m6A RNA methylation impacts fate choices during skin morphogenesis

Cross talk between RNA N6‐methyladenosine methyltransferase‐like 3 and miR‐186 regulates hepatoblastoma progression through Wnt/β‐catenin signalling pathway

(2020) Xichun Cui et al.   CELL PROLIFERATION

YTHDF 1‐mediated translation amplifies Wnt‐driven intestinal stemness

(2020) Bing Han et al.   EMBO REPORTS

m6A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling

(2020) Bo Tang et al.   Molecular Cancer

Liquid-liquid phase separation drives skin barrier formation

(2020) Felipe Garcia Quiroz et al.   SCIENCE

Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development

(2020) Irina Matos et al.   eLife

A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA

(2020) Sara Zaccara et al.   CELL

RNA modifications regulating cell fate in cancer

(2019) Sylvain Delaunay et al.   NATURE CELL BIOLOGY

Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation

(2019) Heather Lee et al.   NATURE CELL BIOLOGY

YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activity in Human Colorectal Carcinoma

(2019) Yang Bai et al.   Frontiers in Oncology

Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster

(2019) Manuela Piazzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

c-Myc steers translation in lymphoma

(2019) Marie Cargnello et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development

(2019) Jeongwoo Kwon et al.   Scientific Reports

Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer

(2019) Cheng Zhang et al.   Cancer Medicine

The m6A methyltransferase METTL3 promotes osteosarcoma progression by regulating the m6A level of LEF1

(2019) Wujun Miao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin

(2019) Natalia A. Veniaminova et al.   DEVELOPMENTAL CELL

m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment

(2019) Yuanming Cheng et al.   Cell Reports

Stem cell–driven lymphatic remodeling coordinates tissue regeneration

(2019) Shiri Gur-Cohen et al.   SCIENCE

The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells

(2019) Dongling Zou et al.   Cancer Cell International

m6A mRNA methylation regulates CTNNB1 to promote the proliferation of hepatoblastoma

(2019) Li Liu et al.   Molecular Cancer

Integrative network analysis identifies cell-specific trans regulators of m6A

(2019) Sanqi An et al.   NUCLEIC ACIDS RESEARCH

Dermal sheath contraction powers stem cell niche relocation during hair cycle regression

(2019) Nicholas Heitman et al.   SCIENCE

Mettl3–Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells

(2018) Qi Jason Yao et al.   CELL RESEARCH

Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression

(2018) Rene C. Adam et al.   Cell Stem Cell

METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m 6 A Modification

(2018) Hengyou Weng et al.   Cell Stem Cell

An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

(2018) Kifayathullah Liakath-Ali et al.   NATURE

Interactions, localization, and phosphorylation of the m 6 A generating METTL3–METTL14–WTAP complex

(2018) Eva Schöller et al.   RNA

METTL3-mediated N6-methyladenosine mRNA modification enhances long-term memory consolidation

(2018) Zeyu Zhang et al.   CELL RESEARCH

Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent

(2018) Ka-Wai Mok et al.   DEVELOPMENTAL CELL

A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy

(2018) Adriana Sánchez-Danés et al.   NATURE

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

(2018) Hailing Shi et al.   NATURE

Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis

(2018) Yunshu Wu et al.   Nature Communications

Holocrine Secretion of Sebum Is a Unique DNase2-Dependent Mode of Programmed Cell Death

(2017) Heinz Fischer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The RNA m 6 A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

(2017) Ivayla Ivanova et al.   MOLECULAR CELL

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

(2017) Hua-Bing Li et al.   NATURE

Translation from unconventional 5′ start sites drives tumour initiation

(2017) Ataman Sendoel et al.   NATURE

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Coupling organelle inheritance with mitosis to balance growth and differentiation

(2017) Amma Asare et al.   SCIENCE

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation

(2016) Tamara Ouspenskaia et al.   CELL

Posttranscriptional m 6 A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

(2016) Edward M. Kennedy et al.   Cell Host & Microbe

Phosphorylation of eIF2α Is a Translational Control Mechanism Regulating Muscle Stem Cell Quiescence and Self-Renewal

(2016) Victoria Zismanov et al.   Cell Stem Cell

Early epithelial signaling center governs tooth budding morphogenesis

(2016) Laura Ahtiainen et al.   JOURNAL OF CELL BIOLOGY

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis

(2016) Anja Fleger-Weckmann et al.   MATRIX BIOLOGY

Stem cell function and stress response are controlled by protein synthesis

(2016) Sandra Blanco et al.   NATURE

m6A RNA methylation promotes XIST-mediated transcriptional repression

(2016) Deepak P. Patil et al.   NATURE

Translation from the 5' untranslated region shapes the integrated stress response

(2016) S. R. Starck et al.   SCIENCE

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

(2015) Bastian Linder et al.   NATURE METHODS

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle

(2015) Zijian Xu et al.   eLife

Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis

(2014) Michael Buszczak et al.   CELL

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

(2014) Pedro J. Batista et al.   Cell Stem Cell

Haematopoietic stem cells require a highly regulated protein synthesis rate

(2014) Robert A. J. Signer et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

(2013) Denny L. Cottle et al.   Cell Reports

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop

(2012) W.-M. Woo et al.   GENES & DEVELOPMENT

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

MicroRNAs and their roles in mammalian stem cells

(2011) R. Yi et al.   JOURNAL OF CELL SCIENCE

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

A novel synthesis and detection method for cap-associated adenosine modifications in mouse mRNA

(2011) Susanne Kruse et al.   Scientific Reports

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

(2011) Sandra Blanco et al.   PLoS Genetics

p120ctn and P-Cadherin but Not E-Cadherin Regulate Cell Motility and Invasion of DU145 Prostate Cancer Cells

(2010) Sandra Kümper et al.   PLoS One

Epidermal patterning and induction of different hair types during mouse embryonic development

(2009) Olivier Duverger et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

(2009) Melanie A. Berta et al.   EMBO Molecular Medicine

A Hierarchical Network Controls Protein Translation during Murine Embryonic Stem Cell Self-Renewal and Differentiation

(2008) Prabha Sampath et al.   Cell Stem Cell

Epidermal Notch signalling: differentiation, cancer and adhesion

(2008) Fiona M Watt et al.   CURRENT OPINION IN CELL BIOLOGY

Multiple Roles of Notch Signaling in the Regulation of Epidermal Development

(2008) Mariko Moriyama et al.   DEVELOPMENTAL CELL

Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

(2008) J. Gao et al.   GENES & DEVELOPMENT

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE