Oxidized-LDL inhibits testosterone biosynthesis by affecting mitochondrial function and the p38 MAPK/COX-2 signaling pathway in Leydig cells

HC diet inhibited testosterone synthesis by activating endoplasmic reticulum stress in testicular Leydig cells

(2019) Chunxiao Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

β-Endorphin Induction by Psychological Stress Promotes Leydig Cell Apoptosis through p38 MAPK Pathway in Male Rats

(2019) Xiong et al.   Cells

Analysis of human sperm DNA fragmentation index (DFI) related factors: a report of 1010 subfertile men in China

(2018) Jin-Chun Lu et al.   Reproductive Biology and Endocrinology

Effects of saturated palmitic acid and omega-3 polyunsaturated fatty acids on Sertoli cell apoptosis

(2018) Xuechun Hu et al.   Systems Biology in Reproductive Medicine

Low testosterone in ApoE/LDL receptor double-knockout mice is associated with rarefied testicular capillaries together with fewer and smaller Leydig cells

(2018) Kai Steinfeld et al.   Scientific Reports

Association between leptin, obesity, hormonal interplay and male infertility

(2018) Sofia Amjad et al.   ANDROLOGIA

Rosiglitazone ameliorates palmitic acid-induced cytotoxicity in TM4 Sertoli cells

(2018) Xie Ge et al.   Reproductive Biology and Endocrinology

Relation between circulating oxidized-LDL and metabolic syndrome in children with obesity: the role of hypertriglyceridemic waist phenotype

(2017) Valeria Calcaterra et al.   JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM

High-fat diet aggravates 2,2′,4,4′-tetrabromodiphenyl ether-inhibited testosterone production via DAX-1 in Leydig cells in rats

(2017) Zhan Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Annexin A5 regulates Leydig cell testosterone production via ERK1/2 pathway

(2016) Bing Yao et al.   ASIAN JOURNAL OF ANDROLOGY

Leukemia inhibitory factor stimulates steroidogenesis of rat immature Leydig cells via increasing the expression of steroidogenic acute regulatory protein

(2016) Yiyan Wang et al.   GROWTH FACTORS

Physiology and pathophysiology of oxLDL uptake by vascular wall cells in atherosclerosis

(2016) Natalia Di Pietro et al.   VASCULAR PHARMACOLOGY

Young Men with Poor Cardiorespiratory Fitness Combined with lower Testosterone Have High Levels of Oxidized LDL Lipids—Being Fit Alters This Relationship

(2016) Jussi Kosola et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor

(2015) Koichi Yamamoto et al.   FASEB JOURNAL

Dietary cholesterol and oxidised cholesterol: effects on sperm characteristics, antioxidant status and hormonal profile in rats

(2014) A. Khorrami et al.   ANDROLOGIA

Body mass index, waist-to-hip ratio, waist circumference and waist-to-height ratio cannot predict male semen quality: a report of 1231 subfertile Chinese men

(2014) J.-C. Lu et al.   ANDROLOGIA

The regulation of spermatogenesis by androgens

(2014) Lee B. Smith et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The effect of oxidized low-density lipoprotein (ox-LDL) on radiation-induced endothelial-to-mesenchymal transition

(2013) Miseon Kim et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Impairment of reproductive function in a male rat model of non-alcoholic fatty liver disease and beneficial effect of N-3 fatty acid supplementation

(2013) Yan Li et al.   TOXICOLOGY LETTERS

The Relationship between Testosterone Deficiency and Men's Health

(2013) Akira Tsujimura   World Journal of Mens Health

OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPAR -signaling pathway in macrophages

(2012) X. Yu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Cholesterol and male fertility: What about orphans and adopted?

(2012) Salwan Maqdasy et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Role of Ox-LDL/LOX-1/NF-κB signaling pathway in regulation of atherosclerotic plaque growth by testosterone in male rabbits

(2012) Shijun Li et al.   VASCULAR PHARMACOLOGY

Gonadotropin-releasing hormone positively regulates steroidogenesis via extracellular signal-regulated kinase in rat Leydig cells

(2011) Bing Yao et al.   ASIAN JOURNAL OF ANDROLOGY

Diagnosis and treatment of hypogonadism in men

(2011) Shalender Bhasin et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Atorvastatin suppresses inflammatory response induced by oxLDL through inhibition of ERK phosphorylation, IκBα degradation, and COX-2 expression in murine macrophages

(2011) Qin Shao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Circulating Oxidized LDL and Inflammation in Extreme Pediatric Obesity

(2011) Anne L. Norris et al.   Obesity

Bacterial LPS Mediated Acute Inflammation-induced Spermatogenic Failure in Rats: Role of Stress Response Proteins and Mitochondrial Dysfunction

(2010) Mallikarjuna Reddy Metukuri et al.   INFLAMMATION

Relation of circulating oxidized LDL to obesity and insulin resistance in children

(2010) Aaron S Kelly et al.   PEDIATRIC DIABETES

Oxidized LDL: Diversity, Patterns of Recognition, and Pathophysiology

(2009) Irena Levitan et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitogen-activated protein kinases in male reproductive function

(2009) Michelle W.M. Li et al.   TRENDS IN MOLECULAR MEDICINE

Smoking and low serum testosterone associates with high concentration of oxidized LDL

(2008) Meri S. Linna et al.   ANNALS OF MEDICINE

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

(2008) Richard M. Sharpe et al.   FERTILITY AND STERILITY