Schisandra Inhibit Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rats via Suppressing M2 Macrophage Polarization

Comparative effectiveness of 3 Traditional Chinese Medicine treatment methods for idiopathic pulmonary fibrosis

(2019) Li-Jian Pang et al.   MEDICINE

Protective Effect of the Traditional Chinese Patent Medicine Qing‐Xuan Granule against Bleomycin‐Induced Pulmonary Fibrosis in mice

(2019) Bei Liu et al.   CHEMISTRY & BIODIVERSITY

Asiatic acid inhibits cardiac fibrosis throughNrf2/HO-1 and TGF-β1/Smads signaling pathways in spontaneous hypertension rats

(2019) Zhe Meng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Total extract of Xin Jia Xuan Bai Cheng Qi decoction inhibits pulmonary fibrosis via the TGF-β/Smad signaling pathways in vivo and in vitro

(2019) Hui Qin et al.   Drug Design Development and Therapy

A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo

(2018) Lidia Jiménez-García et al.   BIOCHEMICAL PHARMACOLOGY

New insights into TGF-β/Smad signaling in tissue fibrosis

(2018) He-He Hu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Rubus idaeus L. (red raspberry) blocks UVB-induced MMP production and promotes type I procollagen synthesis via inhibition of MAPK/AP-1, NF-κβ and stimulation of TGF-β/Smad, Nrf2 in normal human dermal fibroblasts

(2018) Wei Gao et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Combination of Salvia miltiorrhiza and ligustrazine attenuates bleomycin-induced pulmonary fibrosis in rats via modulating TNF-α and TGF-β

(2018) Chengliang Huang et al.   Chinese Medicine

Effect of Fructus schisandrae syrup on bronchial asthma mice model

(2018) Mengfan Peng et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Significance of M2 macrophage in tubulointerstitial disease secondary to primary Sjogren's disease

(2018) Jun Li et al.   RENAL FAILURE

Regulatory effects of dermal papillary pluripotent stem cells on polarization of macrophages from M1 to M2 phenotype in vitro

(2018) Meiying Li et al.   TRANSPLANT IMMUNOLOGY

Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer

(2018) Marta Helena Kubala et al.   Cell Reports

Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway

(2017) Yan Zhou et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Ginsenoside Rg1 Ameliorates Cigarette Smoke-Induced Airway Fibrosis by Suppressing the TGF-β1/Smad Pathway In Vivo and In Vitro

(2017) Sibin Guan et al.   Biomed Research International

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition

(2017) Xiao-Ming Zhou et al.   Frontiers in Pharmacology

Idiopathic pulmonary fibrosis

(2017) Fernando J. Martinez et al.   Nature Reviews Disease Primers

Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway

(2016) Yu Ji et al.   ACTA PHARMACOLOGICA SINICA

TGF-β/SMAD Pathway and Its Regulation in Hepatic Fibrosis

(2016) Fengyun Xu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro

(2016) Kang Sun et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats

(2016) Shan-Shan Rao et al.   Journal of Thoracic Disease

Idiopathic pulmonary fibrosis: An update

(2015) Paolo Spagnolo et al.   ANNALS OF MEDICINE

miR-1343 attenuates pathways of fibrosis by targeting the TGF-  receptors

(2015) L. R. Stolzenburg et al.   BIOCHEMICAL JOURNAL

IRAK-M Promotes Alternative Macrophage Activation and Fibroproliferation in Bleomycin-Induced Lung Injury

(2015) Megan N. Ballinger et al.   JOURNAL OF IMMUNOLOGY

A comparative study between Wuweizi seed and its post-ethanol extraction residue in normal and hypercholesterolemic mice

(2015) Zhu-Sheng Chu et al.   Lipids in Health and Disease

Forced Vital Capacity in Idiopathic Pulmonary Fibrosis — FDA Review of Pirfenidone and Nintedanib

(2015) Banu A. Karimi-Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

(2015) Aparna Jayachandran et al.   Oncotarget

Immune modulatory therapies for spinal cord injury – Past, present and future

(2014) Jason R. Plemel et al.   EXPERIMENTAL NEUROLOGY

Comparative study between Ephedra sinica Stapf and Fructus Schisandrae Chinensis on ET-1 and 6-keto-prostaglandin F1α in rats with idiopathic pulmonary fibrosis

(2014) H.Q. Zhai et al.   GENETICS AND MOLECULAR RESEARCH

IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice

(2014) Dong Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Targeting TLR2 Attenuates Pulmonary Inflammation and Fibrosis by Reversion of Suppressive Immune Microenvironment

(2014) H.-Z. Yang et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis

(2014) Bo Tao et al.   JOURNAL OF IMMUNOLOGY

In Vivo Characterization of Alveolar and Interstitial Lung Macrophages in Rhesus Macaques: Implications for Understanding Lung Disease in Humans

(2014) Y. Cai et al.   JOURNAL OF IMMUNOLOGY

Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination

(2014) Feng Xie et al.   Cells

FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis

(2013) Qiang Ding et al.   AMERICAN JOURNAL OF PATHOLOGY

Multiplex protein profiling of bronchoalveolar lavage in idiopathic pulmonary fibrosis and hypersensitivity pneumonitis

(2013) AWuyts Wim et al.   Annals of Thoracic Medicine

Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways

(2013) Haixia Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of the TGF-β/BMP-7/Smad pathways in renal diseases

(2012) Xiao-Ming Meng et al.   CLINICAL SCIENCE

Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation

(2012) Hui Yao Lan   International Journal of Biological Sciences

Pulmonary fibrosis: patterns and perpetrators

(2012) Paul W. Noble et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β/Smad Signaling in Kidney Disease

(2012) Hui Y. Lan et al.   SEMINARS IN NEPHROLOGY

The Lung Macrophage: A Jack of All Trades

(2011) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

The pathogenesis of idiopathic pulmonary fibrosis

(2010) William R. Coward et al.   Therapeutic Advances in Respiratory Disease