Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution
Authors
Keywords
-
Journal
Scientific Reports
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-10-12
DOI
10.1038/s41598-020-74095-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Biological plasticity rescues target activity in CRISPR knock outs
- (2019) Arne H. Smits et al. NATURE METHODS
- An overview of mammalian mitochondrial DNA replication mechanisms
- (2018) Takehiro Yasukawa et al. JOURNAL OF BIOCHEMISTRY
- Tissue specific differences in mitochondrial DNA maintenance and expression
- (2018) Elena Herbers et al. MITOCHONDRION
- SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts
- (2018) Min Li et al. Nature Communications
- The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism
- (2017) Sebastian Kaiser et al. Nature Communications
- TIMELESS Suppresses the Accumulation of Aberrant CDC45·MCM2-7·GINS Replicative Helicase Complexes on Human Chromatin
- (2016) Xiaohua Xu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases
- (2016) Francesca Marino et al. Scientific Reports
- Altered mitochondrial DNA copy number contributes to human cancer risk: evidence from an updated meta-analysis
- (2016) Liwen Hu et al. Scientific Reports
- RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells
- (2015) Jun-Sub Im et al. CELL CYCLE
- Borrowing Nuclear DNA Helicases to Protect Mitochondrial DNA
- (2015) Lin Ding et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Replication-transcription switch in human mitochondria
- (2015) K. Agaronyan et al. SCIENCE
- RECQ5-dependent SUMOylation of DNA topoisomerase I prevents transcription-associated genome instability
- (2015) Min Li et al. Nature Communications
- Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly
- (2014) Jonas Mengel-From et al. HUMAN GENETICS
- Reduction in mitochondrial DNA copy number in peripheral leukocytes after onset of Huntington's disease
- (2014) Maria Hvidberg Petersen et al. MITOCHONDRION
- Impaired p32 Regulation Caused by the Lymphoma-Prone RECQ4 Mutation Drives Mitochondrial Dysfunction
- (2014) Jiin-Tarng Wang et al. Cell Reports
- RECQL4 and p53 potentiate the activity of polymerase γ and maintain the integrity of the human mitochondrial genome
- (2013) Shruti Gupta et al. CARCINOGENESIS
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Mitochondrial DNA replication proceeds via a ‘bootlace’ mechanism involving the incorporation of processed transcripts
- (2013) Aurelio Reyes et al. NUCLEIC ACIDS RESEARCH
- RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
- (2012) Deborah L. Croteau et al. AGING CELL
- RecQL4 cytoplasmic localization: Implications in mitochondrial DNA oxidative damage repair
- (2012) Zhenfen Chi et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress
- (2012) S. De et al. JOURNAL OF CELL SCIENCE
- Maintenance of mitochondrial DNA copy number is essential for osteoclast survival
- (2012) Tsuyoshi Miyazaki et al. ARTHRITIS RESEARCH & THERAPY
- Human Mitochondrial DNA Replication
- (2012) I. J. Holt et al. Cold Spring Harbor Perspectives in Biology
- Mitochondrial Dysfunction in Cancer Cells Due to Aberrant Mitochondrial Replication
- (2011) Yuriy Shapovalov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Generation, function and diagnostic value of mitochondrial DNA copy number alterations in human cancers
- (2011) Man Yu LIFE SCIENCES
- Rothmund–Thomson syndrome helicase, RECQ4: On the crossroad between DNA replication and repair
- (2010) Yilun Liu DNA REPAIR
- Human RECQ1 and RECQ4 Helicases Play Distinct Roles in DNA Replication Initiation
- (2010) S. Thangavel et al. MOLECULAR AND CELLULAR BIOLOGY
- MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication
- (2009) Xiaohua Xu et al. EMBO JOURNAL
- Dual DNA unwinding activities of the Rothmund–Thomson syndrome protein, RECQ4
- (2009) Xiaohua Xu et al. EMBO JOURNAL
- Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins
- (2009) J.-S. Im et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma
- (2008) Q. Lan et al. BLOOD
- The mutation spectrum in RECQL4 diseases
- (2008) H Annika Siitonen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Sensitivity of RECQL4-deficient fibroblasts from Rothmund–Thomson syndrome patients to genotoxic agents
- (2008) Weidong Jin et al. HUMAN GENETICS
- Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone-resorbing activity, and apoptosis pathway
- (2008) T. Akiyama et al. MOLECULAR CANCER THERAPEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started