Identification of a Novel c-Myc Inhibitor 7594-0037 by Structure-Based Virtual Screening and Investigation of Its Anti-Cancer Effect on Multiple Myeloma

Assessing the performance of three resveratrol in binding with SIRT1 by molecular dynamics simulation and MM/GBSA methods: the weakest binding of resveratrol 3 to SIRT1 triggers a possibility of dissociation from its binding site

(2019) Han Chen et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Lanatoside C inhibits cell proliferation and induces apoptosis through attenuating Wnt/β-catenin/c-Myc signaling pathway in human gastric cancer cell

(2018) Yudong Hu et al.   BIOCHEMICAL PHARMACOLOGY

Scriptaid inhibits cell survival, cell cycle, and promotes apoptosis in multiple myeloma via epigenetic regulation of p21

(2018) Ruosi Yao et al.   EXPERIMENTAL HEMATOLOGY

Insight into the molecular mechanism of yeast acetyl-coenzyme A carboxylase mutants F510I, N485G, I69E, E477R, and K73R resistant to soraphen A

(2018) Jian Gao et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Computational insights into the interaction mechanism of transcription cofactor vestigial-like protein 4 (VGLL4) binding to TEA domain transcription factor 4 (TEAD4) by molecular dynamics simulation and molecular mechanics generalized Born/surface area (MM/GBSA) calculation

(2018) Jian Gao et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy

(2017) Shuai Ji et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Salvianolic Acid A Attenuates Cell Apoptosis, Oxidative Stress, Akt and NF-κB Activation in Angiotensin-II Induced Murine Peritoneal Macrophages

(2016) Ling Li et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Overexpression of c-myc is associated with adverse clinical features and worse overall survival in multiple myeloma

(2016) Agoston Gyula Szabo et al.   LEUKEMIA & LYMPHOMA

p42.3: An Abductor of Cell Cycle

(2015) Wen-Jia Cao et al.   Anti-Cancer Agents in Medicinal Chemistry

Small-molecule inhibitors of the Myc oncoprotein

(2015) Steven Fletcher et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Luteolin Antagonizes Angiotensin II-Dependent Proliferation and Collagen Synthesis of Cultured rat Cardiac Fibroblasts

(2015) Tingting Wang et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Addiction to c-MYC in multiple myeloma

(2012) T. Holien et al.   BLOOD

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma

(2011) W-J Chng et al.   LEUKEMIA

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

(2011) N E Franke et al.   LEUKEMIA

Gene therapy for Multiple Myeloma

(2008) Yasuo Adachi et al.   CURRENT GENE THERAPY

Pim kinase-dependent inhibition of c-Myc degradation

(2008) Y Zhang et al.   ONCOGENE