Functional information from clinically-derived drug resistant forms of the Candida glabrata Pdr1 transcription factor

Role of Mediator in virulence and antifungal drug resistance in pathogenic fungi

(2019) Gary P. Moran et al.   CURRENT GENETICS

Twenty Years of the SENTRY Antifungal Surveillance Program: Results for Candida Species From 1997–2016

(2019) Michael A Pfaller et al.   Open Forum Infectious Diseases

Twenty years of Mediator complex structural studies

(2019) Alexis Verger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Positive autoregulation and repression of transactivation are key regulatory features of the Candida glabrata Pdr1 transcription factor

(2018) Svetlana Khakhina et al.   MOLECULAR MICROBIOLOGY

High‐throughput discovery of functional disordered regions: investigation of transactivation domains

(2018) Charles NJ Ravarani et al.   Molecular Systems Biology

Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

(2018) Sarah G. Whaley et al.   mSphere

Multiple interfaces control activity of the Candida glabrata Pdr1 transcription factor mediating azole drug resistance

(2018) W. Scott Moye-Rowley   CURRENT GENETICS

Are In Vitro Susceptibilities to Azole Antifungals Predictive of Clinical Outcome in the Treatment of Candidemia?

(2018) Twisha S. Patel et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Negative regulation of Candida glabrata Pdr1 by the deubiquitinase subunit Bre5 occurs in a ubiquitin independent manner

(2018) Sanjoy Paul et al.   MOLECULAR MICROBIOLOGY

The unmet clinical need of novel antifungal drugs

(2017) Damian J. Krysan   Virulence

Antifungal Susceptibility Testing Practices at Acute Care Hospitals Enrolled in the National Healthcare Safety Network, United States, 2011–2015

(2017) Snigdha Vallabhaneni et al.   Open Forum Infectious Diseases

Antifungal Agents

(2016) Jeniel E. Nett et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction

(2016) Joy L. Nishikawa et al.   NATURE

Azole Resistance in Candida glabrata

(2016) Sarah G. Whaley et al.   Current Infectious Disease Reports

The 9aaTAD Transactivation Domains: From Gal4 to p53

(2016) Martin Piskacek et al.   PLoS One

Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

(2015) Alia A. Sagatova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of Genomic Binding Sites for Candida glabrata Pdr1 Transcription Factor in Wild-Type and ρ0Cells

(2014) Sanjoy Paul et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface

(2014) L. Warfield et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

Expression Plasmids for Use in Candida glabrata

(2013) Rebecca E. Zordan et al.   G3-Genes Genomes Genetics

Regulation of the CgPdr1 Transcription Factor from the Pathogen Candida glabrata

(2010) Sanjoy Paul et al.   EUKARYOTIC CELL

Differential Roles of Transcriptional Mediator Subunits in Regulation of Multidrug Resistance Gene Expression in Saccharomyces cerevisiae

(2010) Puja Shahi et al.   MOLECULAR BIOLOGY OF THE CELL

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

(2009) Sélène Ferrari et al.   PLoS Pathogens

A nuclear receptor-like pathway regulating multidrug resistance in fungi

(2008) Jitendra K. Thakur et al.   NATURE