009) M. F. Reynolds et al.   CANCER RESEARCH

Comparative genotoxicity of cobalt nanoparticles and ions on human peripheral leukocytes in vitro

(2008) R. Colognato et al.   MUTAGENESIS