Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Identification of a novel coronavirus causing severe pneumonia in human

(2020) Li-Li Ren et al.   CHINESE MEDICAL JOURNAL

COVID-19: towards controlling of a pandemic

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Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura

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Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

(2019) Jean K. Millet et al.   Jove-Journal of Visualized Experiments

Caplacizumab as an emerging treatment option for acquired thrombotic thrombocytopenic purpura

(2019) Tugrul Elverdi et al.   Drug Design Development and Therapy

Clinical pharmacology of caplacizumab for the treatment of patients with acquired thrombotic thrombocytopenic purpura

(2019) Maria Laura Sargentini-Maier et al.   Expert Review of Clinical Pharmacology

Caplacizumab treatment for acquired thrombotic thrombocytopenic purpura (HERCULES trial)

(2019) L. J. Estcourt   TRANSFUSION MEDICINE

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

(2019) Yushun Wan et al.   JOURNAL OF VIROLOGY

A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV

(2018) Guangyu Zhao et al.   JOURNAL OF VIROLOGY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

(2018) V. Stalin Raj et al.   Science Advances

Nanobodies as therapeutics: big opportunities for small antibodies

(2016) Sophie Steeland et al.   DRUG DISCOVERY TODAY

Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus

(2016) Gökçe Günaydın et al.   Scientific Reports

NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies

(2016) Sandrine Moutel et al.   eLife

Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake

(2015) Maarten Rotman et al.   NUCLEAR MEDICINE AND BIOLOGY

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

(2015) Davide Corti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies

(2014) Tianlei Ying et al.   JOURNAL OF VIROLOGY

General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold

(2008) Cécile Vincke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY