Wogonin Ameliorates Renal Inflammation and Fibrosis by Inhibiting NF-κB and TGF-β1/Smad3 Signaling Pathways in Diabetic Nephropathy

Uncovering the Mechanism of Astragalus membranaceus in the Treatment of Diabetic Nephropathy Based on Network Pharmacology

(2020) Ming-Fei Guo et al.   Journal of Diabetes Research

Cyanidin-3-glucoside from Black Rice Ameliorates Diabetic Nephropathy via Reducing Blood Glucose, Suppressing Oxidative Stress and Inflammation, and Regulating Transforming Growth Factor β1/Smad Expression

(2020) Hong Xing Zheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy

(2020) Xue-qi Liu et al.   BIOCHEMICAL PHARMACOLOGY

Can Wogonin be used in Controlling Diabetic Cardiomyopathy?

(2019) Shahzad Khan et al.   CURRENT PHARMACEUTICAL DESIGN

Blockade of the Adenosine A3 Receptor Attenuates Caspase 1 Activation in Renal Tubule Epithelial Cells and Decreases Interleukins IL-1β and IL-18 in Diabetic Rats

(2019) Wallys Garrido et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deletion of Smad3 prevents renal fibrosis and inflammation in type 2 diabetic nephropathy

(2019) Bi-Hua Xu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs

(2018) Patrick Ming-Kuen Tang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Targeting inflammation in diabetic nephropathy: a tale of hope

(2018) Juan Antonio Moreno et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis

(2017) Xiao-Ming Meng et al.   LABORATORY INVESTIGATION

Anti-fibrotic effect of wogonin in renal tubular epithelial cells via Smad3-dependent mechanisms

(2016) Xiao-Ming Meng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti–TGF-β1 Antibody Therapy in Patients with Diabetic Nephropathy

(2016) James Voelker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wogonin attenuates diabetic cardiomyopathy through its anti-inflammatory and anti-oxidative properties

(2016) Shahzad Khan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Elsholtzia ciliata (Thunb.) Hylander attenuates renal inflammation and interstitial fibrosis via regulation of TGF-ß and Smad3 expression on unilateral ureteral obstruction rat model

(2016) Tae-Won Kim et al.   PHYTOMEDICINE

Corosolic acid inhibits the proliferation of glomerular mesangial cells and protects against diabetic renal damage

(2016) Xiao-Qiang Li et al.   Scientific Reports

Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo

(2015) Sae-Kwang Ku et al.   BMB Reports

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway

(2015) Sambasiva Rao Kolati et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Kaempferol alleviates insulin resistance via hepatic IKK/NF-κB signal in type 2 diabetic rats

(2015) Cheng Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-κB signaling pathway in vivo and in vitro

(2015) YAN WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?

(2015) Ivonne Loeffler et al.   Cells

Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice

(2013) Eun-Jung Bak et al.   CLINICAL NUTRITION

Mesangial cell biology

(2012) Hanna E. Abboud   EXPERIMENTAL CELL RESEARCH

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

Blockade of Endothelial-Mesenchymal Transition by a Smad3 Inhibitor Delays the Early Development of Streptozotocin-Induced Diabetic Nephropathy

(2010) J. Li et al.   DIABETES

Pathogenic perspectives for the role of inflammation in diabetic nephropathy

(2009) Antonio Rivero et al.   CLINICAL SCIENCE

The Mesangial Cell Revisited: No Cell Is an Island

(2009) D. Schlondorff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum Concentrations of Markers of TNF  and Fas-Mediated Pathways and Renal Function in Nonproteinuric Patients with Type 1 Diabetes

(2008) M. A. Niewczas et al.   Clinical Journal of the American Society of Nephrology