Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

α-Ketoglutarate links p53 to cell fate during tumour suppression

(2019) John P. Morris et al.   NATURE

ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts

(2018) Grace H Elta et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer

(2018) Xin Tian et al.   CELL RESEARCH

Intraductal Papillary Mucinous Neoplasms of the Pancreas

(2018) Annabelle L. Fonseca et al.   PANCREAS

5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer

(2018) Ji Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

(2018) Shu Yi Shen et al.   NATURE

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

(2018) Joshua Moss et al.   Nature Communications

Pancreatic Adenocarcinoma, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology

(2017) Margaret A. Tempero et al.   Journal of the National Comprehensive Cancer Network

Chromatin dependencies in cancer and inflammation

(2017) Ivan Marazzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

(2016) Kapo Saukkonen et al.   BMC CANCER

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

Biomarkers in pancreatic adenocarcinoma: current perspectives

(2016) Douglas Swords et al.   OncoTargets and Therapy

5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4 + T Cells

(2016) Colm E. Nestor et al.   Cell Reports

Pancreatic cancer

(2016) Jorg Kleeff et al.   Nature Reviews Disease Primers

Chromatin signatures of cancer

(2015) Marc A. Morgan et al.   GENES & DEVELOPMENT

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

(2015) Richard A Moffitt et al.   NATURE GENETICS

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

(2015) Ling Huang et al.   NATURE MEDICINE

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

(2014) Xiaojing Yang et al.   CANCER CELL

Epigenetic stochasticity, nuclear structure and cancer: the implications for medicine

(2014) A. P. Feinberg   JOURNAL OF INTERNAL MEDICINE

Inflammation-Induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by KrasG12D

(2014) S. Baumgart et al.   Cancer Discovery

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

New gene functions in megakaryopoiesis and platelet formation

(2011) Christian Gieger et al.   NATURE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

RUNX1T1

(2011) Aejaz Nasir et al.   PANCREAS

Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

(2011) Keith E. Szulwach et al.   PLoS Genetics

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Epidemiology of Pancreatic Cancer: An Update

(2010) Patrick Maisonneuve et al.   DIGESTIVE DISEASES

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation

(2009) Hongjie Zhang et al.   MECHANISMS OF DEVELOPMENT

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY