Regulator of G‐Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia

Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice

(2018) Yukio Hiroi et al.   CIRCULATION JOURNAL

Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5

(2018) Caroline Arnold et al.   FASEB JOURNAL

Structure and dynamics of GPCR signaling complexes

(2018) Daniel Hilger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and dynamics of GPCR signaling complexes

(2018) Daniel Hilger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss of Regulator of G-Protein Signaling 5 Leads to Neurovascular Protection in Stroke

(2018) Ilknur Özen et al.   STROKE

ROCK as a therapeutic target for ischemic stroke

(2017) Nikola Sladojevic et al.   Expert Review of Neurotherapeutics

Regulator of G protein signaling 5 (RGS5) inhibits sonic hedgehog function in mouse cortical neurons

(2017) Chuanliang Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

ROCK as a therapeutic target for ischemic stroke

(2017) Nikola Sladojevic et al.   Expert Review of Neurotherapeutics

Early oxygen therapy does not protect the brain from vasogenic edema following acute ischemic stroke in adult male rats

(2017) Elmira Pasban et al.   Scientific Reports

Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis

(2016) Richard Macrez et al.   BRAIN

Blood Pressure in Acute Ischemic Stroke

(2016) Michael McManus et al.   Journal of Clinical Neurology

Glutamate Induces Blood–Brain Barrier Permeability through Activation of N -Methyl-D-Aspartate Receptors

(2016) Kristiana Xhima et al.   JOURNAL OF NEUROSCIENCE

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

(2016) Meng Tian et al.   Scientific Reports

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

Association of regulator of G protein signaling (RGS5) gene variants and essential hypertension in Mongolian and Han populations

(2015) P.Y. Chang et al.   GENETICS AND MOLECULAR RESEARCH

Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke

(2015) Qi-jin Yu et al.   Neural Regeneration Research

Regulator of G protein signaling 5 is a determinant of gestational hypertension and preeclampsia

(2015) Vasyl Holobotovskyy et al.   Science Translational Medicine

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Neurons Limit Angiogenesis by Titrating VEGF in Retina

(2014) Keisuke Okabe et al.   CELL

Recent Progress in Understanding Subtype Specific Regulation of NMDA Receptors by G Protein Coupled Receptors (GPCRs)

(2014) Kai Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabotropic Glutamate Receptor-1 as a Novel Target for the Antiangiogenic Treatment of Breast Cancer

(2014) Cecilia L. Speyer et al.   PLoS One

Regulator of G-Protein Signaling 5 Controls Blood Pressure Homeostasis and Vessel Wall Remodeling

(2013) Vasyl Holobotovskyy et al.   CIRCULATION RESEARCH

Glutamate, Glutamate Receptors, and Downstream Signaling Pathways

(2013) Stacey S. Willard et al.   International Journal of Biological Sciences

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Increased Rho kinase activity in congestive heart failure

(2012) Ming Dong et al.   EUROPEAN JOURNAL OF HEART FAILURE

Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor’s proangiogenic microenvironment

(2011) Antonietta Silini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Association of ATP1B1, RGS5 and SELE polymorphisms with hypertension and blood pressure in African–Americans

(2011) Mezbah U. Faruque et al.   JOURNAL OF HYPERTENSION

Modulation of the "blood-tumor" barrier improves immunotherapy

(2010) Mitali Manzur et al.   CELL CYCLE

Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RGS5, a Hypoxia-inducible Apoptotic Stimulator in Endothelial Cells

(2009) Yi Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Newborn- and Adult-Derived Brain Microvascular Endothelial Cells Show Age-Related Differences in Phenotype and Glutamate-Evoked Protease Release

(2009) Hélène Legros et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Generation and Characterization of rgs5 Mutant Mice

(2008) M. H. Nisancioglu et al.   MOLECULAR AND CELLULAR BIOLOGY

Rgs5 Targeting Leads to Chronic Low Blood Pressure and a Lean Body Habitus

(2008) H. Cho et al.   MOLECULAR AND CELLULAR BIOLOGY

Vascular normalization in Rgs5-deficient tumours promotes immune destruction

(2008) Juliana Hamzah et al.   NATURE

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models

(2007) Atsuyuki Kohara et al.   BRAIN RESEARCH