Article
Medicine, General & Internal
Sung Eun Choi, Corneliu Sima, Laura Pesquera Colom, Giang T. Nguyen, William Giannobile
Summary: This study aimed to evaluate the effectiveness of a surveillance COVID-19 testing program in an academic dental institution. The results showed that implementing an adaptive testing cadence based on individual risk status can reduce the risk of SARS-CoV-2 infection within the institution. Participation in clinical activities did not pose additional risk compared to other in-person activities.
Article
Environmental Sciences
Fuqing Wu, Amy Xiao, Jianbo Zhang, Katya Moniz, Noriko Endo, Federica Armas, Richard Bonneau, Megan A. Brown, Mary Bushman, Peter R. Chai, Claire Duvallet, Timothy B. Erickson, Katelyn Foppe, Newsha Ghaeli, Xiaoqiong Gu, William P. Hanage, Katherine H. Huang, Wei Lin Lee, Mariana Matus, Kyle A. McElroy, Jonathan Nagler, Steven F. Rhode, Mauricio Santillana, Joshua A. Tucker, Stefan Wuertz, Shijie Zhao, Janelle Thompson, Eric J. Alm
Summary: This research shows that longitudinal wastewater analysis can be used to identify trends in disease transmission in advance of clinical case reporting, and infer early viral shedding dynamics for newly infected individuals, which are difficult to capture in clinical investigations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Multidisciplinary Sciences
Ifedayo M. O. Adetifa, Sophie Uyoga, John N. Gitonga, Daisy Mugo, Mark Otiende, James Nyagwange, Henry K. Karanja, James Tuju, Perpetual Wanjiku, Rashid Aman, Mercy Mwangangi, Patrick Amoth, Kadondi Kasera, Wangari Ng'ang'a, Charles Rombo, Christine Yegon, Khamisi Kithi, Elizabeth Odhiambo, Thomas Rotich, Irene Orgut, Sammy Kihara, Christian Bottomley, Eunice W. Kagucia, Katherine E. Gallagher, Anthony Etyang, Shirine Voller, Teresa Lambe, Daniel Wright, Edwine Barasa, Benjamin Tsofa, Philip Bejon, Lynette Ochola-Oyier, Ambrose Agweyu, J. Anthony G. Scott, George M. Warimwe
Summary: A study conducted in Kenya found that while the seroprevalence of SARS-CoV-2 antibodies among blood donors was relatively low, there was evidence of widespread transmission with low associated mortality. This suggests that although many individuals in Kenya remained susceptible to COVID-19, the virus had already spread widely throughout the country.
NATURE COMMUNICATIONS
(2021)
Article
Immunology
David Leeman, Joe Flannagan, Dimple Chudasama, Kyle Dack, Charlotte Anderson, Gavin Dabrera, Theresa Lamagni
Summary: During September to December 2020, there were 53,430 student case-patients of COVID-19 among university students returning to campus in England, accounting for 2.7% of all cases during that period. The number of student case-patients increased rapidly after the start of the term, mainly driven by cases and outbreaks in student accommodations. Case rates among students aged 18-23 doubled at the beginning of the term in towns with universities. These findings highlight the importance of implementing face-to-face and control measures to reduce virus transmission.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Courtney R. Lane, Norelle L. Sherry, Ashleigh F. Porter, Sebastian Duchene, Kristy Horan, Patiyan Andersson, Mathilda Wilmot, Annabelle Turner, Sally Dougall, Sandra A. Johnson, Michelle Sait, Anders Gonsalves da Silva, Susan A. Ballard, Tuyet Hoang, Timothy P. Stinear, Leon Caly, Vitali Sintchenko, Rikki Graham, Jamie McMahon, David Smith, Lex E. X. Leong, Ella M. Meumann, Louise Cooley, Benjamin Schwessinger, William Rawlinson, Sebastiaan J. van Hal, Nicola Stephens, Mike Catton, Clare Looker, Simon Crouch, Brett Sutton, Charles Alpren, Deborah A. Williamson, Torsten Seemann, Benjamin P. Howden
Summary: This study conducted genomic sequencing of COVID-19 cases in Victoria, Australia, identifying the source of the second wave outbreak and showing the effectiveness of genomic epidemiology in eliminating COVID-19 for a second time. The results indicated that a single incursion from hotel quarantine led to a large outbreak, but strict interventions and decisive public health responses were successful in controlling the spread. Real-time genomic surveillance played a crucial role in shaping public health strategies during the outbreak.
LANCET PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Philippe Lemey, Nick Ruktanonchai, Samuel L. Hong, Vittoria Colizza, Chiara Poletto, Frederik Van den Broeck, Mandev S. Gill, Xiang Ji, Anthony Levasseur, Bas B. Oude Munnink, Marion Koopmans, Adam Sadilek, Shengjie Lai, Andrew J. Tatem, Guy Baele, Marc A. Suchard, Simon Dellicour
Summary: In late summer 2020, more than half of the SARS-CoV-2 lineages circulating in many European countries resulted from new introductions, and the success in onward transmission of these newly introduced lineages was negatively associated with the local incidence of COVID-19. The widespread dissemination of variants in summer 2020 highlights the threat of viral spread when restrictions are lifted.
Editorial Material
Biochemical Research Methods
Sergey Knyazev, Karishma Chhugani, Varuni Sarwal, Ram Ayyala, Harman Singh, Smruthi Karthikeyan, Dhrithi Deshpande, Pelin Icer Baykal, Zoia Comarova, Angela Lu, Yuri Porozov, Tetyana Vasylyeva, Joel O. Wertheim, Braden T. Tierney, Charles Y. Chiu, Ren Sun, Aiping Wu, Malak S. Abedalthagafi, Victoria M. Pak, Shivashankar H. Nagaraj, Adam L. Smith, Pavel Skums, Bogdan Pasaniuc, Andrey Komissarov, Christopher E. Mason, Eric Bortz, Philippe Lemey, Fyodor Kondrashov, Niko Beerenwinkel, Tommy Tsan-Yuk Lam, Nicholas C. Wu, Alex Zelikovsky, Rob Knight, Keith A. Crandall, Serghei Mangul
Summary: During the COVID-19 pandemic, genomics and bioinformatics have become crucial tools in public health. They have been used to acquire genomic data that support global health responses, aid in the development of testing methods, and enable the timely tracking of novel SARS-CoV-2 variants. However, the rapid generation and analysis of genomic data present unique technical, scientific, and organizational challenges.
Article
Food Science & Technology
Williara Queiroz de Oliveira, Henriette Monteiro Cordeiro de Azeredo, Iramaia Angelica Neri-Numa, Glaucia Maria Pastore
Summary: Due to the COVID-19 crisis, consumer behavior changes have led to increased use and disposal of food packaging, with technological solutions such as biodegradable packaging and active antiviral components being presented to minimize environmental impacts. The adoption of bioplastics like polylactide (PLA) and incorporation of active components can reduce environmental footprints from food packaging and surface-mediated cross-contamination.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Environmental Sciences
Yongtao Cao, Roland Francis
Summary: This study aimed to investigate the association between SARS-CoV-2 wastewater concentrations and COVID-19 cases at the community-level, and to assess the integration of this data into a wastewater-based epidemiological statistical model for accurate forecasting of COVID-19 infections. The results show that a VAR(1) model estimated with the original data has the strongest forecasting ability, with forecast accuracy for 1 week, 2 weeks, and 3 weeks in the future ranging from 8.97% to 21.57%.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Medicine, General & Internal
Dan H. Barouch
Summary: This article reviews the protective effects of vaccination and prior infection on severe Covid-19, and proposes future research directions.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Infectious Diseases
Jenifer Mallavarpu Ambrose, Vishnu Priya Veeraraghavan, Malathi Kullappan, Poongodi Chellapandiyan, Surapaneni Krishna Mohan, Vivek Anand Manivel
Summary: The global concern over the current dynamics of the COVID-19 pandemic is heightened by the emergence of different virus variants. Research indicates that these variants may pose higher transmission risks but have less impact on health outcomes. Studies suggest that these variants exhibit increased viral antigenicity, moderate to high immunogenicity, potentially leading to stronger neutralizing abilities, thus enhancing epidemiological adaptability.
Article
Multidisciplinary Sciences
Qin Liu, Qi Su, Fen Zhang, Hein M. Tun, Joyce Wing Yan Mak, Grace Chung-Yan Lui, Susanna So Shan Ng, Jessica Y. L. Ching, Amy Li, Wenqi Lu, Chenyu Liu, Chun Pan Cheung, David S. C. Hui, Paul K. S. Chan, Francis Ka Leung Chan, Siew C. Ng
Summary: By integrating clinical features and multi-omics data, the authors identified specific gut microbiome patterns associated with disease severity and development of post-acute COVID-19 syndrome. These findings highlight the potential utility of host phenotype and multi-kingdom microbiota profiling as a prognostic tool for patients with COVID-19.
NATURE COMMUNICATIONS
(2022)
Article
Microbiology
Hong-Ling Jia, Peng Li, Hong-Jie Liu, Jia-Yong Zhong, Peng-Zhe Qin, Wen-Zhe Su, Ying-Feng Zheng, Kui-Biao Li, Qing Zeng, Jin-Hui Li, Li-Zhong Li, Lan Cao, Ji-Bin Wu, Yi-Yun Chen, Lei-Li Jia, Hong-Bin Song, Qi-Wei Zhang, Guang Yang, Chun-Xia Jing, Xiao-Chen Bo, Zhou-Bin Zhang, Biao Di, Chuan-Le Xiao, Ming Ni
Summary: The study shows that in Guangzhou, China, a small outbreak was monitored with comprehensive genomic surveillance of SARS-CoV-2. Despite diverse viral variants in imported cases, local transmission was mainly traced back to specific variants imported from Africa.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Editorial Material
Immunology
Rustom Antia, M. Elizabeth Halloran
Summary: The article discusses the basic concepts underlying the transition from an epidemic to an endemic state, as well as the implications of this transition for COVID-19.
Review
Environmental Sciences
Demian S. Barcellos, Carlos E. R. Barquilha, Pamela E. Oliveira, Mario Prokopiuk, Ramiro G. Etchepare
Summary: Wastewater-based epidemiology (WBE) has significantly developed during the COVID-19 pandemic, with widespread global application in monitoring the spread of the SARS-CoV-2 virus in urban communities. This mini-review examines the impact of the pandemic on WBE, based on the analysis of 1305 scientific reports. The findings demonstrate the migration of WBE's focus to studying the coronavirus and changes in research funding sources, collaborators, and study subjects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Infectious Diseases
Mihaly Sulyok, Mark Walker
Summary: By examining the correlation between social activities and STI incidence, it was found that social restrictions during the COVID-19 pandemic may have led to a reduction in STI cases. The study highlights the ongoing need for sexual health services during the pandemic.
SEXUALLY TRANSMITTED INFECTIONS
(2022)
Article
Infectious Diseases
Tamas Ferenci, Balazs Sarkadi
Summary: Limited information is available on the effectiveness of the BBIBP-CorV vaccine, especially in the elderly. The study found that antibody production after BBIBP-CorV vaccination was significantly reduced with increasing age, with up to 50% of elderly individuals unable to produce protective antibodies. Proper measures should be taken to prevent a potential outbreak of COVID-19 in BBIBP-CorV vaccinated but eventually unprotected elderly individuals.
BMC INFECTIOUS DISEASES
(2022)
Article
Mathematics, Interdisciplinary Applications
Levente Kovacs, Bence Czako, Mate Siket, Tamas Ferenci, Andras Furedi, Balazs Gombos, Gergely Szakacs, Daniel Andras Drexler
Summary: An algorithm for optimizing cancer therapy using control engineering approach is proposed and tested in a mouse model. The results demonstrate that remission can be induced within a 28-day interval using the algorithm.
Letter
Public, Environmental & Occupational Health
Tamas Ferenci
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Surgery
Endre Kolossvary, Tamas Ferenci, Tamas Kovats, Peter Sotonyi, Zoltan Szeberin, Balazs Nemes, Edit Dosa, Katalin Farkas, Zoltan Jarai
Summary: The study assessed the variations in the use of lower extremity vascular surgeries in small geographic areas in Hungary from 2013 to 2017. A new metric was introduced to estimate unwarranted clinical variations in revascularization practice. The results showed significant spatial differences in the likelihood of lower extremity revascularization procedures among patients in different locations, possibly due to issues in vascular service organization.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Letter
Immunology
Haken Lane, Mark David Walker
INTERNATIONAL JOURNAL OF STD & AIDS
(2022)
Article
Multidisciplinary Sciences
Zsombor Zrubka, Aron Kincses, Tamas Ferenci, Levente Kovacs, Laszlo Gulacsi, Marta Pentek
Summary: This study compares the actuarial and subjective estimates of healthy life expectancy (HLE) in the Hungarian general population aged 50 and above, and explores the determinants of individual variance in subjective life expectancy (sLE) and subjective HLE (sHLE).
Article
Peripheral Vascular Disease
Endre Kolossvary, Marton Kolossvary, Tamas Ferenci, Tamas Kovats, Katalin Farkas, Zoltan Jarai
Summary: There are significant spatial variations in lower limb major amputations in Hungary, and healthcare and socio-economic factors play a crucial role in explaining these disparities.
VASA-EUROPEAN JOURNAL OF VASCULAR MEDICINE
(2022)
Article
Dermatology
Mark David Walker, Mihaly Sulyok
Summary: By analyzing internet search data in the UK, the study found that the COVID-19 pandemic restrictions have had a significant impact on the incidence of head lice, while school holidays and attendance did not show a noticeable influence.
PEDIATRIC DERMATOLOGY
(2023)
Letter
Dermatology
Mark D. Walker
INTERNATIONAL JOURNAL OF DERMATOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Tamas Ferenci, Peter Hari, Peter Vajer, Andras Janosi
Summary: This study aimed to validate the GRACE risk score in Hungarian patients with myocardial infarction and found that the GRACE risk score was effective in predicting high-risk patients.
IJC HEART & VASCULATURE
(2023)
Article
Health Care Sciences & Services
Tamas Ferenci
Summary: This study aimed to reproduce the issues with WHO's mortality estimates using synthetic datasets and found that better parameter choices can greatly improve the performance of the method. The results also showed that no single method consistently outperformed the others in all scenarios, highlighting the importance of careful parameter selection and visualization of data.
BMC MEDICAL RESEARCH METHODOLOGY
(2023)
Article
Automation & Control Systems
Levente Kovacs, Tamas Ferenci, Balazs Gombos, Andras Furedi, Imre Rudas, Gergely Szakacs, Daniel Andras Drexler
Summary: Chemotherapy optimization based on mathematical models is a promising direction of personalized medicine. Personalizing treatments can lead to advantages such as reducing side effects and lowering costs. The introduced personalized therapy algorithms significantly increased overall survival in mouse experiments.
IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS
(2023)
Article
Cardiac & Cardiovascular Systems
Robert Edfors, Tomas Jernberg, Christian Lewinter, Mai Blondal, Jaan Eha, Piret Loiveke, Toomas Marandi, Tiia Ainla, Aet Saar, Gudrun Veldre, Tamas Ferenci, Peter Andreka, Andras Janosi, Jarle Jortveit, Sigrun Halvorsen
Summary: This study aimed to compare the baseline characteristics, in-hospital management, and mortality of non-ST-elevation myocardial infarction (NSTEMI) patients in different European countries. The study found differences in age, smoking rates, diabetes, and hypertension proportions among patients from different countries. The proportions of coronary angiographies and percutaneous coronary interventions also varied between countries. Additionally, there were differences in 1-month and 1-year mortality rates among patients from different countries.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2022)
Article
Cardiac & Cardiovascular Systems
Mai Blondal, Tiia Ainla, Jaan Eha, Piret Loiveke, Toomas Marandi, Aet Saar, Gudrun Veldre, Robert Edfors, Christian Lewinter, Tomas Jernberg, Jarle Jortveit, Sigrun Halvorsen, David Becker, Zoltan Csanadi, Tamas Ferenci, Peter Andreka, Andras Janosi
Summary: This study compares the characteristics, management, and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) in Estonia, Hungary, Norway, and Sweden based on data from national ongoing myocardial infarction registries. The findings provide new insights into risk factors, management, and outcomes of patients with STEMI, and highlight potential variations between countries that need further exploration.
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2022)
