Human Retinal Microvasculature‐on‐a‐Chip for Drug Discovery

Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance

(2020) Filip Roudnicky et al.   Scientific Reports

Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells

(2020) Filip Roudnicky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organ-On-A-Chip Technologies for Advanced Blood–Retinal Barrier Models

(2019) Héloïse Ragelle et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Polarised VEGFA Signalling at Vascular Blood–Neural Barriers

(2018) Silvia Dragoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A compartmentalized microfluidic chip with crisscross microgrooves and electrophysiological electrodes for modeling the blood–retinal barrier

(2018) Jose Yeste et al.   LAB ON A CHIP

Organ-on-a-chip technologies that can transform ophthalmic drug discovery and disease modeling

(2018) Jasmin C. Haderspeck et al.   Expert Opinion on Drug Discovery

Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation

(2017) Brian Wai Chow et al.   NEURON

Architecture in 3D cell culture: An essential feature for in vitro toxicology

(2017) Sophie A. Lelièvre et al.   TOXICOLOGY IN VITRO

The inner blood-retinal barrier: Cellular basis and development

(2017) Mónica Díaz-Coránguez et al.   VISION RESEARCH

Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes

(2017) Sebastiaan J. Trietsch et al.   Nature Communications

A Low Permeability Microfluidic Blood-Brain Barrier Platform with Direct Contact between Perfusable Vascular Network and Astrocytes

(2017) Seokyoung Bang et al.   Scientific Reports

96 perfusable blood vessels to study vascular permeability in vitro

(2017) V. van Duinen et al.   Scientific Reports

Engineering growth factors for regenerative medicine applications

(2016) Aaron C. Mitchell et al.   Acta Biomaterialia

Pitfalls in assessing microvascular endothelial barrier function: impedance-based devices versus the classic macromolecular tracer assay

(2016) Iris Bischoff et al.   Scientific Reports

Cooperative Effects of Matrix Stiffness and Fluid Shear Stress on Endothelial Cell Behavior

(2015) Julie C. Kohn et al.   BIOPHYSICAL JOURNAL

Angiogenesis and Eye Disease

(2015) Yoshihiko Usui et al.   Annual Review of Vision Science

A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip

(2015) Sudhir P. Deosarkar et al.   PLoS One

Differential Apicobasal VEGF Signaling at Vascular Blood-Neural Barriers

(2014) Natalie Hudson et al.   DEVELOPMENTAL CELL

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

Mechanotransduction and extracellular matrix homeostasis

(2014) Jay D. Humphrey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endothelial barrier disruption and recovery is controlled by substrate stiffness

(2013) Anna A. Birukova et al.   MICROVASCULAR RESEARCH

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Alterations to the Blood–Retinal Barrier in Diabetes: Cytokines and Reactive Oxygen Species

(2011) Tiffany Frey et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of shear stress in Blood-Brain Barrier endothelial physiology

(2011) Luca Cucullo et al.   BMC NEUROSCIENCE

A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes

(2011) Joanna Wisniewska-Kruk et al.   EXPERIMENTAL EYE RESEARCH

Phaseguides: a paradigm shift in microfluidic priming and emptying

(2011) Paul Vulto et al.   LAB ON A CHIP

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces

(2010) Ramaswamy Krishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of mechanical factors on the function of engineered human blood microvessels in microfluidic collagen gels

(2010) Gavrielle M. Price et al.   BIOMATERIALS

TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

(2010) C. A. Aveleira et al.   DIABETES

Blood-Retinal Barrier

(2010) José Cunha-Vaz et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

ON THE OCCURRENCE IN THE RETINA OF CONDITIONS CORRESPONDING TO THE «BLOOD-BRAIN BARRIER»

(2009) Erik Palm   ACTA OPHTHALMOLOGICA

In vitroVasculogenesis Models Revisited - Measurement of VEGF Diffusion in Matrigel

(2009) T. Miura et al.   Mathematical Modelling of Natural Phenomena