Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis

Ets1-Mediated Acetylation of FoxO1 Is Critical for Gluconeogenesis Regulation during Feed-Fast Cycles

(2019) Kai Li et al.   Cell Reports

PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis

(2019) Xueying Ji et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Small molecules as tools to study the chemical epigenetics of lysine acetylation

(2018) Matthias Schiedel et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Modulating the masters: chemical tools to dissect CBP and p300 function

(2018) Meghan E Breen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Novel Mechanism of Foxo1 Phosphorylation in Glucagon Signaling in Control of Glucose Homeostasis

(2018) Yuxin Wu et al.   DIABETES

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

(2017) Loren M. Lasko et al.   NATURE

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

(2017) Jayme L. Dahlin et al.   Nature Communications

Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300

(2016) H. Jane Dyson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Is histone acetylation the most important physiological function for CBP and p300?

(2016) David C. Bedford et al.   Aging-US

Protein Lysine Acetylation by p300/CBP

(2015) Beverley M. Dancy et al.   CHEMICAL REVIEWS

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

(2014) Rebecca A. Haeusler et al.   Nature Communications

Improving Insulin Sensitivity With HDAC Inhibitor

(2013) J. Ye   DIABETES

The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis

(2012) Wilfred Ip et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Disrupting the CH1 Domain Structure in the Acetyltransferases CBP and p300 Results in Lean Mice with Increased Metabolic Control

(2011) David C. Bedford et al.   Cell Metabolism

Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases

(2010) David C. Bedford et al.   Epigenetics

Uncoupling of Acetylation from Phosphorylation Regulates FoxO1 Function Independent of Its Subcellular Localization

(2010) Li Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism

(2010) Bhaskar Ponugoti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

(2010) Julien Bricambert et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Metformin and Insulin Suppress Hepatic Gluconeogenesis through Phosphorylation of CREB Binding Protein

(2009) Ling He et al.   CELL

FXR Acetylation Is Normally Dynamically Regulated by p300 and SIRT1 but Constitutively Elevated in Metabolic Disease States

(2009) Jongsook Kim Kemper et al.   Cell Metabolism

COP1 Functions as a FoxO1 Ubiquitin E3 Ligase to Regulate FoxO1-mediated Gene Expression

(2008) Satomi Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of FoxO in the regulation of metabolism

(2008) D N Gross et al.   ONCOGENE