Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis

Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis

(2019) Zhixiu Li et al.   PLoS Genetics

Killer cell immunoglobulin–like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1

(2018) Maureen P. Martin et al.   JOURNAL OF CLINICAL INVESTIGATION

Genotype B of Killer Cell Immunoglobulin-Like Receptor is Related with Gastric Cancer Lesions

(2018) Eric G. Hernandez et al.   Scientific Reports

HLA and KIR Associations of Cervical Neoplasia

(2018) Xiao Bao et al.   JOURNAL OF INFECTIOUS DISEASES

Peptide-specific engagement of the activating NK cell receptor KIR2DS1

(2017) Anaïs Chapel et al.   Scientific Reports

Significant association of the KIR2DL3/HLA-C1 genotype with susceptibility to Crohn’s disease

(2016) Roberto Díaz-Peña et al.   HUMAN IMMUNOLOGY

Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

(2016) Philippa M. Saunders et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

(2016) David Ellinghaus et al.   NATURE GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

(2016) Anna Ridley et al.   Arthritis & Rheumatology

HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1

(2016) Aura Burian et al.   PLoS One

Imputation of KIR Types from SNP Variation Data

(2015) Damjan Vukcevic et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A bird's eye view of NK cell receptor interactions with their MHC class I ligands

(2015) Philippa M. Saunders et al.   IMMUNOLOGICAL REVIEWS

KIR3DS1-Specific D0 Domain Polymorphisms Disrupt KIR3DL1 Surface Expression and HLA Binding

(2015) Tiernan J. Mulrooney et al.   JOURNAL OF IMMUNOLOGY

Peptide-Dependent Recognition of HLA-B*57:01 by KIR3DS1

(2015) Geraldine M. O'Connor et al.   JOURNAL OF VIROLOGY

Dominant Role of the ERAP1 Polymorphism R528K in Shaping the HLA-B27 Peptidome Through Differential Processing Determined by Multiple Peptide Residues

(2015) Alejandro Sanz-Bravo et al.   Arthritis & Rheumatology

Polymorphic Sites Away from the Bw4 Epitope That Affect Interaction of Bw4+ HLA-B with KIR3DL1

(2014) B. Sanjanwala et al.   JOURNAL OF IMMUNOLOGY

Synergistic Polymorphism at Two Positions Distal to the Ligand-Binding Site Makes KIR2DL2 a Stronger Receptor for HLA-C Than KIR2DL3

(2014) A. K. Moesta et al.   JOURNAL OF IMMUNOLOGY

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations

(2014) Faviel F. González-Galarza et al.   NUCLEIC ACIDS RESEARCH

Development of a Novel Multiplex PCR Assay to Detect Functional Subtypes of KIR3DL1 Alleles

(2014) Jeanette E. Boudreau et al.   PLoS One

Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11

(2014) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic risk for co-occurrence of type 1 diabetes and celiac disease is modified by HLA-C and killer immunoglobulin-like receptors

(2014) D. Smigoc Schweiger et al.   TISSUE ANTIGENS

Large Spectrum of HLA-C Recognition by Killer Ig-like Receptor (KIR)2DL2 and KIR2DL3 and Restricted C1 Specificity of KIR2DS2: Dominant Impact of KIR2DL2/KIR2DS2 on KIR2D NK Cell Repertoire Formation

(2013) G. David et al.   JOURNAL OF IMMUNOLOGY

Allelic Variation in KIR2DL3 Generates a KIR2DL2-like Receptor with Increased Binding to its HLA-C Ligand

(2013) W. R. Frazier et al.   JOURNAL OF IMMUNOLOGY

KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis

(2013) I. Wong-Baeza et al.   JOURNAL OF IMMUNOLOGY

HLA-F and MHC Class I Open Conformers Are Ligands for NK Cell Ig-like Receptors

(2013) J. P. Goodridge et al.   JOURNAL OF IMMUNOLOGY

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

(2013) Adrian Cortes et al.   NATURE GENETICS

Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors

(2012) W. Jiang et al.   GENOME RESEARCH

IPD—the Immuno Polymorphism Database

(2012) James Robinson et al.   NUCLEIC ACIDS RESEARCH

Significant Association of KIR2DL3-HLA-C1 Combination with Cerebral Malaria and Implications for Co-evolution of KIR and HLA

(2012) Kouyuki Hirayasu et al.   PLoS Pathogens

Molecular Recognition of Paired Receptors in the Immune System

(2012) Kimiko Kuroki et al.   Frontiers in Microbiology

ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity

(2011) L. Ulianich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

KIR3DL1+HLA-B Bw4Ile80 and KIR2DS1+HLA-C2 combinations are both associated with ankylosing spondylitis in the Iranian population

(2011) N. Tajik et al.   International Journal of Immunogenetics

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis

(2010) Roberto Díaz-Peña et al.   ARTHRITIS AND RHEUMATISM

Contribution of functional KIR3DL1 to ankylosing spondylitis

(2010) Ivan V Zvyagin et al.   Cellular & Molecular Immunology

Polymorphisms of KIR Gene and HLA-C Alleles: Possible Association with Susceptibility to HLA-B27-Positive Patients with Ankylosing Spondylitis

(2010) Yu-Lian Jiao et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

(2010) John D Reveille et al.   NATURE GENETICS

Does the KIR2DS5 Gene Protect from Some Human Diseases?

(2010) Izabela Nowak et al.   PLoS One

Different Patterns of Evolution in the Centromeric and Telomeric Regions of Group A and B Haplotypes of the Human Killer Cell Ig-Like Receptor Locus

(2010) Chul-Woo Pyo et al.   PLoS One

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C

(2009) Thorsten Graef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Long-Range LD Can Confound Genome Scans in Admixed Populations

(2008) Alkes L. Price et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis

(2008) D Harvey et al.   ANNALS OF THE RHEUMATIC DISEASES

Human leukocyte antigens A23, A24, and A32 but not A25 are ligands for KIR3DL1

(2008) M. Stern et al.   BLOOD

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

(2008) D. Pende et al.   BLOOD

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Activating KIR genes are associated with ankylosing spondylitis in Asian populations

(2008) Roberto Díaz-Peña et al.   HUMAN IMMUNOLOGY

Polymorphisms of KIRs Gene and HLA-C Alleles in Patients with Ankylosing Spondylitis: Possible Association with Susceptibility to the Disease

(2008) Yu-Lian Jiao et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris

(2008) M. Jobim et al.   TISSUE ANTIGENS